Lecture notes in computer science, Journal Year: 2023, Volume and Issue: unknown, P. 504 - 514
Published: Jan. 1, 2023
Language: Английский
Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(10), P. 2777 - 2777
Published: May 9, 2024
Myopia is a common refractive error that affects large proportion of the population. Recent studies have revealed alterations in choroidal thickness (ChT) and blood flow (ChBF) play important roles progression myopia. Reduced ChBF could affect scleral cellular matrix remodeling, which leads to axial elongation further myopia progression. As ChT be used as potential biomarkers for myopia, several recent treatments targeted ChBF. Our review provides comprehensive overview literature on relationship between We also highlight importance an biomarker This summary has significant implications development novel strategies preventing treating
Language: Английский
Citations
11
Eye and Vision, Journal Year: 2023, Volume and Issue: 10(1)
Published: Sept. 15, 2023
Myopia control interventions, such as defocus incorporated multiple segments (DIMS) spectacle lenses, have been adopted in school-aged children to reduce the prevalence of myopia and its complications. This study aimed investigate effect DIMS lenses on subfoveal choroidal thickness (SfChT) over a period two years, response myopic is crucial factor exploring potential predicting progression.This involved secondary analysis our previous randomized clinical trial. Myopic aged 8-13 years were recruited two-year investigating progression. The treated group received (n = 78), while was with pair single vision (SV) 80). SfChT monitored at 1 week, 1, 3, 6, 12, 18 24 months post lens wear using spectral-domain optical coherence tomography custom made auto-segmentation algorithm utilizing convolutional neural networks.SfChT increased significantly after one week compared those wearing SV (adjusted mean change relative baseline ± SEM week; vs. SV, 6.75 1.52 µm - 3.17 1.48 µm; P < 0.0001, general linear model). choroid 13.64 2.62 12 thinned (- 9.46 2.55 µm). Choroidal changes demonstrated significant negative association axial elongation both groups. three predicted AL controlling age gender.Our thickening wear, sustained period. results suggested that may help predict length year. Trial registration ClinicalTrials.gov. multi-segment lens. NCT02206217. Registered 29 July 2014, https://clinicaltrials.gov/ct2/show/study/NCT02206217.
Language: Английский
Citations
22
Survey of Ophthalmology, Journal Year: 2023, Volume and Issue: 69(3), P. 362 - 377
Published: Dec. 29, 2023
Language: Английский
Citations
15
Ophthalmic and Physiological Optics, Journal Year: 2024, Volume and Issue: 44(5), P. 963 - 976
Published: April 2, 2024
Abstract Purpose To synthesise evidence across studies on factors associated with pathologic myopia (PM) onset and progression based the META‐analysis for Pathologic Myopia (META‐PM) classification framework. Methods Findings from six longitudinal (5–18 years) were narratively synthesised meta‐analysed, using odds ratio (OR) as common measure of association. All adjusted baseline myopia, age sex at a minimum. The quality was rated Grades Recommendation, Assessment, Development Evaluation Results Five out conducted in Asia. There inconclusive an independent effect (or lack thereof) ethnicity PM onset/progression. increased greater axial length (pooled OR: 2.03; 95% CI: 1.71–2.40; p < 0.001), older 1.07; 1.05–1.09; 0.001) more negative spherical equivalent refraction, SER (OR: 0.77; 0.68–0.87; all which supported by acceptable level evidence. Fundus tessellation found to independently increase population‐based study 3.02; 2.58–3.53; although this only weak that 1.23; 1.09–1.39; 0.87; 0.83–0.92; higher education 3.17; 1.36–7.35; 0.01) progression. Other be but currently included 1.01), severity myopic maculopathy 3.61), intraocular pressure 1.62) hypertension 0.21). Conclusions Most risk/prognostic are not adequate base present (an indication remains understudied). Current exists (limited number) unmodifiable adults personalised information. More focusing uncovering modifiable imaging biomarkers warranted.
Language: Английский
Citations
5
International Journal of Ophthalmology, Journal Year: 2024, Volume and Issue: 17(5), P. 940 - 950
Published: April 24, 2024
To gain insights into the global research hotspots and trends of myopia.
