Probiotics, Prebiotics, and Synbiotics on Constipation in Children with Cerebral Palsy DOI Creative Commons
Andrea García‐Contreras, Edgar M. Vásquez‐Garibay, Lucila A. Godínez-Méndez

et al.

IntechOpen eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 10, 2023

Constipation is a common gastrointestinal disorder in children with cerebral palsy, which affects up to 74%. Children palsy are at high risk of gut dysbiosis. Prebiotics and probiotics may modulate microbiota influence brain functions. Probiotics defined as “live organisms that, when administered adequate amounts, confer health benefit on the host.” substrate that selectively utilized by host microorganisms benefit. Both prebiotics have been shown improve an improvement characteristics stools such history painful defecation, presence fecal mass rectum, stool frequency palsy. A strong bidirectional communication between central nervous system enteric exists, known gut-brain axis, regulates motility, gastric secretion, blood flow, barrier integrity, immune response, visceral sensations. The use can production bioactive compounds impact gut-microbiota-brain axis functions

Language: Английский

Role of Inflammatory Mechanisms in Major Depressive Disorder: From Etiology to Potential Pharmacological Targets DOI Creative Commons
Bruna R. Kouba, Laura A. Borba, Pedro Borges de Souza

et al.

Cells, Journal Year: 2024, Volume and Issue: 13(5), P. 423 - 423

Published: Feb. 28, 2024

The involvement of central and peripheral inflammation in the pathogenesis prognosis major depressive disorder (MDD) has been demonstrated. increase pro-inflammatory cytokines (interleukin (IL)-1β, IL-6, IL-18, TNF-α) individuals with depression may elicit neuroinflammatory processes inflammation, mechanisms that, turn, can contribute to gut microbiota dysbiosis. Together, neuroinflammation dysbiosis induce alterations tryptophan metabolism, culminating decreased serotonin synthesis, impairments neuroplasticity-related mechanisms, glutamate-mediated excitotoxicity. This review aims highlight inflammatory (neuroinflammation, dysbiosis) involved pathophysiology MDD explore novel anti-inflammatory therapeutic approaches for this psychiatric disturbance. Several lines evidence have indicated that addition antidepressants, physical exercise, probiotics, nutraceuticals (agmatine, ascorbic acid, vitamin D) possess effects their antidepressant properties. Further studies are necessary benefits these alternative therapies MDD.

Language: Английский

Citations

73
Probiotic Functions in Fermented Foods: Anti-Viral, Immunomodulatory, and Anti-Cancer Benefits DOI Creative Commons
Yeonhee Pyo, Ki Han Kwon,

Yeon Ja Jung

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(15), P. 2386 - 2386

Published: July 28, 2024

Fermented foods can provide many benefits to our health. These are created by the action of microorganisms and help support digestive health immune system. include yogurt,

Language: Английский

Citations

12
Dynamic changes in the gut microbiota play a critical role in age-associated cognitive dysfunction via SCFAs and LPS synthesis metabolic pathways during brain aging DOI

Xiaoying Ma,

Jiaying Liu, Lei Jiang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140945 - 140945

Published: Feb. 11, 2025

Language: Английский

Citations

1
Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress DOI Creative Commons
Anil Patani, Deepak Balram, Virendra Kumar Yadav

et al.

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 30, 2023

Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern human health. The present review comprehensively examines various categories endocrine within glands, encompassing glucocorticoids, mineralocorticoids, and androgens. Additionally, comprehensive account hormone disorders, including insufficiency, Cushing’s syndrome, tumors, is presented, with particular emphasis on their intricate association oxidative stress. also delves into an examination nutritional antioxidants, namely vitamin C, E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, probiotics, elucidates role mitigating adverse effects stress arising imbalances levels. In conclusion, harnessing power antioxidants has potential to help caused by imbalance hormones. This could lead new research therapeutic interventions.

Language: Английский

Citations

17
Probiotics: Bridging the interplay of a healthy gut and psychoneurological well‐being DOI Creative Commons

Ashish Kumar Meher,

Biswajeet Acharya, Prafulla Kumar Sahu

et al.

Food Bioengineering, Journal Year: 2024, Volume and Issue: 3(1), P. 126 - 147

Published: March 1, 2024

Abstract The establishment of a healthy microbiota, particularly during infancy, profoundly influences psychological health and neurological function through the gut‐brain axis. This review delves into intricate connections between probiotics, gut microbiome development, their impact on disorders. Biotics, live microorganisms with proven benefits, have emerged as promising intervention, critical developmental stages. Administering specific probiotic strains ( Lactobacillus species Bifidobacterium ) in infancy has shown promise preventing alleviating disorders, implications for well‐being. bidirectional communication along axis underscores potential probiotics influencing outcomes, ranging from anxiety to neurodevelopmental Additionally, this explores emerging food engineering techniques (microencapsulation, genome editing, fermentation, protein engineering, immobilization, etc.) employed preparing probiotic‐based foods, ensuring viability targeted release gastrointestinal tract.

