Dynamic effects of fixed orthodontic treatment on oral health and oral microbiota: a prospective study DOI Creative Commons
Mei Zhao,

Chaoran Yu,

Chengjun Su

et al.

BMC Oral Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 21, 2024

This prospective clinical study examined the effects of fixed orthodontic appliances on oral hygiene and assessed changes in microflora structure patients using high-throughput sequencing technology. A total 45 undergoing initial treatment were recruited from three hospitals Beijing, China. Clinical parameters habits questionnaire recorded at pre-treatment (T0) a 6-month follow-up (T1). Saliva samples collected for DNA extraction, PCR amplification, 16S rRNA gene sequencing, bioinformatics analysis. Microbial diversity structural abundance evaluated. After six months treatment, patients' daily brushing frequency increased (P ≤ 0.01), while plaque index debris decreased. 3,344,549 valid tags obtained 90 saliva samples. six-month follow-up, microbial significantly. High-throughput identified 3,662 amplicon sequence variants (ASVs), with dominant phyla being Proteobacteria, Bacteroidota, Firmicutes, Actinobacteriota, Fusobacteriota, Patescibacteria, Campylobacterota Spirochaetota. At phylum level, Firmicutes_C Spirochaetota T1 significantly compared to T0. During although improved, significant microbiota still observed, an increase anaerobic pathogenic bacteria that may potentially impact health.

Language: Английский

Biofilm Composition Changes During Orthodontic Clear Aligners Compared to Multibracket Appliances: A Systematic Review DOI Creative Commons
Alba Belanche Monterde, Javier Flores-Fraile, Esteban Pérez-Pevida

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(5), P. 1039 - 1039

Published: April 30, 2025

Introduction: Clear aligner treatment seems to be a good option for the periodontal patient by reason of being removable. Multibracket appliances are more difficult mantain clean and some bacteria might prefer adhere on archwire. Methodology: A systematic review was carried out using 4 electronic databases (Pubmed-Medline, Scopus, Cochrane Web Science). The selected trials included quantitative (Shannon index, Simpson relative abundances) and/or qualitative (alpha beta diversity) analysis in patients clear aligners multibracket appliances. Results: Initially, total 123 articles were found after selecting clinical trials. inclusion exclusion criteria applied two authors. Finally, 20 review. results showed that produced less dysbiosis compared However, microbiological changes observed during use. Discussion: Oral dysibiosis related with intestinal dysbiosis, inflammatory response even cancer. Firmicutes/Bacteroidetes ratio have very important role this development. Periodontitis is also bacterial disease recommended risk patients. Conclusion: obtained supra subgingival biofilm but altered treatment.

Language: Английский

Citations

0

The Impact of Orthodontic Adhesives on the Subgingival Microbiota During Early Fixed Appliance Therapy: A Pilot Study DOI Creative Commons
Krisztina Mártha, Erika Kis,

Izabella Éva Mureșan

et al.

Medicina, Journal Year: 2025, Volume and Issue: 61(5), P. 858 - 858

Published: May 7, 2025

Background and Objectives: The most common method for treating malocclusions today is fixed orthodontic therapy, during which brackets tubes are bonded to the surface of teeth, makes oral hygiene difficult maintain. Increased plaque retention, gingival bleeding, gingivitis can be diagnosed in early phases treatment. periodontal response accumulation explained by quantitative qualitative changes subgingival microbiota. aim our research was investigate microbiota that occurred within 6–8 weeks after bonding when two different adhesives were used. Materials Methods: Thirty patients followed; molar with a composite (C) fifteen cases, other they glass ionomer cementum (GIC). A microbiological sample taken from sulcus maxillary first molars at time appliance placement (T1) (T2) bonding. Bacterial DNA detection performed using micro-IDent®plus11 (Hain Lifescience GmbH, Germany) PCR (polymerase chain reaction) method. statistical analysis included McNemar’s test analyze paired binary data Fisher’s Exact Test compare prevalence each 11 bacteria T1 and, ultimately, T2 between studied groups. Bonferroni correction also applied. Results: When analyzing GIC vs. C T2, none pathogens showed significant differences. Conclusions: Given lack significance, these trends do not confirm definitive impact procedure on bacterial presence. increased presence might suggest does reduce loading Less protective effects intervention against Tannerella forsythia Eubacterium nodatum detected.

