Optimizing Immunotherapy: The Synergy of Immune Checkpoint Inhibitors with Artificial Intelligence in Melanoma Treatment
Mohammad Saleem,
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Abigail E. Watson,
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Aisha Anwaar
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et al.
Biomolecules,
Journal Year:
2025,
Volume and Issue:
15(4), P. 589 - 589
Published: April 16, 2025
Immune
checkpoint
inhibitors
(ICIs)
have
transformed
melanoma
treatment;
however,
predicting
patient
responses
remains
a
significant
challenge.
This
study
reviews
the
potential
of
artificial
intelligence
(AI)
to
optimize
ICI
therapy
in
by
integrating
various
diagnostic
tools.
Through
comprehensive
literature
review,
we
analyzed
studies
on
AI
applications
immunotherapy,
focusing
predictive
modeling,
biomarker
identification,
and
treatment
response
prediction.
Key
findings
highlight
efficacy
improving
outcomes.
Machine
learning
models
successfully
identified
prognostic
cytokine
signatures
linked
nivolumab
clearance.
The
combination
with
RNAseq
analysis
had
for
development
personalized
ICIs.
A
machine
learning-based
approach
was
able
assess
risk-benefit
ratio
prediction
immune-related
adverse
events
(irAEs)
using
electronic
health
record
(EHR)
data.
Deep
algorithms
demonstrated
high
accuracy
tumor
microenvironment
analysis,
including
region
identification
lymphocyte
detection.
AI-assisted
quantification
tumor-infiltrating
lymphocytes
(TILs)
proved
prognostically
valuable
primary
anti-PD-1
metastatic
cases.
Integrating
multiple
modalities,
such
as
CT
imaging
laboratory
data,
modestly
enhanced
performance
1-year
survival
advanced
cancers
treated
immunotherapy.
These
underscore
AI-driven
approaches
refine
prediction,
stratification
While
promising,
clinical
validation
implementation
challenges
remain.
Language: Английский
Advancements and Challenges in Personalized Therapy for BRAF-Mutant Melanoma: A Comprehensive Review
Abdulaziz Shebrain,
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Omer A. Idris,
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Ali Jawad
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et al.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(18), P. 5409 - 5409
Published: Sept. 12, 2024
Over
the
past
several
decades,
advancements
in
treatment
of
Language: Английский
Investigating Skin Cancer Diagnosis Using a Webcam-based Microcontroller System
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
19(1), P. 37 - 47
Published: April 3, 2024
Skin
cancer
can
spread
fast
to
nearby
tissue
and
other
parts
of
the
human
body
if
it's
not
diagnosed
early.
Most
are
curable
only
skin
is
found
treated
in
early
stages.
Therefore,
essential
seek
a
casual
way
diagnosis.
This
paper
assesses
prototype
system
for
detection
using
an
Arduino
with
ArduCam
Mega
5MP,
benchmarked
against
smartphone
Bandpass
filters
capture
images
at
red
(650
nm),
green
(532
blue
(450
nm)
wavelengths,
measuring
reflectance
values.
The
approach
aims
quantitatively
determine
melanin,
oxyhemoglobin,
deoxyhemoglobin
levels,
aiding
various
lesions'
Evaluation
involves
comparing
pixel
values
taken
by
smartphones
3D
mesh
grid.
Applying
modified
Lambert-Beer
law
moles,
pimples,
scars,
scabs,
traces
predicts
relative
levels
components.
shows
87%
match
standard,
demonstrating
high
reliability.
Further
study
might
be
needed
clarify
confirmation
clinical
cases.
Language: Английский
Artificial Intelligence and Machine Learning in Diagnostics and Treatment Planning
Ankur Tak
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Journal of Artificial Intelligence & Cloud Computing,
Journal Year:
2023,
Volume and Issue:
unknown, P. 1 - 6
Published: March 31, 2023
This
paper
explores
how
machine
learning
(ML)
and
artificial
intelligence
(AI)
are
transforming
treatment
planning
diagnosis
in
the
healthcare
industry.
These
technologies,
which
make
use
of
sophisticated
algorithms
computer
models,
have
shown
great
promise
for
improving
precision,
effectiveness,
customized
nature
medical
therapies.
When
using
AI
ML
diagnostics,
large
datasets
from
patient
records
to
images
must
be
analyzed.
technologies
facilitate
prevention
by
enabling
rapid
exact
illness
identification
through
deep
pattern
recognition
algorithms.
Predictive
modeling
also
makes
it
possible
anticipate
a
disease
will
progress,
preemptive
plans
possible.
play
major
role
optimizing
therapeutic
techniques
during
planning.
aid
development
best
based
on
distinct
responses,
genetic
characteristics,
other
pertinent
aspects
evaluating
data
specific
each
patient.
promotes
more
patient-focused
paradigm
minimizing
side
effects
increasing
efficacy.
The
study
looks
at
difficulties
moral
issues
surrounding
application
medicine.
Notwithstanding
encouraging
results,
is
crucial
underline
necessity
strong
validation,
openness,
responsible
technology
deployment
order
guarantee
these
technologies'
trustworthy
contexts.
In
summary,
combination
has
enormous
potential
transform
diagnosis,
presenting
hitherto
unheard-of
chances
precision
medicine
better
outcomes.
As
develop
further,
way
they
fit
into
clinical
workflows
might
completely
change
delivered
usher
new
era
tailored,
data-driven
treatments.
Language: Английский