Stannum Jurnal Sains dan Terapan Kimia,
Journal Year:
2024,
Volume and Issue:
6(1), P. 21 - 27
Published: May 1, 2024
While
UV
light
has
benefits
for
life,
excessive
exposure
to
also
negative
effects
on
humans.
Examples
of
the
include
cancer.
Therefore,
exploration
materials
that
can
be
used
as
anti-UV
continues
grow.
One
them
is
extract
from
Leucaena
leucocephala
leaves.
To
study
potential
a
compound
anti-UV,
one
method
use
molecular
modeling
approach
using
semi-empirical
method.
Based
this,
8
flavone-derived
compounds
contained
in
L.
leaf
were
modeled
with
PM3
method,
and
electronic-transition
was
calculated
ZINDO/S.
The
geometry
optimization
results
showed
bond
length
between
carbon
atoms
flavonoid
tururnans
did
not
change
significantly
difference
functional
groups.
However,
there
significant
dihedral
angle
due
repulsion
electronic
transition
calculation
all
derivatives
1-8
are
active
A,
B,
C
regions.
So
it
said
flavones
have
anti-UV.
In
addition,
energy
level
HOMO-LUMO
calculated.
Flavonoid
1
smallest
Eg
while
largest
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(8), P. 3302 - 3302
Published: April 14, 2024
The
aim
of
this
study
was
to
determine
the
types
UV
filters
used
in
adult
and
children’s
sunscreen
products
sold
Poland
(part
EU
market)
their
frequency
use.
INCI
compositions
were
collected
analyzed
for
presence
filters.
included
150
randomly
selected
preparations
adults
(from
71
brands)
50
children
33
brands).
survey
concerned
listed
Annex
VI
Regulation
(EC)
No
1223/2009
European
Parliament
Council
30
November
2009
on
cosmetic
products.
most
frequently
child
sunscreens
triazine
derivatives:
bis-ethylhexyloxyphenol
methoxyphenyl
(60.0%)
ethylhexyl
triazone
(52.0%),
salicylate
(46.0%),
a
derivative
salicylic
acid.
common
butyl
methoxydibenzoylmethane
(56.0%),
dibenzoylmethane
derivative,
followed
by
acid
(54.7%)
derivatives
(50.0%).
Physical
filters,
including
nano
non-nano
forms,
more
popular
children,
i.e.,
50.0%
(TiO2)
22.0%
(ZnO),
than
adults:
21.3%
6.7%
(ZnO).
For
both
many
contained
four
or
five
per
preparation;
however,
often
two
To
summarize,
following
dominate
photoprotectors
children:
methoxydibenzoylmethane,
triazine,
triazone,
salicylate,
diethylamino
hydroxybenzoyl
hexyl
benzoate.
Langmuir,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 7, 2025
Inclusion
complexation
of
the
sunscreen
ingredient
avobenzone
(AVB)
with
β-cyclodextrin
(β-CD)
was
investigated
to
improve
its
aqueous
solubility
and
photostability;
another
ultraviolet
(UV)
filter,
oxybenzone
(OXB),
phytochemical
antioxidant
curcumin
(CUR)
served
as
a
comparison.
In
this
study,
1-octanol/water
partition
coefficients,
acid
dissociation
constants,
phase-solubility
diagrams
β-CD,
ultraviolet–visible
(UV–vis)
spectral
changes
induced
by
UVA1
(365
nm)
irradiation
were
evaluated.
β-CD
at
concentrations
50–100
times
that
AVB
most
effectively
protected
photostability
AVB.
Additionally,
an
UVA1-insensitive
species
diketo
tautomer,
which
has
UVC-absorbing
band
potential
cause
photodegradation,
stored
in
inclusion
complex.
Acetonitrile–water
mixtures
various
volume
ratios
screened
mimic
internal
cavity
for
tautomeric
using
nuclear
magnetic
resonance
(NMR)
integrals
components.
The
results
indicated
provides
hydrophobic
environment
similar
40–50%
acetonitrile
solution
enhances
However,
excess
hyperchromic
effect
on
tautomer.
Aggregation
AVB/β-CD
complexes
≥2
mM
UVC
absorption.
To
avoid
molar
ratio
is
recommended
optimal
composition.
This
study
newly
exhibited
mitigates
reactivity
toward
inducing
tautomer
form
within
cavity.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(22), P. 5409 - 5409
Published: Nov. 16, 2024
Overexposure
to
ultraviolet
radiation
mainly
leads
skin
disorders
(erythema,
burns,
immunosuppression),
aging,
and
cancer
as
the
most
serious
side
effect.
