Post COVID-19 and Long COVID Symptoms in Otorhinolaryngology—A Narrative Review

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(2), P. 506 - 506

Published: Jan. 14, 2025

Post/Long COVID (syndrome) is defined as a condition with symptoms persisting for more than 12 weeks after the onset of SARS-CoV-2 infection that cannot be explained otherwise. The prevalence self-reported otorhinolaryngological high. aim this review was to analyze current literature regarding actual prevalence, knowledge etiopathology, and evidence-based treatment recommendations otorhinolaryngology-related symptoms. A systematic search articles published since 2019 in PubMed ScienceDirect performed resulted 108 articles. These were basis formed comprehensive series consented therapy statements on most important Otorhinolaryngological did not appear isolated but part multi-organ syndrome. Self-reported often confirmed by objective testing. estimated anosmia, dysgeusia, cough, facial palsy, hoarseness/dysphonia, acute hearing loss, tinnitus, vertigo/dizziness about 4%, 2%, 4-19%, 0%, 17-20%, 8%, 20%, 5-26%, respectively. There are manifold theoretical concepts etiopathology different symptoms, there no clear proof. This certainly contributes fact effective specific option any mentioned. Healthcare pathways must established so can recognized evaluated otorhinolaryngologists provide counseling. would also help establish selectively include patients clinical trials investigating therapeutic concepts.

Language: Английский

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COVID-19 and Disabilities: Impact and the Emergence of Long COVID

Published: Jan. 1, 2025

Language: Английский

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Neurological Impact of SARS-CoV-2 Changing Variants: A 4-Year DW-MRI Study on Olfactory and Taste-Related Brain Regions

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 3164 - 3164

Published: March 29, 2025

Neurological symptoms such as impaired smell and taste have been recognized hallmark manifestations of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. This study investigates quantifies microstructural changes in the white matter olfactory bulb taste-related brain regions (frontal operculum, insular cortex parietal operculum) using diffusion-weighted magnetic resonance imaging (DW-MRI). Apparent diffusion coefficient (ADC) values were measured patients with confirmed disease 2019 (COVID-19) at onset anosmia ageusia (24 patients, scanned between March December 2020), 1 month post-infection (20 subjects) 36 months participants). ADC analyzed over time compared to normal ranges (calculated retrospectively from 979 pre-pandemic patients) those infected 2024 strain SARS-CoV-2 (27 patients). The results revealed significantly elevated targeted regions, a peak infection, followed by decline post-infection, return near-normal levels 3 years later. In contrast, COVID-19 variant demonstrated reduced virus-related alterations microstructure 2020 strain. These findings highlight potential DWI non-invasive tool for elucidating molecular mechanisms underlying dysfunction patients.

Language: Английский

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Impact of COVID-19 on brain connectivity and rehabilitation outcome after stroke

Heliyon, Journal Year: 2024, Volume and Issue: 10(14), P. e34941 - e34941

Published: July 1, 2024

Language: Английский

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Morphometric Brain Alterations in Patients with Depression after COVID-19: A Comparative Study with Non-COVID-19 Depression and Healthy Controls

Neurochemical Journal, Journal Year: 2024, Volume and Issue: 18(4), P. 855 - 866

Published: Dec. 1, 2024

Language: Английский

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