Language: Английский

Citations

0

Materials for Clear Aligners—A Comprehensive Exploration of Characteristics and Innovations: A Scoping Review DOI Creative Commons
Niccolò Cenzato,

Giada Di Iasio,

Carmen Martín Carreras‐Presas

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(15), P. 6533 - 6533

Published: July 26, 2024

Introduction: Transparent orthodontic aligners have revolutionized dentistry and orthodontics since the 1990s, offering advantages over traditional fixed appliances in terms of hygiene, comfort, aesthetics. With increasing demand for invisible treatments, clear gained popularity, prompting research into materials to enhance their efficacy performance. Materials Methods: A scoping review was conducted using electronic databases (Pubmed, Medline, Cochrane Library, Embase, Scopus) identify studies on aligner published last decade. Selection criteria focused specific dental materials, excluding those unrelated or aligners. Results: The included 11 relevant evaluating 17 different materials. such as polyvinyl chloride derivatives, thermoplastic polyurethanes (TPU), polyethylene terephthalate glycol (PETG) were commonly used. assessed mechanical, physical, chemical, optical properties, well thermoforming effects, stress decay, surface characteristics. Discussion Conclusions: Various exhibited distinct with PETG transparency flexibility, while TPU-based like Smart Track providing durability elasticity. Thermoforming affected mechanical both TPU showing decreased post-thermoforming. Polymer blending improved but variations existed among brands Clear exhibit diverse characteristics, influencing suitability use. PETG-based offer provide However, undergo changes post-thermoforming, emphasizing need further optimize material performance clinical

Language: Английский

Citations

1

Quantitative Determination of Salivary Cariogenic Bacteria in Patients With Fixed Orthodontic Appliances DOI Open Access

Fighan Hussein,

Maryam Fouad Bilal,

Tara Saleem Hamad

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 12, 2024

Background and objectives: Fixed orthodontic treatment can alter the oral environment, potentially increasing cariogenic bacteria levels. This study aimed to utilize real-time polymerase chain reaction (qPCR) quantify salivary levels of in patients undergoing with fixed appliances. Methods: case-control was conducted Erbil, Iraq, from April 2024 August 2024. One hundred participants were included by random sampling method equally divided into two groups: case group or control group. The brackets, while without current past matching age sex as Data collected via questionnaires, clinical examinations, saliva sampling. Salivary samples analyzed using PCR detect Streptococcus mutans (SM) Lactobacillus (LB) spp. Results: ranged 18 30 years, mean 23.96 ± 3.64 years. No significant differences observed between groups across most parameters, except use fluoride therapy, where demonstrated better usage (p≤0.003). Real-time results indicated a difference LB SM orthodontics (p≤0.001). However, no found decay indices such decayed, missing, filled teeth; surfaces; plaque index this study. Conclusions: quantity higher compared Despite elevated bacterial group, there groups.

Language: Английский

Citations

0

Dynamic effects of fixed orthodontic treatment on oral health and oral microbiota: a prospective study DOI Creative Commons
Mei Zhao,

Chaoran Yu,

Chengjun Su

et al.

BMC Oral Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 21, 2024

This prospective clinical study examined the effects of fixed orthodontic appliances on oral hygiene and assessed changes in microflora structure patients using high-throughput sequencing technology. A total 45 undergoing initial treatment were recruited from three hospitals Beijing, China. Clinical parameters habits questionnaire recorded at pre-treatment (T0) a 6-month follow-up (T1). Saliva samples collected for DNA extraction, PCR amplification, 16S rRNA gene sequencing, bioinformatics analysis. Microbial diversity structural abundance evaluated. After six months treatment, patients' daily brushing frequency increased (P ≤ 0.01), while plaque index debris decreased. 3,344,549 valid tags obtained 90 saliva samples. six-month follow-up, microbial significantly. High-throughput identified 3,662 amplicon sequence variants (ASVs), with dominant phyla being Proteobacteria, Bacteroidota, Firmicutes, Actinobacteriota, Fusobacteriota, Patescibacteria, Campylobacterota Spirochaetota. At phylum level, Firmicutes_C Spirochaetota T1 significantly compared to T0. During although improved, significant microbiota still observed, an increase anaerobic pathogenic bacteria that may potentially impact health.

Language: Английский

Citations

0