Global burden of vaccine‐associated multiple sclerosis, 1967–2022: A comprehensive analysis of the international pharmacovigilance database

Journal of Medical Virology, Journal Year: 2024, Volume and Issue: 96(4)

Published: April 1, 2024

Abstract Vaccine‐associated multiple sclerosis (MS) is rare, with insufficient evidence from case reports. Given the scarcity of large‐scale data investigating association between vaccine administration and adverse events, we investigated global burden vaccine‐associated MS potential related vaccines 1967 to 2022. Reports on 2022 were obtained World Health Organization International Pharmacovigilance Database (total number reports = 120 715 116). We evaluated reports, reporting odds ratio (ROR), information components (IC) investigate associations 19 across 156 countries territories. identified 8288 among 132 980 cases all‐cause MS. The cumulative gradually increased over time, a substantial increase after 2020, owing COVID‐19 mRNA develops more frequently in males adolescents. Nine significantly associated higher reporting, highest disproportional observed for hepatitis B (ROR 19.82; IC 025 4.18), followed by encephalitis 7.42; 2.59), A 4.46; 1.95), papillomavirus 4.45; 2.01). Additionally, showed disproportionate signal 1.55; 0.52). Fatal clinical outcomes reported only 0.3% (21/8288) all Although various are potentially risk MS, should be cautious about following vaccination, particularly vaccines, consider factors

Language: Английский

National trends of allergic diseases and pandemic–related factors among individuals with obesity in South Korea: A nationwide representative serial study, 2005–2021

Heliyon, Journal Year: 2024, Volume and Issue: 10(9), P. e29921 - e29921

Published: April 22, 2024

Although obesity is known to be related allergic diseases, few studies have investigated the prevalence of diseases in individuals with obesity, especially during COVID-19 pandemic. Thus, this study aimed analyze national trends among and sociodemographic factors.

Language: Английский

National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: May 29, 2024

Abstract Previous studies have examined the prevalence of allergic diseases in adolescents 1–2 years after emergence COVID-19 pandemic. However, more data is needed to understand long-term impact on diseases. Thus, we aimed examine trend atopic dermatitis Korean before and during pandemic across 14 years. Additionally, analyze risk factors (AD) based results. The Disease Control Prevention Agency conducted Korea Youth Risk Behavior Web-based Survey from 2009 2022, which for this study were obtained. Prevalence trends compared subgroups, β difference (β diff ) was calculated. We computed odds ratios changes disease This included a total 917,461 participants 2022. increased 6.79% (95% CI 6.66–6.91) 2009–2011 6.89% 6.72–7.05) 2018–2019, then decreased slightly 5.82% 5.60–6.04) Across years, middle school student status, low parent’s highest education level, household income, non-alcohol consumption, non-smoker smoking no suicidal thoughts, suicide attempts associated with dermatitis, while female sex, rural residence, high BMI, performance, feelings sadness despair small increase. an 18-year, found that pre-pandemic start remained constant throughout could be explained mainly by large scale social political occurred

Language: Английский