Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 6, 2025

Since its emergence in 2019, COVID-19 has continued to pose significant threats both the physical and mental health of global population, as well healthcare systems worldwide (Raman et al., Eur Heart J 43:1157–1172, 2022). Emerging evidence indicates that may lead post-acute syndrome (PACS) with cardiovascular implications, potentially driven by factors such ACE2 interaction viruses, systemic inflammation, endothelial dysfunction. However, there remains a limited amount research on manifestations PACS, which delay development optimal treatment strategies for affected patients. Therefore, it is crucial investigate prevalence sequelae patients determine whether infection acts an independent risk factor these outcomes. This meta-analysis adhered PRISMA guidelines was registered PROSPERO (CRD42024524290). A systematic search PubMed, Embase, Cochrane Library conducted up March 17, 2024. The primary outcomes included hypertension, palpitations, chest pain, pooled effect estimate reported proportions odds ratios (ORs) 95% confidence intervals (CIs). Sensitivity subgroup analysis were performed assess robustness results identify sources heterogeneity. total 37 studies, encompassing 2,965,467 patients, analysis. Pooled from case–control studies revealed that, compared control group, ORs pain group 4.0 (95% CI: 1.6, 10.0). palpitation hypertension 3.4 1.1, 10.2) 1.7 1.8), respectively. PACS experiencing palpitation, 22% 14%, 33%), 18% 13%, 24%), 19% 12%, 31%), Our findings indicate 15% experience sequelae. Furthermore, significantly increases likelihood developing uninfected individuals. Future should prioritize investigating underlying pathological mechanisms targeted preventive management strategies. CRD42024524290.

Language: Английский

Exploring Global Demands for Integrating Social Aspects into Community Healthcare: A Literature Review

Health, Journal Year: 2024, Volume and Issue: 16(09), P. 785 - 793

Published: Jan. 1, 2024

Language: Английский

Physical development of infants born to patients with COVID-19 during pregnancy: 2 years of age

PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e18481 - e18481

Published: Nov. 12, 2024

Background SARS-CoV-2 infection during pregnancy and pandemic circumstances could negatively impact infant development. This study aimed to investigate the physical development, common pediatric illness incidence, healthcare utilization over first 2 years of life infants born COVID+ COVID- patients. Comparisons were also made with pre-pandemic. Methods is a retrospective observational at major academic health system in New York City. Participants include all birthing persons ( N = 758) without 9,345) from 03/01/2020 08/17/2022, pre-pandemic 3,221) 03/01/2017 08/17/2019, infants. Results There no differences weight, length, or head circumference curves between patients p > 0.05, repeated ANOVA). Annualized incidence occurrence similar groups. Compared infants, length (COVID-) was lower birth 9 months < 0.0001). Pandemic additionally had more adverse perinatal outcomes including increased stillbirth (0.75% vs . 0.12%, 0.0001) decreased gestational age (38.41 ± 2.71 38.68 2.55 weeks, Cohen’s d −0.10, 0.0001), birthweight (2,597 335 3,142 643 g, −1.06, (48.08 4.61 49.09 3.93 cm, −0.24, Conclusions Birthing persons’ status, profiles, affected outcomes, newborn utilization. These findings draw clinical attention need follow closely implement enrichment ensure optimal developmental outcomes.

Language: Английский