The Advancement of Appendicitis in Children in the Pre-Pandemic and the Pandemic Year

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(20), P. 6137 - 6137

Published: Oct. 15, 2024

The COVID-19 pandemic affected the health of millions people, both directly through infection and indirectly delayed diagnosis treatment non-COVID-19 illnesses. aim this study was to check impact on appendicitis in children.

Language: Английский

Evaluating the Risk of Cardiovascular Adverse Events and Appendicitis After COVID-19 Diagnosis in Adults in the United States: Implications of the Start of Follow-Up

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 6, 2024

Abstract Purpose This study evaluated the association between coronavirus disease 2019 (COVID-19) diagnosis and adverse events (AEs), including cardiovascular AEs appendicitis, in US adults before introduction of COVID-19 vaccines. Real-world studies after suggest that diagnoses frequently occur on same day may be a source bias. Methods Cohort self-controlled risk interval (SCRI) designs were used 2 administrative claims data sources—Merative™ MarketScan® (ages 18-64 years) Medicare ≥ 65 years). included stroke (nonhemorrhagic hemorrhagic), acute myocardial infarction, myocarditis/pericarditis, deep vein thrombosis, pulmonary embolism (PE), disseminated intravascular coagulation (DIC), unusual-site common-site thrombosis with thrombocytopenia syndrome, appendicitis. In cohort analyses, weighted hazard ratios (HRs) 95% confidence intervals (CIs) compared matched comparators. SCRI analysis, relative incidences (RIs) CIs reference windows within individuals. Analyses performed starting follow-up Time 0 Day 1. Results For AEs, all estimates 1 above 1.0 both sources. strongest associations for inpatient PE databases: MarketScan, HR=8.65 (95% CI, 6.06-12.35), HR=3.06 2.88-3.26). MarketScan was DIC: RI=32.28 17.06-61.09) myocarditis/pericarditis: RI=4.53 3.89-5.27). diagnosed concurrently (ie, 0) common; follow-up/risk resulted higher RIs, as well HRs some AEs. However, (eg, stroke) more common comparator group resulting lower HRs. Conclusion had moderate to strong weak or inconsistent although varied by design methodology.

Language: Английский

Clinical management and complications of acute appendicitis in 3 children with SARS-CoV-2 infection: Case report

Medicine, Journal Year: 2024, Volume and Issue: 103(43), P. e40105 - e40105

Published: Oct. 25, 2024

Rationale: Sporadic cases of acute appendicitis (AA) in children with SARS-CoV-2 infection were still recorded at the end COVID-19 pandemics. We consider that analyses clinical courses and outcomes is useful to improve management such setting a general hospital. Patient concerns: #1 was 14-year-old girl who presented nausea, right lower quadrant (RLQ) pain, myalgia, ad low-grade fever for 24 hours. #2 7-year-old boy 3-day history abdominal nausea vomiting, lasting 4 days. # 3 16-year-old RLQ 7 Diagnoses: The patients diagnosed based on picture, labs ultrasound (US) findings. SARS-CoV- 2 using rapid antigen test performed admission. Interventions: started i.v. Ceftriaxone Metronidazole, antalgics i.v . fluids Appendectomy day after admission 1 #2, 48 hours patient #3. Outcomes: had no complications discharged postoperative (POD) #5. developed cecal fistula POD #4 which treated conservatively Ertapenem, fluids, local placement colostomy bag. closed spontaneously #12. He #17. #3 abscess 6 required laparoscopic surgical drainage abscess. She another days (POD #12). No ICU admission, steroids, or supplemental O use during their hospitalization. There late readmissions these patients. Lessons: AA positive similar course negative cases. Compliance previously established protocols outcome. parents should bring sick child early hospital order avoid related delayed presentation not itself.

Language: Английский