HIV/AIDS and HBV co-infection with optimal control strategies and cost-effectiveness analyses using integer order model
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: Feb. 1, 2025
Hepatitis
B
virus
(HBV)
and
HIV/AIDS
co-infection
is
a
common
infectious
disease
that
has
been
spreading
through
different
nations
in
the
world.
The
main
objective
of
study
to
minimize
number
HBV
HIV
co-infected
individuals
community
cost
incurred
effort
applied
towards
protection
treatment
control
strategies.
In
this
study,
novel
model
formulated
analyzed
investigate
effects
strategies
on
dynamics
community.
qualitative
analyses
we
have
computed
all
models
disease-free
equilibrium
points,
effective
reproduction
numbers
unique
endemic
proved
two
sub-models
points
are
locally
as
well
globally
asymptotically
stable
whenever
their
associated
less
than
one.
our
understanding
no
one
with
optimal
cost-effective
so
problem
carried
out
analysis
by
implementing
Pontryagin's
minimum
principle.
Numerical
simulations
various
combinations
efforts
implemented
then
impacts
treatments
tackle
diseases
Finally,
also
cost-effectiveness
for
From
findings
numerical
observed
proposed
controlling
simultaneously
fundamental
impact
but
strategy
4
(implemented
controls
simultaneously)
most
compared
other
recommend
health
stake
holders
policy
makers
implement
Language: Английский
Non-integer Time Fractional-Order Mathematical Model of the COVID-19 Pandemic Impacts on the Societal and Economic Aspects of Nigeria
International Journal of Applied and Computational Mathematics,
Journal Year:
2024,
Volume and Issue:
10(2)
Published: March 31, 2024
Language: Английский
Modeling and mathematical analysis of fractional order Eye infection (conjunctivitis) virus model with treatment impact: Prelicence and dynamical transmission
Alexandria Engineering Journal,
Journal Year:
2024,
Volume and Issue:
107, P. 33 - 46
Published: July 16, 2024
Language: Английский
A three-dimensional discrete fractional-order HIV-1 model related to cancer cells, dynamical analysis and chaos control
Mathematical Modelling and Numerical Simulation with Applications,
Journal Year:
2024,
Volume and Issue:
4(3), P. 256 - 279
Published: Sept. 30, 2024
In
this
paper,
we
study
a
three-dimensional
discrete-time
model
to
describe
the
behavior
of
cancer
cells
in
presence
healthy
and
HIV-infected
cells.
Based
on
Caputo-like
difference
operator,
construct
fractional-order
biological
system.
This
study's
significance
lies
developing
new
approach
presenting
dynamical
Since
qualitative
analysis
related
existence,
uniqueness,
stability
is
almost
same
as
can
be
found
numerous
existing
papers,
comparing
other
research,
constructing
discrete
system
using
Caputo
operator
particularly
important.
Using
powerful
tools
nonlinear
theory
such
phase
plots,
bifurcation
diagrams,
Lyapunov
exponent
spectrum,
0-1
test,
establish
that
proposed
exhibit
different
states,
including
stable,
periodic,
chaotic
behaviors.
Here,
route
leading
chaos
period-doubling
bifurcation.
Furthermore,
level
quantified
$C_{0}$
complexity
approximate
entropy
algorithms.
The
stabilization
or
suppression
motions
presented,
where
an
efficient
controller
designed
based
systems.
Numerical
simulations
are
provided
validate
theoretical
results
derived
research
paper.
Language: Английский
Fractional-order PID feedback synthesis controller including some external influences on insulin and glucose monitoring
Alexandria Engineering Journal,
Journal Year:
2024,
Volume and Issue:
113, P. 60 - 73
Published: Nov. 16, 2024
Language: Английский
Fractional order mathematical model of Ebola virus under Atangana–Baleanu–Caputo operator
Results in Control and Optimization,
Journal Year:
2023,
Volume and Issue:
13, P. 100332 - 100332
Published: Nov. 7, 2023
The
aim
of
this
paper
is
to
analyze
a
fractional
model
the
Ebola
virus.
This
study
important
because
it
contributes
our
understanding
virus
transmission
dynamics
using
notion
non-local
differential
operators.