Language: Английский

Citations

7
Strain-specific effects of probiotics on depression and anxiety: a meta-analysis DOI Creative Commons
Maryam Rahmannia, Mohadeseh Poudineh, Roya Mirzaei

et al.

Gut Pathogens, Journal Year: 2024, Volume and Issue: 16(1)

Published: Sept. 8, 2024

Depression and anxiety are pervasive mental health disorders with substantial global burdens. Probiotics, live microorganisms known for their benefits, have emerged as a potential therapeutic intervention these conditions. This systematic review meta-analysis aim to evaluate the strain-specific effects of probiotics on relieving depressive symptoms while elucidating underlying mechanisms.

Language: Английский

Citations

7
Exploring Therapeutic Potential of Phytoconstituents as a Gut Microbiota Modulator in the Management of Neurological and Psychological Disorders DOI

Prarit Chandel,

Komal Thapa, Neha Kanojia

et al.

Neuroscience, Journal Year: 2024, Volume and Issue: 551, P. 69 - 78

Published: May 14, 2024

Language: Английский

Citations

4
Limited Changes in Red Blood Cell Parameters After Probiotic Supplementation in Depressive Individuals: Insights from a Secondary Analysis of the PRO-DEMET Randomized Controlled Trial DOI Open Access
Agata Gajewska, Adam Wysokiński, Dominik Strzelecki

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(1), P. 265 - 265

Published: Jan. 5, 2025

Background: Depression often coexists with anemia, potentially sharing common pathways, highlighting the need for treatments addressing both conditions simultaneously. This study evaluated effect of probiotics on red blood cell (RBC) parameters in adults depressive disorder. We hypothesized that would positively influence RBC parameters, modulated by baseline inflammation or dietary intake, improved function correlating better antidepressant outcomes. Methods: secondary analysis a two-arm, randomized, double-blind, controlled trial involved 116 Participants received probiotic formulation containing Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175 placebo 60 days. Data from 97 subjects were analyzed including hemoglobin (HGB), count, hematocrit (HCT), mean corpuscular volume (MCV), concentration (MCH), (MCHC), distribution width (RDW). Results: Probiotic supplementation did not result significant changes compared to placebo. However, may help stabilize HGB, HCT, MCH, MCHC levels, preventing fluctuations observed group. Conclusions: While showed potential benefits symptoms, observed. Larger studies are needed clarify mechanisms clinical implications.

Language: Английский

Citations

0
Progress in Probiotic Science: Prospects of Functional Probiotic‐Based Foods and Beverages DOI Creative Commons
Musaalbakri Abdul Manan

International Journal of Food Science, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

This comprehensive review explores the evolving role of probiotic‐based foods and beverages, highlighting their potential as functional “ future ” that could significantly enhance nutrition, health, overall well‐being. These products are gaining prominence for benefits in gut immune support, holistic wellness. However, success depends on addressing critical safety concerns navigating administrative complexities. Ensuring these do more good than harm involves rigorous evaluations probiotic strains, particularly those sourced from human gastrointestinal tract. Lactic acid bacteria (LABs) serve versatile effective starter cultures development beverages. The emphasizes LABs precision probiotics advancing products. Establishing standardized guidelines transparent practices is essential, requiring collaboration among regulatory bodies, industry stakeholders, scientific community. underscores importance innovation developing friendly ,” super fermentation, assessments. prospects beverages rely refining elements adapting to emerging advancements. Ultimately, empowering consumers with accurate information, fostering innovation, maintaining stringent standards will shape trusted beneficial components a health‐conscious society. Probiotic‐based often infused LABs, designed health.

Language: Английский

Citations

0
Gut-brain connection in schizophrenia: A narrative review DOI
Asma Iqbal, Syed Faqeer Hussain Bokhari,

Muneeb Ur Rehman

et al.

World Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 15(5)

Published: April 30, 2025

Schizophrenia is a complex neuropsychiatric disorder characterized by cognitive, emotional, and behavioral impairments. The microbiota-gut-brain axis crucial in its pathophysiology, mediating communication between the gut brain through neural, immune, endocrine, metabolic pathways. Dysbiosis, or an imbalance microbiota, linked to neuroinflammation, systemic inflammation, neurotransmitter disruptions, all of which contribute symptoms schizophrenia. Gut microbiota-derived metabolites, such as short-chain fatty acids, influence function, including immune responses synthesis. These findings suggest that microbial imbalances exacerbate schizophrenia, providing novel perspective on disorder’s underlying mechanisms. Emerging microbiota-targeted therapies—such probiotics, prebiotics, dietary interventions, fecal microbiota transplantation—show promise adjunctive treatments, aiming restore balance improve clinical outcomes. While further research needed, targeting offers innovative approach schizophrenia management, with potential enhance patient outcomes quality life.

Language: Английский

Citations

0