The sperm quality change in 6 months recovery from COVID-19 : a retrospective observational study
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 17, 2025
Abstract
XZ
and
YZ
performed
the
data
analyses
drafted
manuscript.
NJ,
KL
JX
participated
in
collection.
design
of
study
coordination.
ZL
TX
had
main
responsibility
for
design,
analyses,
interpretation,
writing
All
authors
read
approved
final
Background
The
COVID-19
pandemic
has
yielded
substantial
evidence
indicating
that
virus
may
possess
reproductive
toxicity
effects
adversely
affect
sperm
quality.
Given
sex-specific
implications
these
findings,
it
is
imperative
to
reliably
assess
reversibility
this
damage,
determine
precise
recovery
time,
evaluate
male
health
parameters
post-infection.
Methods
Male
patients
who
underwent
analysis
prior
infection
were
enrolled
a
observational
trial
changes
quality
during
6-month
period
from
COVID-19.
Sperm
dynamic
collected
at
five
consecutive
time
points:
before
1,
2,
3,
6
months
following
infection.
Quality
life,
psychological
status,
sexual
function
patients,
evaluated
with
questionnaires,
first
month
after
primary
outcomes
concentration
(Con)
progressive
motility
rate
(PR%).
Generalized
Estimating
Equations
(GEEs)
was
used
perform
statistical
comparisons
on
repeatedly
measured
variables.
Kaplan-Meier
survival
employed
observe
trend
over
time.
Results
1,009
subjects
widespread
COVID-19,
April
2022
January
2023.
Of
139
eligible
have
completed
infection,
92
(66%)
testing
second
month,
72
(52%)
third
64
(46%)
sixth
month.
Con
[39·22
(95%CI,
32·02–46·41)]
PR
[36·41
3229-40·53)]
significantly
decreased
post-infection
compared
pre-infection.
demonstrated
gradual
At
end
our
six-month
observation
period,
continue
be
lower
than
levels
observed
Survival
curve
indicated
that,
average,
duration
4·37
required
achieve
an
80%
level
During
no
significant
adverse
impacts
participants'
diverse
scores.
Discussion
indeed
influenced
by
but
temporary,
4–5
months.
Furthermore,
notable
alterations
men's
psychological,
urinary
symptoms,
or
initial
Language: Английский
Mapping the Scientometric Landscape of Andrology: Trends, Gaps, and Future Directions in Male Reproductive Health: A Scoping Review
The World Journal of Men s Health,
Journal Year:
2025,
Volume and Issue:
43
Published: Jan. 1, 2025
Language: Английский