Role of T Helper 1 in COVID-19 Pathogenesis: Foe or Friend DOI Open Access
Mehdi Yolmeh, Reza Ahmadi, Asyeh Yolmeh

et al.

International Journal of Enteric Pathogens, Journal Year: 2023, Volume and Issue: 11(4), P. 140 - 150

Published: Nov. 30, 2023

Cytokines produced by T helper cells (Th cells) have essential roles in the body’s defense against viruses. Inadequate and high levels of specific cytokines can side effects. This literature review article discusses mechanisms Th1 responses SARS-CoV-2 sheds light on pivotal role various inflammatory markers COVID-19-related complications. The latest literary works relevant to this study were carefully chosen evaluated. Extensive searches conducted across multiple databases, such as Scopus, PubMed, Google Scholar, ScienceDirect. After evaluating existing literature, it has been observed that unregulated immune result heightened inflammation. Recent studies provided proof occurrence cytokine storms significantly contribute severity COVID-19, ultimately resulting multi-organ failure loss life. Factors influence cell response its impact COVID-19 include timing response, pre-existing conditions, viral load, genetic susceptibility. Ultimately, effectively managing storm, we potential greatly reduce number deaths caused virus.

Language: Английский

Role of T Helper 1 in COVID-19 Pathogenesis: Foe or Friend DOI Open Access
Mehdi Yolmeh, Reza Ahmadi, Asyeh Yolmeh

et al.

International Journal of Enteric Pathogens, Journal Year: 2023, Volume and Issue: 11(4), P. 140 - 150

Published: Nov. 30, 2023

Cytokines produced by T helper cells (Th cells) have essential roles in the body’s defense against viruses. Inadequate and high levels of specific cytokines can side effects. This literature review article discusses mechanisms Th1 responses SARS-CoV-2 sheds light on pivotal role various inflammatory markers COVID-19-related complications. The latest literary works relevant to this study were carefully chosen evaluated. Extensive searches conducted across multiple databases, such as Scopus, PubMed, Google Scholar, ScienceDirect. After evaluating existing literature, it has been observed that unregulated immune result heightened inflammation. Recent studies provided proof occurrence cytokine storms significantly contribute severity COVID-19, ultimately resulting multi-organ failure loss life. Factors influence cell response its impact COVID-19 include timing response, pre-existing conditions, viral load, genetic susceptibility. Ultimately, effectively managing storm, we potential greatly reduce number deaths caused virus.

Language: Английский

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