Language: Английский
Citations
5
Asia-Pacific Journal of Ophthalmology, Journal Year: 2024, Volume and Issue: 13(5), P. 100107 - 100107
Published: Sept. 1, 2024
To describe choroidal thickness measurements using a sequential deep learning segmentation in adults who received childhood atropine treatment for myopia control.
Language: Английский
Citations
3
Computers in Biology and Medicine, Journal Year: 2025, Volume and Issue: 191, P. 110236 - 110236
Published: April 19, 2025
Language: Английский
Citations
0
Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104628 - 104628
Published: May 1, 2025
Based on optical coherence tomography angiography (OCTA), we investigate the effects of posterior scleral reinforcement surgery fundus structure and function in patients with high myopia. Retrospective clinical study. Forty cases (41eyes) myopia who underwent at Chengdu University Traditional Chinese Medicine Affiliated Silver Eye Hospital from January 2022 to 2025 were selected. Follow-up periods included postoperative 3 months, 6 1 year. Key indicators before after compared, including best-corrected visual acuity (BCVA), axial length (AL), spherical equivalent (SE), retinal thickness (RT), choroidal (CT), Superficial capillary plexus density (SCP), deep (DCP), vascularity index (CVI), stromal (CSI). The study 40 (41 eyes), comprising 9 male (9 eyes) 31 female (32 a mean age 42.05 ± 18.71 years.At last follow-up, showed significantly shortened AL (P<0.001), improved BCVA (P<0.05), increased CT (P<0.05).SCP also exhibited significant increases (P<0.05). Additionally,CVI CSI elevation This demonstrates that achieves stabilization through mechanical reinforcement, mitigates vitreous traction forces retina choroid, enhances acuity, improves choroidoretinal microcirculation, optimizes architecture.
Language: Английский
Citations
0
Frontiers in Cell and Developmental Biology, Journal Year: 2023, Volume and Issue: 11
Published: March 17, 2023
Aim: Myopia is a common chronic eye disease, this study to investigate the effects of exogenous retinoic acid (RA) on intraocular parameters, especially choroidal thickness (CT) and retinal (RT), in guinea pigs with form deprivation myopia (FDM). Methods: A total 80 male were divided randomly into 4 groups: Control, FDM, FDM + RA, Citral groups. The RA group was given 24 mg/kg dissolved 0.4 mL peanut oil; citral 445 other two groups oil. After weeks, refractive error (RE), axial length (AL), pressure (IOP) all measured, parameters RT CT obtained using enhanced depth imaging optical coherence tomography (EDI-OCT). Results: both RE AL increased, smaller than those Control (p < 0.05). Only IOP right increased significantly compared: > group. Compared left among groups, less that Moreover, greater three 0.0001). There no significant difference In contrast results, results eyes showed statistically differences Conclusion: participates progression as regulatory factor. Exogenous can increase RE, AL, pigs, might aggravate thinning pigs. inhibit these changes, but not affect choroid.
Language: Английский
Citations
4
International Journal of Retina and Vitreous, Journal Year: 2024, Volume and Issue: 10(1)
Published: Feb. 5, 2024
Abstract Background High myopia represents a health issue and leads to the development of complications that threaten vision. The study macular changes in high patients has undergone great advances with updated technology via new spectral optical coherence tomography (OCT) Optical angiography (OCTA). Most related studies have focused on adults additional need investigate children adolescents. This aimed evaluate structure by OCT vessel density adolescents OCTA. Methods A cross-sectional comparative study. population was divided into two groups: group 1 (4–11 years) 2 (12–18 years). results were comparable those control same age group. groups examined OCTA thickness superficial deep capillary plexuses. Results measurements revealed central significantly lower than measured 220.91 ± 27.87 μm 258.23 17.26 μm, respectively, ( P < 0.0001). However, 236.32 27.76 247.09 16.81 difference not statistically significant = 0.09). parafoveal perifoveal quadrants myopic 0.0001) matched controls. densities plexuses age-matched controls both few segment exceptions 1. FAZ wider emmetropes 0.02). controls, but significant, 0.75). Conclusion thinner less FAZ.
Language: Английский
Citations
1