Metabolites,
Journal Year:
2024,
Volume and Issue:
15(1), P. 6 - 6
Published: Dec. 31, 2024
In
this
study,
we
present
a
novel
approach
using
amperometric
microsensors
to
detect
quercetin
in
cosmetic
formulations
and
track
its
metabolic
behavior
after
topical
application.
This
method
offers
sensitive,
real-time
alternative
conventional
techniques,
enabling
the
detection
of
quercetin’s
bioavailability,
transformation
into
active
metabolites,
potential
therapeutic
effects
when
applied
skin.
Quercetin
(Q)
is
bioactive
flavonoid
known
for
potent
antioxidant
properties,
naturally
numerous
plants,
particularly
those
with
applications
formulations.
response
growing
interest
developing
plant-based
dermo-cosmetic
solutions,
study
investigates
electrochemical
quercetin,
ketone-type
flavonoid,
extracted
from
Gingko
biloba
essential
oil.
Three
newly
designed
were
developed
assess
their
efficacy
detecting
botanical
samples.
The
sensor
configurations
utilized
two
forms
carbon
material
as
foundation:
graphite
(G)
nanoparticles
(CNs).
These
base
materials
modified
paraffin
oil,
chitosan
(CHIT),
cobalt(II)
tetraphenylporphyrin
(Co(II)TPP)
enhance
sensitivity.
Differential
pulse
voltammetry
(DPV)
served
analytical
investigation.
Among
sensors,
CHIT/G–CN
microsensor
exhibited
highest
sensitivity,
limit
1.22
×
10−7
mol
L−1,
followed
by
G–CN
(5.64
10−8
L−1)
Co(II)TPP/G–CN
(9.80
microsensors.
minimum
detectable
concentration
was
observed
CoP/G–CN
microsensors,
achieving
threshold
low
0.0001
μmol
L−1.
Recovery
rates
relative
standard
deviation
(RSD)
values
averaged
97.4%
±
0.43,
underscoring
sensors’
reliability
matrices.
BMC Complementary Medicine and Therapies,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 4, 2025
Honey
has
been
successfully
used
in
wound
care
and
cosmetics
because
of
its
effective
biological
properties,
including
antibacterial,
antioxidant,
anti-inflammatory
activities.
Polyphenols,
particularly
phenolic
acids,
are
key
honey
components
responsible
for
these
beneficial
effects.
In
recent
years,
there
a
growing
demand
natural,
ecologically
friendly,
biodegradable
products
the
modern
market.
This
study
aimed
to
identify
quantify
acids
four
Polish
samples
different
botanical
origins
(heather,
buckwheat,
linden
rapeseed)
assess
first
time
permeation
identified
through
skin
their
accumulation
after
application
pure
samples,
as
well
honey-based
hydrogel
emulsion
formulations.
The
samples'
antioxidant
activity
total
content
were
determined
using
DPPH
ABTS
assays
Folin-Ciocalteu
method,
respectively.
Phenolic
volatile
compounds
quantified
HPLC-UV
GC-MS
biocompatibility
was
evaluated
murine
fibroblast
cell
line
(L929).
A
Franz-type
vertical
diffusion
with
porcine
acid's
from
pharmaceutical
biodegradability
prepared
formulations
also
characterised.
Gallic
acid,
3,4-dihydroxybenzoic
2,5-dihydroxybenzoic
coumaric
3-hydroxybenzoic
acid
samples.
Heather
exhibited
significantly
higher
polyphenol
than
other
Heather,
buckwheat
decreased
viability
at
concentrations
5%
2.5%,
while
rapeseed
sample
markedly
reduced
only
5%.
Among
tested
-
honey,
hydrogel,
rates
observed
hydrogels
honeys
emulsions.
Additionally,
classified
partially
biodegradable.
obtained
results
confirmed
effectiveness
two
form
or
containing
applied
topically.
inclusion
vehicle,
particular
increased
penetration
skin.
International Journal of Cosmetic Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 12, 2025
Abstract
Honeybees'
success
is
strictly
linked
to
the
chemical
and
application
properties
of
their
products:
honey,
beeswax
(BW),
venom,
propolis,
pollen
royal
jelly.
Among
these
products,
BW,
a
natural
compound
secreted
by
bees,
particularly
valued
for
its
stability
widely
used
in
cosmetics
make‐up
skincare
production
or
dermatology
produce
creams.
In
recent
years,
there
has
been
growing
awareness
critical
role
insects
play
ecosystem.
Animal‐derived
ingredients
are
controversial
borderline
with
consumers'
necessities.
Therefore,
whenever
possible,
similar
from
other
sources
sought.
The
demand
vegan
products
global
trend
that
influences
all
segments
consumer
behaviour,
including
choice
cosmetics.
Given
eco‐friendly
commonly
lipstick
formulations,
needs
be
replaced
alternative.
this
paper,
we
report
development
completely
lipstick.
To
predict
behaviour
structuring
wax
complex
system,
compatibility
study
ABWAX®
MIMIC
BEESWAX
MK,
alternative
(vBWA),
oils
colours
was
performed.
MK
WHITE
F.U.
demonstrated
thermal
characteristics
penetration
curves,
showing
overall
comparable
performances
finished
products.
We
can
conclude
could
an
innovative
highly
effective
animal‐derived
waxes
International Journal of Cosmetic Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 11, 2025
Abstract
Objective
Consumer's
growing
environmental
awareness
influences
purchasing
behaviour,
prompting
the
cosmetics
industry
to
adopt
sustainable
practices
based
on
a
circular
economy,
using
agro‐industrial
by‐products
as
cosmetic
ingredients.
This
study
assessed
feasibility
of
cork
powder,
an
abundant
by‐product
industry,
ingredient.
Key
challenges
were
identified,
and
effective
solutions
proposed
for
integrating
powder
into
products.
Methods
To
obtain
suitable
ingredient,
was
subjected
physical
treatment.
The
resulting
heat‐treated
further
characterized
particle
size,
colour,
moisture
content,
hygroscopicity,
pH,
oil
absorption
capacity
heavy
metal
content.
stability
both
stand‐alone
ingredient
incorporated
makeup
formulation,
evaluated
over
90
days,
its
safety
in
human
keratinocytes
3D
EpiSkin™
model.
Results
Cork
exhibited
brownish
low
content
(3.03
±
0.42%)
hygroscopic
properties
(9.04
0.08%),
along
with
high
(206.93
2.33
g/100
g)
acceptable
metals
levels,
considering
intended
use
(As
=
0.350
0.020
ppm;
Cd
0.086
0.003
Hg
0.005
0.001
Pb
1.420
0.030
ppm),
which
remained
stable
at
least
days.
skin
application
also
ensured
up
5%
Using
2%
O/W
formulations
provided
colour
shade
foundations
90‐day
period.
Conclusion
transforming
ingredients
include
standardization
preparation
process,
batch
uniformity
microbiological
burden.
Sieving,
washing,
filtration
heat
treatment
reduced
microbial
burden
improved
uniformity.
Industrial
processing
did
not
introduce
contaminants,
levels
remaining
below
regulatory
limits
use.
storage
conditions
adopted
preserved
physicochemical
properties,
pre‐formulation
studies
validated
potential
innovative
decorative
mattifying
cosmetics.
Transforming
is
stepwise
process
that
must
be
carefully
carried
out
ensure
optimal
performance.