We
apply
recently
implemented
Atangana-Baleanu-Caputo
(ABC)
derivative
with
Mittag-Leffler
kernel
closely.
Picard-Lindelof
approach
used
do
comprehensive
existence
and
uniqueness
model's
solutions.
approximate
solutions
order
were
obtained
numerical
technique
ABC
operator,
combination
fundamental
theorem
calculus
two-step
Lagrange
polynomial
interpolation.
innovative
may
offer
new
insights
into
that
not
previously
explored.
Finally,
simulations
illustrate
how
control
parameters
impact
specific
compartments
within
model.
geometrical
representation
gives
significant
information
about
complexity
reliable
simulate
each
compartment
at
various
orders
compare
them
integer-order
simulations,
highlighting
effectiveness
modern
derivatives.
analysis
underscores
enhanced
accuracy
non-integer
derivatives
in
capturing
dynamics.
Language: Английский
Analysis of the fractional SEIR epidemic model with Caputo derivative via resolvents operators and numerical scheme
Discrete and Continuous Dynamical Systems - S,
Journal Year:
2024,
Volume and Issue:
0(0), P. 0 - 0
Published: Jan. 1, 2024
Language: Английский
A fractional derivative model of the dynamic of dengue transmission based on seasonal factors in Thailand
Jiraporn Lamwong,
No information about this author
Puntani Pongsumpun
No information about this author
Journal of Computational and Applied Mathematics,
Journal Year:
2024,
Volume and Issue:
457, P. 116256 - 116256
Published: Sept. 7, 2024
Language: Английский
Kalman filter based on a fractional discrete-time stochastic augmented CoVid-19 model
Journal of Biosafety and Biosecurity,
Journal Year:
2024,
Volume and Issue:
6(2), P. 76 - 98
Published: May 14, 2024
In
this
paper,
we
study
the
dynamics
of
CoVid-19
outbreak
in
Semarang,
Indonesia,
using
a
fractional
model.
We
first
determine
effects
isolation
rate
∊
and
infection
β
on
reproduction
number
R0
infected
V.
find
that
is
directly
proportional
to
inversely
∊.
For
V,
effect
physical
distancing
not
as
significant
changing
As
increases,
V
decreases,
susceptible
individuals
quarantined
decreases
sharply,
recovered
decreases.
Moreover,
vaccination
also
considered.
The
combination
distancing,
isolation,
has
impact
reducing
individuals.
Analysis
dynamical
systems
allows
us
understand
characteristics
our
model,
such
its
boundedness
non-negativity,
existence
equilibrium
points,
uniqueness
solutions,
local
global
stability.
To
validate
introduce
extended
Kalman
filter
(FracEKF)
prediction
method
compare
results
against
reported
data.
FracEKF
modified
version
basic
with
time-fractional
memory
effect.
illustrate
accuracy
model
terms
root
mean
square
error
(RMSE),
normalized
(NRMSE),
absolute
percentage
(MAPE)
for
each
fractional-order.
Varying
reproduces
trends
observed
data
individuals,
i.e.,
when
higher
fractional-order
accuracy.
Furthermore,
values
process
noise
Qf
give
smaller
errors,
whereas
observation
Rf
produce
errors.
α
are
RMSE,NRMSE,
MAPE,
MAPE.
Language: Английский
An epidemiological model for analysing pandemic trends of novel coronavirus transmission with optimal control
Journal of Biological Dynamics,
Journal Year:
2023,
Volume and Issue:
18(1)
Published: Dec. 29, 2023
Symptomatic
and
asymptomatic
individuals
play
a
significant
role
in
the
transmission
dynamics
of
novel
Coronaviruses.
By
considering
dynamical
behaviour
symptomatic
individuals,
this
study
examines
temporal
optimal
control
Coronavirus
disease
propagation
using
an
epidemiological
model.
Biologically
mathematically,
well-posed
epidemic
problem
is
examined,
as
well
threshold
quantity
with
parameter
sensitivity.
Model
parameters
are
quantified
their
relative
impact
on
evaluated.
Additionally,
steady
states
investigated
to
determine
model's
stability
bifurcation.
Using
sensitivity,
we
then
introduce
strategies
for
elimination
disease.
real
data,
numerical
simulations
model
validation
performed
support
theoretical
findings
show
effects
strategies.
Language: Английский