COVID-19 Vaccine Acceptance and Hesitancy among Pregnant Women: A Knowledge, Attitude, and Perceived Risks Survey in Lusaka, Zambia

Pharmacology &amp Pharmacy, Journal Year: 2024, Volume and Issue: 15(05), P. 147 - 166

Published: Jan. 1, 2024

Introduction: The coronavirus disease 2019 (COVID-19) is an infectious of the respiratory tract caused by SARS-CoV-2. Since its emergence, there have been increased rates transmission and spread, morbidity mortality which led to development COVID-19 vaccines address pandemic. This study assessed acceptance, knowledge, attitude, perceived risks regarding among pregnant women attending antenatal care at two First-Level Hospitals in Lusaka, Zambia. Materials Methods: was a cross-sectional that conducted 241 using questionnaire from August 2023 October Lusaka district, collected data were analyzed IBM Statistical Package for Social Sciences (SPSS) version 22.0. analysis performed Chi-square test. statistical significance set 95% confidence level. Results: Of participants, 107 (42.7%) aged between 24 34 years. Overall, 64.3% accepted vaccines, 122 (50.6%) already vaccinated. Further, 203 (84.6%) had good 199 (82.6%) positive attitudes towards vaccines. However, 58.5% thought not safe could cause infertility. Alongside this, 70.1% harmful during pregnancy. Having knowledge associated with age (p = 0.049), education status 0.001), employment 0.001). attitude 0.001) Conclusion: found most attitudes, majority vaccine. Encouragingly, who Most side effects, safe, be Consequently, this contributed hesitancy receive vaccine some participants. findings demonstrate need provide continuous educational programs on benefits vaccinations themselves their children.

Language: Английский

Efficacy of vaccination during pregnancy in reducing the risk of SARS-CoV-2 infection in infants younger than 12 months. Puglia (Italy), 2021–23

Human Vaccines & Immunotherapeutics, Journal Year: 2024, Volume and Issue: 20(1)

Published: Sept. 17, 2024

This retrospective cohort study evaluated the effectiveness of maternal vaccination against COVID-19 in reducing risk SARS-CoV-2 infection infants younger than 12 months. The study, conducted at "Policlinico" University Hospital Bari, included 3346 newborns and their mothers. explored degree protection offered by depending on timing, type, trimester vaccination, also taking into account mother's history infection. We compared incidence rate between children vaccinated unvaccinated mothers; values were 10.2% 18.1%, respectively, difference was statistically significant. overall vaccine 45%. Further analysis revealed increasing efficacy as doses administered to mother increased case a previous Dual immune stimulation (vaccination natural infection) 83% effective preventing among newborns. multivariable models confirmed protective effect with all types vaccines used. infection's an interesting temporal trend, time, suggesting possible correlation persistence antibodies or gradual weaning. results capacity are line global literature. Strengths include sample size, robust methodology, multivariate analyses. Institutions could intensify awareness campaigns encourage both pregnant women those who would like become receive vaccination.

Language: Английский