Nutritional value, HPLC-DAD analysis and biological activities of Ceratonia siliqua L. pulp based on in vitro and in silico studies DOI Creative Commons
Salah Laaraj, Aziz Tikent, Chaimae El-rhouttais

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Language: Английский

Nutritional composition health benefits and quality of fresh and dried figs from Eastern Morocco DOI Creative Commons
Aziz Tikent, Salah Laaraj,

Atman Adiba

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 21, 2025

The fig tree is a multifaceted plant with wide range of nutritional and health benefits. employment the Aksoy weighted classification method, predicated on biological characteristics pertaining to ripening period, in conjunction pomological chemical fresh fruit, yielded favorable outcomes assessment quality from eastern Morocco, particularly OnK Hmam (718) Chetoui (720) varieties, indicating high quality. From commercial perspective, weight figs key factor determining their value. study examined five different varieties figs, revealing significant variations average weight. Malha recorded lowest 30.24 g, while Onk exhibited highest 57.25 g. Fresh has content total sugar (15.04%), titratable acid (0.272%), potassium (266.8 mg/100 g), sodium (0.580 calcium (75.20 g) phosphorus (30.04 mg). fibre concentration (2.60%). Bounacer magnesium (20.52 g). Ghoudane iron (1.24 polyphenols (275.6 GAE/100 g FW) flavonoids (120.3 QE/100 among samples. As are seasonal perishable, most effective method preserving benefits over an extended period through drying process. primary objective process dehydrate reduce water activity acceptable level. In addition, storage transport costs incurred economically commercially advantageous. Sun-dried goudane chetoui characterized by elevated sugar, fiber, mineral, antioxidant content. Additionally, they exhibit volume reduction, thereby reducing packaging requirements rendering them optimal for use as dietary supplements. meet required criteria ≤ 26.0% dry matter minimum diameter 18 mm black (Ghoudane) 22 white (Chetoui) European standards. However, it should be noted that marketability limited Category I (65 < maximum allowable fruit count per kilogram 120), which includes lower designations. Dried was found contain higher levels (380.9 mg DW) (100.1 than dried (305.9 DW 81.90 EQ/100 DW). After sun Chetoui, Principal Component Analysis (PCA) showed had increased phenolic content, minerals. flavonoid vitamin C soluble solids decreased.

Language: Английский

Citations

0

Combining In Vitro, In Vivo, and In Silico Approaches to Explore the Effect of Ceratonia siliqua and Ocimum basilicum Rich Phenolic Formula on Lipid Metabolism and Plasma Lipoprotein Oxidation in Mice Fed a High-Fat Diet: A Follow-Up Study DOI Creative Commons
Mohammadine Moumou,

Amani Tayebi,

Abderrahmane Hadini

et al.

Metabolites, Journal Year: 2025, Volume and Issue: 15(1), P. 36 - 36

Published: Jan. 10, 2025

Background/Objectives: Hyperlipidemia is a serious risk factor for cardiovascular diseases and liver steatosis. In this work, we explored the effect of an herbal formula (CBF) containing immature Ceratonia siliqua pods Ocimum basilicum extracts on lipid metabolism disorders lipoprotein-rich plasma (LRP) oxidation in mice. Methods: The phenolic composition was determined using HPLC-DAD analysis. antioxidant activity studied various vitro methods. Acute toxicity evaluated Importantly, CBF investigated high-fat diet (HFD) hyperlipidemia mouse model. An silico study carried out to predict underlying mechanisms. Results: HPLC analysis revealed gallic acid, cinnamic naringenin as major phenolics carob pod aqueous extract. Concerning basil hydro-ethanolic extract, rosmarinic, chicoric, caftaric, caffeic acids were main phenolics. Accordingly, prevented LRP concentration-dependent manner. This not toxic mice (LD50 > 2000 mg/kg body weight). Moreover, animals administered at 200 mg/kg/day presented significant decline their weight gain, adipose tissue weight, total cholesterol, low-density lipoprotein cholesterol (LDL-C) level, glycaemia after 10 weeks’ treatment. decreased atherogenic index LDL-C HDL-C ratio reduced level fats accumulated liver. molecular docking that caftaric acids, bound particularly strongly many proteins involved regulation metabolism. includes HMG-CoA reductase, PPARα/γ, PCSK9, Cyp7a1, ATP-citrate lyase. Conclusions: could be good source natural supplements, functional foods, pharmaceuticals effective managing oxidative stress preventing related disorders.

Language: Английский

Citations

0

Nutritional value, HPLC-DAD analysis and biological activities of Ceratonia siliqua L. pulp based on in vitro and in silico studies DOI Creative Commons
Salah Laaraj, Aziz Tikent, Chaimae El-rhouttais

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Language: Английский

Citations

2