It
has
been
widely
accepted
that
using
sunscreen
products
is
an
important
way
protect
against
harmful
effects
of
UV
rays.
Although
commercial
sunscreens
have
constantly
changed
improved
over
time,
there
are
emerging
concerns
about
safety
conventional,
organic,
filters
due
adverse
on
humans
(such
photoallergic
dermatitis,
contact
sensitivity,
endocrine-disrupting
effects,
etc.)
well
accumulation
in
environment
aquatic
organisms.
This
why
natural
compounds
increasingly
being
investigated
used
cosmetic
pharmaceutical
sunscreens.
Some
these
available,
non-toxic,
safer
for
use,
considerable
protective
properties
less
effects.
Plant-based
such
flavonoids
can
absorb
UVA
UVB
rays
possess
antioxidant,
anticarcinogenic,
anti-inflammatory
contribute
photoprotection.
Apart
from
flavonoids,
other
certain
vegetable
oils,
carotenoids,
stilbenes,
ferulic
acid
also
UV-absorbing
properties.
vitamins
might
be
beneficial
protection
their
antioxidant
activity.
Therefore,
aim
this
research
was
gain
insight
into
potential
replace
or
reduce
amount
conventional
filters,
based
recent
research.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(11), P. 5862 - 5862
Published: May 28, 2024
Nanotechnology
is
revolutionizing
fields
of
high
social
and
economic
impact.
such
as
human
health
preservation,
energy
conversion
storage,
environmental
decontamination,
art
restoration.
However,
the
possible
global-scale
application
nanomaterials
raising
increasing
concerns,
mostly
related
to
toxicity
materials
at
nanoscale.
The
possibility
using
in
cosmetics,
hence
products
aimed
be
applied
directly
body,
even
just
externally,
strongly
debated.
Preoccupation
arises
especially
from
consideration
that
are
synthetic
origin,
often
seen
"artificial"
their
effects
unpredictable.
Melanin,
this
framework,
a
unique
material
since
nature
it
plays
important
roles
specific
cosmetics
cover,
photoprotection
hair
skin
coloration.
Moreover,
melanin
present
form
nanoparticles,
clearly
observable
ink
some
animals,
like
cuttlefish.
artificial
nanoparticles
share
same
biocompatibility
natural
ones
chemical
photochemical
properties.
Melanin
nanocosmetic
agent,
but
its
actual
still
under
development,
also
because
regulatory
issues.
Here,
we
critically
discuss
most
recent
examples
biomimetic
highlight
requirements
future
steps
would
improve
melanin-based
view
applications
everyday
market.
Antioxidants,
Journal Year:
2025,
Volume and Issue:
14(3), P. 274 - 274
Published: Feb. 26, 2025
Exposure
to
ultraviolet
(UV)
radiation
is
a
major
contributor
skin
injury,
including
sunburn,
photoaging,
and
augmented
risk
of
cancer,
primarily
through
the
generation
reactive
oxygen
species
(ROS)
that
induce
oxidative
stress.
Rosmarinic
acid
(RA),
natural
phenolic
compound
with
antioxidant
several
other
biological
properties,
has
shown
promise
in
mitigating
such
damage
when
incorporated
into
sunscreens.
We
evaluated
RA's
possible
interactions
potential
enhance
efficacy
three
worldwide
known
UVB
filters-ethylhexyl
methoxycinnamate
(EHMC),
octocrylene
(OCT),
ethylhexyl
salicylate
(EHS).
The
performance
sunscreens
without
RA
(0.1%
w/w)
was
analyzed
vitro
vivo
photoprotective
assessments.
HPLC-TBARS-EVSC
(high-performance
liquid
chromatography-thiobarbituric
substances-ex
stratum
corneum)
protocol,
which
quantified
stress
reduction
human
corneum,
also
used.
assays
showed
had
distinct
levels
filters.
When
associated
EHMC,
exclusively
acted
range
(SPF-enhancing
effect).
Remarkably,
for
EHS,
contributed
higher
profile
total
UV
spectrum.
OCT-RA
sample
reached
highest
critical
wavelength
value
parallelly
OCT,
boosting
SPF
by
more
than
157%
comparison
OCT.
However,
its
not
affected
addition,
being
comparable
EHS-RA.
Furthermore,
protocol
highlighted
ability
reduce
lipid
peroxidation,
exhibiting
most
notable
protective
effect.
These
findings
underscore
as
multifunctional
additive
sunscreen
systems,
enhancing
both
photoprotection
mitigation.
