Clinical-Diagnostic and Therapeutic Advances in Feline Hypertrophic Cardiomyopathy DOI Creative Commons
Felipe Gaia de Sousa, Ana Cristina Mendes, Luísa Carvalho

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(3), P. 289 - 289

Published: March 19, 2025

A comprehensive literature review was conducted to summarise existing evidence and the latest therapeutic advancements in feline HCM. The disease phenotype is characterised by development of concentric hypertrophy, which variable but often asymmetric, primarily affecting left ventricle. HCM marked diastolic dysfunction, resulting a reduced intracavitary internal diameter due disordered alignment cardiomyocytes excessive collagen deposition, thickens myocardial tissue impairs relaxation. There strong supporting role genetic mutations sarcomeric genes Clinical signs vary are frequently associated with congestive heart failure (CHF) ATE. Diagnosis based on combination clinical evaluation, laboratory tests, imaging studies, although certain aspects remain insufficiently understood require further research. Therapeutic management focuses controlling signs, slowing progression, improving both quality life expectancy. However, ongoing studies essential refine diagnostic strategies explore novel treatment options for better management.

Language: Английский

Clinical-Diagnostic and Therapeutic Advances in Feline Hypertrophic Cardiomyopathy DOI Creative Commons
Felipe Gaia de Sousa, Ana Cristina Mendes, Luísa Carvalho

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(3), P. 289 - 289

Published: March 19, 2025

A comprehensive literature review was conducted to summarise existing evidence and the latest therapeutic advancements in feline HCM. The disease phenotype is characterised by development of concentric hypertrophy, which variable but often asymmetric, primarily affecting left ventricle. HCM marked diastolic dysfunction, resulting a reduced intracavitary internal diameter due disordered alignment cardiomyocytes excessive collagen deposition, thickens myocardial tissue impairs relaxation. There strong supporting role genetic mutations sarcomeric genes Clinical signs vary are frequently associated with congestive heart failure (CHF) ATE. Diagnosis based on combination clinical evaluation, laboratory tests, imaging studies, although certain aspects remain insufficiently understood require further research. Therapeutic management focuses controlling signs, slowing progression, improving both quality life expectancy. However, ongoing studies essential refine diagnostic strategies explore novel treatment options for better management.

Language: Английский

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