Food Science & Nutrition,
Journal Year:
2024,
Volume and Issue:
12(10), P. 8419 - 8431
Published: Sept. 8, 2024
Abstract
Coix
seed
is
recognized
as
a
functional
medicinal
food
due
to
its
valuable
biological
activities,
with
polysaccharides
being
the
primary
active
compounds.
In
this
study,
an
ultrasonic‐assisted
enzymatic
extraction
technique
was
employed,
and
response
surface
methodology
used
optimize
yield
of
9.55
±
0.26%.
A
novel
neutral
polysaccharide,
CSPsN‐1,
purified
molecular
weight
7.75
kDa.
CSPsN‐1
composed
arabinose,
galactose,
glucose,
xylose,
mannose
in
molar
ratios
0.48:
7.92:
86.39:
2.42:
2.79.
Its
backbone
→4)‐α‐D‐Glc
p
‐(1→
→3,4)‐α‐D‐Glc
units,
terminal
residues
α‐D‐Glc
.
vitro
experiments,
enhanced
glucose
consumption
insulin‐resistant
HepG2
cells
upregulated
GLUT4
expression
by
activating
PI3K/AKT
signaling
pathway.
These
findings
suggest
that
holds
significant
promise
ingredient
for
treating
insulin
resistance
related
metabolic
disorders.
Journal of Applied Phycology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 28, 2025
Abstract
Sea
lettuce
(
Ulva
spp.),
widely
known
for
their
fast
growth
and
accumulation
in
coastal
regions,
represent
an
abundant
sustainable
source
biomaterials.
Their
biomass,
which
often
contributes
to
"green
tides",
holds
great
potential
various
applications,
including
bioactive
compound
extraction.
This
study
focused
on
optimizing
the
extraction
of
total
phenolic
compounds
ulvan
from
spp.,
leveraging
both
promising
algae
efficiency
ultrasound-assisted
(UAE)
as
a
method.
Using
response
surface
methodology
(RSM),
optimal
conditions
were
identified
100%
equipment
amplitude
(1300
W)
unmodified
pH
5.7.
These
parameters
led
0.253
±
0.006
g
GAE
(100
DW)
−1
9.29
0.47%
yield
ulvan.
The
extracted
exhibited
remarkable
structural
properties,
high
molecular
weight
(≥
800
kDa)
intermediate
viscosity
(~
Pa
s),
alongside
stable
antioxidant
capacity.
Fourier-transform
infrared
(FT-IR)
analysis
confirmed
ulvan's
chemical
consistency,
while
vitro
assays
demonstrated
strong
cytocompatibility
immunomodulatory
activity,
reinforcing
its
biomedical
food
packaging
applications.
Archiv der Pharmazie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 9, 2024
Polysaccharides,
the
most
abundant
biopolymers
in
nature,
have
attracted
attention
of
researchers
and
clinicians
due
to
its
practicality
biomedical
pharmaceutical
sciences.
These
biomaterials
high
bioavailability
play
structural
functional
roles
living
organisms.
Polysaccharides
are
classified
into
several
groups
based
on
their
origin,
including
plant
polysaccharides
marine
(like
chitosan,
hyaluronic
acid,
dextran,
alginates,
etc.)
with
specific
applications.
possess
unique
physicochemical
(such
as
surface
groups,
solubility,
stability),
mechanical
strength
tensile),
antioxidant
activity,
biocompatibility,
biodegradability,
renewability,
non-immunogenicity)
characteristics
which
made
them
excellent
platforms
for
a
wide
variety
Ease
extraction
different
preparation
approaches
mentioned
other
potential
properties
that
further
improved
They
drug/bioactive
encapsulation
capacity
sustained/controlled
release
manner
vivo
microenvironments.
The
anti-inflammatory
immunomodulation,
stimuli-responsive
release,
passive
active
delivery
considered
features
these
indicated
practical
applications
sciences,
biosensors,
tissue
engineering,
implantation,
wound
healing,
vascular
grafting,
vaccines.
This
review
highlights
advances
polysaccharide-based
materials
Foods,
Journal Year:
2024,
Volume and Issue:
13(19), P. 3196 - 3196
Published: Oct. 8, 2024
Enzymes
play
a
vital
role
in
the
food
industry,
where
they
act
as
natural
catalysts
to
improve
production
processes,
enhance
quality,
and
increase
efficiency
[...].
Foods,
Journal Year:
2024,
Volume and Issue:
13(24), P. 4150 - 4150
Published: Dec. 21, 2024
This
study
optimized
ultrasound-assisted
enzymatic
(UAE)
extraction
of
TMP
(Tricholoma
matsutake
polysaccharide)
through
response
surface
methodology.
The
optimal
conditions
included
complex
enzyme
comprising
1.15%
cellulase,
0.60%
pectinase,
and
0.95%
dispase,
with
ultrasound
for
24
min
at
84.5
°C
hydrolysis
pH
5.0.
process
yielded
19.74
±
0.51%
TMP,
exceeding
traditional
hot
water
by
over
four
times.
Fourier
transform
infrared
spectroscopy
(FT–IR)
confirmed
that
UAE
did
not
alter
the
structure
TMP.
In
vitro
experiments
indicated
TMP-UAE
demonstrated
enhanced
antioxidant
properties.
Further
purification
DEAE-52
Sephadex
G-100
chromatography
resulted
in
a
homogenous
polysaccharide
fraction
(TMP).
Characterization
has
an
average
molecular
weight
2.79
×
104
Da,
composed
fucose,
galactose,
glucose
mannose
2.00:9.44:86.29:2.28
molar
ratio.
FT–IR
presence
C-O-C
glycosidic
bonds
pyranyl-type
sugar
rings.
Scanning
electron
microscopy
displayed
loose
lamellar
structures
small
pores.
Finally,
exhibited
therapeutic
potential
against
C.
elegans
Parkinson’s
disease,
including
reducing
α-synuclein
aggregation,
protecting
dopaminergic
neurons,
prolonging
lifespan.
provides
efficient
method
insight
into
its
neuroprotective
effect
PD
C.elegans.
Food Science & Nutrition,
Journal Year:
2024,
Volume and Issue:
12(10), P. 8419 - 8431
Published: Sept. 8, 2024
Abstract
Coix
seed
is
recognized
as
a
functional
medicinal
food
due
to
its
valuable
biological
activities,
with
polysaccharides
being
the
primary
active
compounds.
In
this
study,
an
ultrasonic‐assisted
enzymatic
extraction
technique
was
employed,
and
response
surface
methodology
used
optimize
yield
of
9.55
±
0.26%.
A
novel
neutral
polysaccharide,
CSPsN‐1,
purified
molecular
weight
7.75
kDa.
CSPsN‐1
composed
arabinose,
galactose,
glucose,
xylose,
mannose
in
molar
ratios
0.48:
7.92:
86.39:
2.42:
2.79.
Its
backbone
→4)‐α‐D‐Glc
p
‐(1→
→3,4)‐α‐D‐Glc
units,
terminal
residues
α‐D‐Glc
.
vitro
experiments,
enhanced
glucose
consumption
insulin‐resistant
HepG2
cells
upregulated
GLUT4
expression
by
activating
PI3K/AKT
signaling
pathway.
These
findings
suggest
that
holds
significant
promise
ingredient
for
treating
insulin
resistance
related
metabolic
disorders.
