
Biomedicines, Journal Year: 2025, Volume and Issue: 13(5), P. 1097 - 1097
Published: April 30, 2025
Background: Post-COVID-19 syndrome (PCS) is defined as the persistence of symptoms 3 months after acute SARS-CoV-2 infection. The long-term prevalence and clinical progression PCS has not been established. Our aim was to investigate in patients, explore degree physical activity, according fatigue severity score, analyze its association with basic cardio-pulmonary exercise testing (CPET) parameters. Methods: A total 192 subjects history SARSCoV-2 infection were included. They filled Chronic Fatigue Syndrome Questionnaire (CFSQ) divided into symptomatic asymptomatic groups. Forty-seven had persistent post-COVID complaints—reduced capacity, fatigue, dyspnea, sleep disturbances, muscle pain. CPET performed pathophysiological parameters different groups compared. Results: Subjects two groups—mild (20) moderate–severe (27), depending on CFSQ score; forty-eight without complaints served a control group. average period between illness study 1028 ± 214 days. more during (73.6% vs. 24.8% 17.4%), compared mild/asymptomatic. rate perceived effort subjective did correspond workload, heart, or breathing These unable reach anaerobic threshold, mild/asymptomatic (51.8% 25%, 12.5%). Patients showed lower peak VO2 (24.13 6.1 mL/min/kg 26.73 5.9 mL/min/kg, 27.01 6.3 mL/min/kg), subjects. Conclusions: Long-term still present up 24% general population, than thirty episode. It characterized by increased perception symptom burden diminished aerobic metabolism. third exhibit cardio-respiratory fitness, independently from symptoms.
Language: Английский