Cosmetics,
Journal Year:
2025,
Volume and Issue:
12(1), P. 10 - 10
Published: Jan. 15, 2025
Exposure
to
ultraviolet
(UV)
radiation
from
the
sun
significantly
damages
skin,
leading
premature
aging,
hyperpigmentation,
and
oxidative
stress
that
disrupts
skin
homeostasis.
UV
increases
production
of
reactive
oxygen
species
(ROS),
accelerating
deterioration.
Although
sunscreens
remain
primary
method
for
protection,
chemical-based
formulations
are
often
associated
with
side
effects,
such
as
allergic
reactions
acne.
To
address
these
concerns,
inclusion
natural
ingredients
in
sunscreen
has
gained
attention.
Curcumin,
an
active
compound
found
turmeric
(Curcuma
longa)
Java
xanthorrhiza),
is
well-known
its
antioxidant
anti-inflammatory
properties.
This
review
explores
potential
curcumin
a
ingredient
enhancing
Sun
Protection
Factor
(SPF)
products.
A
systematic
literature
was
conducted,
analyzing
200
articles
sourced
Google
Scholar
PubMed
using
keywords
“Curcumin”,
“Curcuma”,
“Antioxidant”,
“Anti-Inflammatory”,
“Sun
Factor”.
Studies
unrelated
protection
were
excluded.
The
findings,
presented
tabular
form,
indicate
Curcuma
exhibit
significant
enhance
SPF
values
due
their
antioxidant,
anti-inflammatory,
UV-absorbing
Additionally,
may
aid
repair
following
UV-induced
damage.
However,
specific
concentration
various
remains
unknown,
further
research
necessary
determine
optimal
use.
Consideration
additional
excipients
also
required
maximize
efficacy.
In
conclusion,
demonstrates
considerable
promise
sustainable
effective
protecting
radiation,
offering
safer
alternative
conventional
sunscreens.
Applied Sciences,
Journal Year:
2025,
Volume and Issue:
15(9), P. 4707 - 4707
Published: April 24, 2025
Oxybenzone,
a
common
sunscreen
ingredient,
has
been
widely
detected
in
various
environmental
matrices,
posing
significant
ecological
and
health
risks.
The
present
study
demonstrates,
for
the
first
time,
capacity
of
Pleurotus
djamor
to
degrade
oxybenzone
vitro
cultures.
After
14
days
mycelial
incubation,
concentrations
medium
decreased
from
25
mg
1.5394
±
0.095
mg.
final
amount
mycelium
after
lyophilization
was
6.2067
0.2459
Furthermore,
addition
significantly
reduced
biomass
growth
2.510
0.6230
g
1.4697
0.0465
g.
transformation
products
dry
were
assessed
identified
using
UPLC-Q-tof
based
on
monoisotopic
molecular
mass
fragmentation
spectra.
In
processes
initiated
by
P.
djamor,
mainly
acylated
derivatives
formed.
Additionally,
compounds
with
thiol
amino
groups
identified.
Alterations
antioxidant
profiles
(L-tryptophan,
6-methyl-D,L-tryptophan,
p-hydroxybenzoic
acid,
ergosterol,
lovastatin,
phenylalanine,
ergothioneine)
response
exposure
observed.
Our
findings
reveal
changes
levels
inhibition,
underscoring
potential
toxicological
risks
associated
oxybenzone.
observed
reduction
concentration
highlights
as
an
effective
environmentally
friendly
strategy
mitigating
this
pollutant.
Journal of Environmental Science and Health Part C,
Journal Year:
2025,
Volume and Issue:
43(2), P. 184 - 207
Published: April 3, 2025
The
cosmetic
and
personal
care
product
(PCP)
industries
have
bloomed
in
the
last
ten
years.
Many
new
brand
names
established
themselves
with
various
lucrative
advertisements,
luring
youths
into
their
primary
customers.
chemicals
infused
daily
day-night
creams
or
shampoo
conditioners
been
as
Endocrine
Disrupting
Chemicals
(EDC).
unseen
side
of
coin
has
flipped
this
article
an
attempt
to
relate
rising
infertility
issue
these
products.
study
aims
explore
potential
adverse
effects
risk
assessment
EDCs
cosmetics
products,
which
highlights
a
thorough
review
indicate
whether
such
parabens,
phthalates,
UV
filters
are
safe
for
reproductive
physiology.
may
cause
severe
negative
impacts
on
systems
both
males
females
include
problems
polycystic
ovarian
syndrome,
hypospadias,
cryptorchidism,
cancer,
endometriosis,
poor
sperm
quality.
Despite
widespread
usage
purchase
products
present
world,
little
research
conducted
possible
health.
Consequently,
further
in-depth
needs
be
performed
field
better
understanding
risks
caused
by
EDCs.