IntechOpen eBooks,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 10, 2023
Constipation
is
a
common
gastrointestinal
disorder
in
children
with
cerebral
palsy,
which
affects
up
to
74%.
Children
palsy
are
at
high
risk
of
gut
dysbiosis.
Prebiotics
and
probiotics
may
modulate
microbiota
influence
brain
functions.
Probiotics
defined
as
“live
organisms
that,
when
administered
adequate
amounts,
confer
health
benefit
on
the
host.”
substrate
that
selectively
utilized
by
host
microorganisms
benefit.
Both
prebiotics
have
been
shown
improve
an
improvement
characteristics
stools
such
history
painful
defecation,
presence
fecal
mass
rectum,
stool
frequency
palsy.
A
strong
bidirectional
communication
between
central
nervous
system
enteric
exists,
known
gut-brain
axis,
regulates
motility,
gastric
secretion,
blood
flow,
barrier
integrity,
immune
response,
visceral
sensations.
The
use
can
production
bioactive
compounds
impact
gut-microbiota-brain
axis
functions
Cells,
Journal Year:
2024,
Volume and Issue:
13(5), P. 423 - 423
Published: Feb. 28, 2024
The
involvement
of
central
and
peripheral
inflammation
in
the
pathogenesis
prognosis
major
depressive
disorder
(MDD)
has
been
demonstrated.
increase
pro-inflammatory
cytokines
(interleukin
(IL)-1β,
IL-6,
IL-18,
TNF-α)
individuals
with
depression
may
elicit
neuroinflammatory
processes
inflammation,
mechanisms
that,
turn,
can
contribute
to
gut
microbiota
dysbiosis.
Together,
neuroinflammation
dysbiosis
induce
alterations
tryptophan
metabolism,
culminating
decreased
serotonin
synthesis,
impairments
neuroplasticity-related
mechanisms,
glutamate-mediated
excitotoxicity.
This
review
aims
highlight
inflammatory
(neuroinflammation,
dysbiosis)
involved
pathophysiology
MDD
explore
novel
anti-inflammatory
therapeutic
approaches
for
this
psychiatric
disturbance.
Several
lines
evidence
have
indicated
that
addition
antidepressants,
physical
exercise,
probiotics,
nutraceuticals
(agmatine,
ascorbic
acid,
vitamin
D)
possess
effects
their
antidepressant
properties.
Further
studies
are
necessary
benefits
these
alternative
therapies
MDD.
Foods,
Journal Year:
2024,
Volume and Issue:
13(15), P. 2386 - 2386
Published: July 28, 2024
Fermented
foods
can
provide
many
benefits
to
our
health.
These
are
created
by
the
action
of
microorganisms
and
help
support
digestive
health
immune
system.
include
yogurt,
Frontiers in Endocrinology,
Journal Year:
2023,
Volume and Issue:
14
Published: Nov. 30, 2023
Oxidative
stress,
resulting
from
dysregulation
in
the
secretion
of
adrenal
hormones,
represents
a
major
concern
human
health.
The
present
review
comprehensively
examines
various
categories
endocrine
within
glands,
encompassing
glucocorticoids,
mineralocorticoids,
and
androgens.
Additionally,
comprehensive
account
hormone
disorders,
including
insufficiency,
Cushing’s
syndrome,
tumors,
is
presented,
with
particular
emphasis
on
their
intricate
association
oxidative
stress.
also
delves
into
an
examination
nutritional
antioxidants,
namely
vitamin
C,
E,
carotenoids,
selenium,
zinc,
polyphenols,
coenzyme
Q10,
probiotics,
elucidates
role
mitigating
adverse
effects
stress
arising
imbalances
levels.
In
conclusion,
harnessing
power
antioxidants
has
potential
to
help
caused
by
imbalance
hormones.
This
could
lead
new
research
therapeutic
interventions.
Food Bioengineering,
Journal Year:
2024,
Volume and Issue:
3(1), P. 126 - 147
Published: March 1, 2024
Abstract
The
establishment
of
a
healthy
microbiota,
particularly
during
infancy,
profoundly
influences
psychological
health
and
neurological
function
through
the
gut‐brain
axis.
This
review
delves
into
intricate
connections
between
probiotics,
gut
microbiome
development,
their
impact
on
disorders.
Biotics,
live
microorganisms
with
proven
benefits,
have
emerged
as
promising
intervention,
critical
developmental
stages.
Administering
specific
probiotic
strains
(
Lactobacillus
species
Bifidobacterium
)
in
infancy
has
shown
promise
preventing
alleviating
disorders,
implications
for
well‐being.
bidirectional
communication
along
axis
underscores
potential
probiotics
influencing
outcomes,
ranging
from
anxiety
to
neurodevelopmental
Additionally,
this
explores
emerging
food
engineering
techniques
(microencapsulation,
genome
editing,
fermentation,
protein
engineering,
immobilization,
etc.)
employed
preparing
probiotic‐based
foods,
ensuring
viability
targeted
release
gastrointestinal
tract.
