The Inflammation‐Initiating and Resolving Mechanisms and Oxidation: Could Periodontal Therapy and Nutritional Strategy Improve the Systemic Health? A Narrative Review

Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(3)

Published: March 1, 2025

ABSTRACT Periodontitis (PDS) is one of the most common and crippling systemic diseases. It a chronic inflammatory condition that leads to loss periodontal attachment, resulting in tooth loss. In addition its effects on oral health nutrition, PDS closely linked other conditions such as diabetes mellitus (DM), cardiovascular diseases (CVD), rheumatoid arthritis (RA). The active role inflammation oxidation health, well their relationship with therapy, has been investigated. This review explores evidence how therapy dietary lifestyle can help reduce inflammation, limit oxidation, prevent related pathologies. Nonsurgical (NSPT) nutrition have extensively discussed potential contributors positive clinical outcomes by resolving pathogenic pathways. NSPT, foods, supplements represent therapeutic strategies address underlying mechanisms at various stages. A key finding from this treatment, conjunction nutritional counseling, improve PDS, DM, CVD, RA. However, for composition be effective, they should integrated into sustainable, long‐term lifestyle.

Language: Английский

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Periodontal Disease in Saudi Arabia: A Systematic Review of Prevalence and Associated Risk Factors

Diagnostics, Journal Year: 2025, Volume and Issue: 15(7), P. 812 - 812

Published: March 22, 2025

Background/Objectives: The oral health disorder periodontal disease is widespread around the world and has a public dimension. This study aimed to perform systematic review an appraised analysis that looks at both prevalence diversity of risk factors associated with in Saudi Arabia. It places particular focus on subgroup analyses pooled estimates identify certain populations could be described as high risk. Methods: Several databases, including PubMed, Scopus, Google Scholar, were used conduct present review. search was designed relevant studies published from 1980 2023. Both quantitative qualitative included. Subgroup meta-analyses performed using random-effects model calculate rates. evaluated three criteria focused bias. Finally, authors created narrative synthesis findings for ease understanding. Results: overall 46.2% (95% CI: 40.5-51.8), heterogeneity (I2 = 85%). identified obese adults having highest this condition (71.3%), individuals diagnosed diabetes also displayed significantly (52.1%). Adolescents aged 15-19 years had age-specific 8.6%, which lower than other age groups analyzed. Poor hygiene, tobacco use, diabetes, obesity have been recognized disease. Conclusions: substantial burden Arabia, especially among high-risk groups, such diabetic adults, cannot overstated. Our initiatives need these individuals, who are likely periodontally systemically compromised, provide lifestyle modification counseling hygiene education them, well routinize their dental care way minimizes chances becoming compromised.

Language: Английский

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Photobiomodulation and the oral-gut microbiome axis: therapeutic potential and challenges

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: April 9, 2025

This Perspective article explores the challenges associated with direct application of photobiomodulation (PBM) to gut and presents a novel hypothesis for indirect health modulation through oral microbiome alteration. Given difficulties in delivering PBM effectively deep gastrointestinal tissues, an alternative approach involves targeting microbiome, which has demonstrated relationship microbiome. Research indicates that applied cavity could selectively alter microbial composition. alteration may, via oral-gut axis, indirectly impact health. hypothesis, supported by preliminary studies, suggests offer promising non-invasive strategy managing gut-related disorders. Furthermore, there may be link between brain diseases. proximity brain, PBM-induced changes microbiota help prevent neurological However, further investigation is necessary comprehensively elucidate underlying mechanisms therapeutic implications this approach.

Language: Английский

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Geriatric Population’s Awareness and Attitudes toward Edentulism and Rehabilitation - Influencing Factors and Their Interrelationships: A Cross-sectional Study

Journal of The Indian Academy of Geriatrics, Journal Year: 2025, Volume and Issue: 21(1), P. 34 - 39

Published: Jan. 1, 2025

Abstract Introduction: This cross-sectional study examines the awareness and attitudes of India’s geriatric population toward edentulism prosthetic rehabilitation. Conducted from June to August 2024 across diverse regions, 199 participants aged over 60 years were surveyed using a self-administered questionnaire. Results showed that 88.9% recognized importance tooth replacement, with most favoring removable prostheses for cost reasons. The main barriers financial constraints (38.7%), fear (26.1%), lack information (15.6%). Notably, 83.4% expressed interest in learning more about options. emphasizes need improved oral health education accessibility dental care elderly population. Aims Objectives: To assess rehabilitation various educational socioeconomic backgrounds India correlate them contributing factors. Materials Methods: A questionnaire, pilot-tested revised, was distributed participants. It assessed awareness, prosthetics, treatment. Data collected on sociodemographic details analyzed statistically. Results: About believed replacement important, but fixed implants low. Removable preferred due cost, (38.7%) being largest barrier. Conclusions: Although treatments is growing, informational limit access. Targeted interventions are necessary improve service accessibility.

Language: Английский

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The Global Burden of Periodontal Disease: A Narrative Review on Unveiling Socioeconomic and Health Challenges

International Journal of Environmental Research and Public Health, Journal Year: 2025, Volume and Issue: 22(4), P. 624 - 624

Published: April 16, 2025

Periodontal disease is a prevalent chronic inflammatory condition that impacts over billion people worldwide, leading to substantial tooth loss, reduced quality of life, and heightened systemic health risks. This narrative review synthesizes current evidence regarding the global burden periodontal disease, its established associations with conditions including cardiovascular diabetes, adverse pregnancy outcomes, respiratory infections, neurodegenerative disorders, significant socioeconomic implications. The focused on following research question: What how do implications necessitate integrated public strategies? A structured search PubMed, Scopus, WHO databases from 2000 2024 was conducted identify relevant literature using key terms, “periodontal disease”, “global burden”, “systemic inflammation”, “public strategies”. Out 312 initially identified articles, 175 satisfied inclusion criteria for final synthesis. findings underscore significance as modifiable risk factor various noncommunicable diseases, influence healthcare disparities progression, critical necessity strategies mitigate consequences. concludes coordinated policy reform, system integration, enhanced efforts are crucial mitigating advancing equity.

Language: Английский

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