Decellularization techniques pave the way for tissue engineering and regenerative medicine: a narrative review

Regenerative medicine reports ., Journal Year: 2024, Volume and Issue: 1(2), P. 117 - 130

Published: Dec. 1, 2024

Decellularization refers to the removal of cellular components from animal tissues or organs via specific methods obtain an extracellular scaffold comprising matrix. Physical, chemical, and biological can be used remove organs. The obtained decellularized matrix retains both original structural framework bioactive significantly reduces immune rejection. This is ideal three-dimensional for cell growth tissue repair. Despite remarkable progress in decellularization technology, some challenges remain. For example, how achieve efficient uniform without compromising integrity bioactivity matrix, ensure that sterilization do not damage structure function improve clinical safety efficacy are important. paper delves into various decellularization, evaluation techniques matrices, their potential applications multiple fields organ regeneration, bio3D printing, disease modeling, with a special emphasis on critical role matrices as bioinks printing support adhesion differentiation, highlighting significant value technology construction complex structures. use bioscaffold better functional recovery. By optimizing processes, performance further improved advance its applications. In conclusion, application which repairing damaged tissues, customizing personalized therapeutic solutions, developing new drug testing platforms, promising. Further research expected development regenerative medicine, thereby providing patients safer more effective treatment options.

Language: Английский

Functional Foods with Modulating Action on Metabolic Risk Factors

Foods, Journal Year: 2023, Volume and Issue: 12(21), P. 4043 - 4043

Published: Nov. 6, 2023

Health-related metabolic risk factors, such as elevated blood pressure, hyperglycemia, obesity, and dyslipidemia, can lead to syndrome increased of cardiovascular disease, stroke, death [...].

Language: Английский