Gut Pathogens,
Journal Year:
2024,
Volume and Issue:
16(1)
Published: Sept. 8, 2024
Depression
and
anxiety
are
pervasive
mental
health
disorders
with
substantial
global
burdens.
Probiotics,
live
microorganisms
known
for
their
benefits,
have
emerged
as
a
potential
therapeutic
intervention
these
conditions.
This
systematic
review
meta-analysis
aim
to
evaluate
the
strain-specific
effects
of
probiotics
on
relieving
depressive
symptoms
while
elucidating
underlying
mechanisms.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(1), P. 265 - 265
Published: Jan. 5, 2025
Background:
Depression
often
coexists
with
anemia,
potentially
sharing
common
pathways,
highlighting
the
need
for
treatments
addressing
both
conditions
simultaneously.
This
study
evaluated
effect
of
probiotics
on
red
blood
cell
(RBC)
parameters
in
adults
depressive
disorder.
We
hypothesized
that
would
positively
influence
RBC
parameters,
modulated
by
baseline
inflammation
or
dietary
intake,
improved
function
correlating
better
antidepressant
outcomes.
Methods:
secondary
analysis
a
two-arm,
randomized,
double-blind,
controlled
trial
involved
116
Participants
received
probiotic
formulation
containing
Lactobacillus
helveticus
Rosell®-52
and
Bifidobacterium
longum
Rosell®-175
placebo
60
days.
Data
from
97
subjects
were
analyzed
including
hemoglobin
(HGB),
count,
hematocrit
(HCT),
mean
corpuscular
volume
(MCV),
concentration
(MCH),
(MCHC),
distribution
width
(RDW).
Results:
Probiotic
supplementation
did
not
result
significant
changes
compared
to
placebo.
However,
may
help
stabilize
HGB,
HCT,
MCH,
MCHC
levels,
preventing
fluctuations
observed
group.
Conclusions:
While
showed
potential
benefits
symptoms,
observed.
Larger
studies
are
needed
clarify
mechanisms
clinical
implications.
International Journal of Food Science,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
This
comprehensive
review
explores
the
evolving
role
of
probiotic‐based
foods
and
beverages,
highlighting
their
potential
as
functional
“
future
”
that
could
significantly
enhance
nutrition,
health,
overall
well‐being.
These
products
are
gaining
prominence
for
benefits
in
gut
immune
support,
holistic
wellness.
However,
success
depends
on
addressing
critical
safety
concerns
navigating
administrative
complexities.
Ensuring
these
do
more
good
than
harm
involves
rigorous
evaluations
probiotic
strains,
particularly
those
sourced
from
human
gastrointestinal
tract.
Lactic
acid
bacteria
(LABs)
serve
versatile
effective
starter
cultures
development
beverages.
The
emphasizes
LABs
precision
probiotics
advancing
products.
Establishing
standardized
guidelines
transparent
practices
is
essential,
requiring
collaboration
among
regulatory
bodies,
industry
stakeholders,
scientific
community.
underscores
importance
innovation
developing
friendly
,”
super
fermentation,
assessments.
prospects
beverages
rely
refining
elements
adapting
to
emerging
advancements.
Ultimately,
empowering
consumers
with
accurate
information,
fostering
innovation,
maintaining
stringent
standards
will
shape
trusted
beneficial
components
a
health‐conscious
society.
Probiotic‐based
often
infused
LABs,
designed
health.
World Journal of Psychiatry,
Journal Year:
2025,
Volume and Issue:
15(5)
Published: April 30, 2025
Schizophrenia
is
a
complex
neuropsychiatric
disorder
characterized
by
cognitive,
emotional,
and
behavioral
impairments.
The
microbiota-gut-brain
axis
crucial
in
its
pathophysiology,
mediating
communication
between
the
gut
brain
through
neural,
immune,
endocrine,
metabolic
pathways.
Dysbiosis,
or
an
imbalance
microbiota,
linked
to
neuroinflammation,
systemic
inflammation,
neurotransmitter
disruptions,
all
of
which
contribute
symptoms
schizophrenia.
Gut
microbiota-derived
metabolites,
such
as
short-chain
fatty
acids,
influence
function,
including
immune
responses
synthesis.
These
findings
suggest
that
microbial
imbalances
exacerbate
schizophrenia,
providing
novel
perspective
on
disorder’s
underlying
mechanisms.
Emerging
microbiota-targeted
therapies—such
probiotics,
prebiotics,
dietary
interventions,
fecal
microbiota
transplantation—show
promise
adjunctive
treatments,
aiming
restore
balance
improve
clinical
outcomes.
While
further
research
needed,
targeting
offers
innovative
approach
schizophrenia
management,
with
potential
enhance
patient
outcomes
quality
life.