The role of autophagy in periodontal diseases: a bibliometric analysis from 2006 to 2023 DOI Creative Commons
Bing Zhang, Yahui Wang, Haoxiang Chang

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: May 9, 2025

Background Periodontal disease is a chronic inflammatory condition affecting the supporting structures of teeth, involving complex interactions between systemic and local immune responses. Autophagy tightly regulated cellular process that responsible for degrading recycling components, playing pivotal role in maintaining homeostasis modulating inflammation periodontal disease. In recent years, relationship these two factors has attracted attention from scholars globally. However, bibliometric analyses this field are still limited. Objectives To analyze trends research hotspots related to autophagy Methods Articles reviews examining association were retrieved Web Science Core Collection (WOSCC) on 20 June 2024. Bibliometric knowledge mapping performed using CiteSpace [6.3. R1 (64-bit) Advanced]. Results Through analysis literature published 2006 2023 disease, 341 relevant studies identified. The results indicate steady annual increase topic, with significant upward trend observed post-2015. Keyword identifies “apoptosis,” “Porphyromonas gingivalis,” “oxidative stress,” “inflammation,” “periodontitis,” “osteogenic differentiation,” “cell death,” “orthodontic tooth movement” as key hotspots. Collaboration network China leading contributor field. Document co-citation highlights several influential “double-edged sword” illustrating how alleviates oxidative stress periodontitis by removing damaged organelles, inhibiting pro-inflammatory mediators, promoting tissue repair through secretion pro-angiogenic cytokines. excessive may lead apoptosis when surpasses capacity. This study underscoring importance international collaboration high-impact journals advancing guiding future research. Conclusion Recent emerged critical mediator dual roles Therefore, early control inflammation, along exploration harness protective functions autophagy, provide directions managing

Language: Английский

The role of autophagy in periodontal diseases: a bibliometric analysis from 2006 to 2023 DOI Creative Commons
Bing Zhang, Yahui Wang, Haoxiang Chang

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: May 9, 2025

Background Periodontal disease is a chronic inflammatory condition affecting the supporting structures of teeth, involving complex interactions between systemic and local immune responses. Autophagy tightly regulated cellular process that responsible for degrading recycling components, playing pivotal role in maintaining homeostasis modulating inflammation periodontal disease. In recent years, relationship these two factors has attracted attention from scholars globally. However, bibliometric analyses this field are still limited. Objectives To analyze trends research hotspots related to autophagy Methods Articles reviews examining association were retrieved Web Science Core Collection (WOSCC) on 20 June 2024. Bibliometric knowledge mapping performed using CiteSpace [6.3. R1 (64-bit) Advanced]. Results Through analysis literature published 2006 2023 disease, 341 relevant studies identified. The results indicate steady annual increase topic, with significant upward trend observed post-2015. Keyword identifies “apoptosis,” “Porphyromonas gingivalis,” “oxidative stress,” “inflammation,” “periodontitis,” “osteogenic differentiation,” “cell death,” “orthodontic tooth movement” as key hotspots. Collaboration network China leading contributor field. Document co-citation highlights several influential “double-edged sword” illustrating how alleviates oxidative stress periodontitis by removing damaged organelles, inhibiting pro-inflammatory mediators, promoting tissue repair through secretion pro-angiogenic cytokines. excessive may lead apoptosis when surpasses capacity. This study underscoring importance international collaboration high-impact journals advancing guiding future research. Conclusion Recent emerged critical mediator dual roles Therefore, early control inflammation, along exploration harness protective functions autophagy, provide directions managing

Language: Английский

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