Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 3, 2025

The field of pharmacogenetics (PGx) is experiencing significant growth, with increasing evidence to support its application in psychiatric care, suggesting potential personalize treatment plans, optimize medication efficacy, and reduce adverse drug reactions. However, the perceived utility practicability PGx for youth remains underexplored. This study investigated barriers attitudes Australian young adults towards implementation testing guide antidepressant primary care. Semi-structured focus groups interviews were conducted 17 participants aged between 18 24 years. These sessions recorded transcribed before thematic analysis was used identify collective themes. Three key themes identified, including prescription process, concerns testing, clinical implementation. Although positively by most participants, all shared about testing. Participants voiced financial impact delays, accuracy guiding treatment. Additionally, noted that low awareness willingness general practitioners incorporate into routine practice could hinder successful Prior practices, it essential acknowledge patient perspectives ensure practices remain patient-focused. highlights important considerations integrating pharmacotherapy emphasizes need future research address mitigate adults.

Language: Английский

The Impact of the COVID-19 Pandemic on Forensic Psychiatric Examination

Diagnostics, Journal Year: 2025, Volume and Issue: 15(4), P. 483 - 483

Published: Feb. 17, 2025

Background/Objectives: Forensic psychiatric expertise significantly contributes to clinical criminology. Interdisciplinary investigations, evaluation tactics, and the use of criminology indices are essential for psychosocial prognostic assessments conflict, aggression, adaptability, recovery. Methods: This study aims assess impact COVID-19 pandemic on forensic by analyzing demographic variables such as age, gender, background, other relevant data including criminal records, antecedents, personal pathological diagnosis, discernment. Our included 186 patients categorized into post-pandemic periods. Results: Most participants were male, with no significant rural–urban distribution differences. During COVID period, common acts aggression child pornography, followed attempted murder. A association was found between discernment disorders (p < 0.0011), 67.6% lacking having mental illnesses. Legal outcomes varied discernment; 60.3% without required mandatory hospitalization 0.0011). Conclusions: Medico-legal antecedents more frequent during pandemic, safety measures commonly applied those

Language: Английский

Exploring Youth-Perceived Barriers and Attitudes Towards the Clinical Use of Pharmacogenetic Testing to Optimise Antidepressant Pharmacotherapy

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 26, 2024

Abstract The field of pharmacogenetics (PGx) is experiencing significant growth, with increasing evidence to support its application in psychiatric care, suggesting potential personalise treatment plans, optimise medication efficacy, and reduce adverse drug reactions. However, the perceived utility practicability PGx for youth remains underexplored. This study investigated youth-perceived barriers attitudes towards implementation testing guide antidepressant primary care. Semi-structured focus groups interviews were conducted 17 participants aged between 18 24 years. These sessions recorded transcribed before thematic analysis was used identify collective themes. Three key themes identified, including prescription process, concerns testing, clinical implementation. Although positively by most participants, all shared about testing. Participants voiced financial impact delays, accuracy guiding treatment. Additionally, noted that low awareness willingness general practitioners incorporate into routine practice could hinder successful Prior Australian practices, it essential acknowledge patient perspectives ensure practices remain patient-focused. highlights important considerations integrating pharmacotherapy emphasizes need future research address mitigate barriers.

Language: Английский