Cited by LEVERAGING 3D PRINTING FOR ADVANCED WOUND DRESSING TECHNOLOGIES BY USING POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS

Review on application of silk fibroin hydrogels in the management of wound healing DOI

Chang Kuk You,

C. Wang,

Zhenjiang Ma

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 298, P. 140082 - 140082

Published: Jan. 18, 2025

Language: Английский

Citations

Innovative technologies for the fabrication of 3D/4D smart hydrogels and its biomedical applications - A comprehensive review DOI

Uday Shashikumar,

Aditya Saraswat,

Kalim Deshmukh

et al.

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 328, P. 103163 - 103163

Published: May 7, 2024

Language: Английский

Citations

Engineered hydrogel platform for diabetic wound healing DOI

Jie Cui, Jianbin Shi, Yanjun Liu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160379 - 160379

Published: Feb. 1, 2025

Language: Английский

Citations

A Multifunctional γ-Polyglutamic Acid Hydrogel for Combined Tumor Photothermal and Chemotherapy DOI

Xiaoqing Jia,

Shige Wang

Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 217 - 217

Published: March 20, 2025

Efficient and precise cancer therapy remains a challenge due to limitations in current treatment modalities. In this study, we developed multifunctional hydrogel system that integrates photothermal (PTT) chemotherapy achieve combined tumor treatment. The hydrogel, composed of γ-polyglutamic acid (γ-PGA), fifth-generation polyamide-amine dendrimers (G5), polydopamine (PDA) nanoparticles, exhibits high conversion efficiency temperature-responsive drug release properties. exhibited 45.6% under 808 nm near-infrared (NIR) irradiation. Drug studies demonstrated cumulative hydrophilic anticancer doxorubicin DOX 79.27% within 72 h mild hyperthermia conditions (50 °C). vivo experiments revealed significant inhibition rate 82.3% with minimal systemic toxicity. Comprehensive vitro evaluations reveal the demonstrates excellent biocompatibility, stability, biodegradability. Unlike conventional systems, our γ-PGA-based uniquely biocompatible biodegradable polymer providing smart responsive platform for therapy. This represents promising combines PTT precision efficacy, robust strategy advanced safer

Language: Английский

Citations

Advances in the development of medical dressings for the treatment of diabetic foot wounds DOI

Ming Cai, Zhao Liu,

Xun Sun

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155575 - 155575

Published: Sept. 7, 2024

Language: Английский

Citations

Utilizing Arthrospira platensis for the fabrication of zinc oxide nanoparticles: Analysis and assessment for enhancing drought tolerance in Sub1A QTL bearing rice seedlings DOI

Abir Das, Suvendra Nath Bagchi, Sayan Pal

et al.

Plant Nano Biology, Journal Year: 2024, Volume and Issue: unknown, P. 100101 - 100101

Published: Oct. 1, 2024

Language: Английский

Citations

Platelet endocytosis and α-granule cargo packaging are essential for normal skin wound healing DOI

Daniëlle M. Coenen, Hammodah R. Alfar, Sidney W. Whiteheart

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

Abstract The high prevalence of chronic wounds, i.e., 2.5-3% the US population, causes a large social and financial burden. Physiological wound healing is multi-step process that involves different cell types growth factors. Platelet-rich plasma or platelet-derived factors have been used to accelerate repair, but their use has controversial with mixed results. Thus, detailed functional understanding platelet functions in beyond hemostasis needed. This study investigated importance α-granule cargo packaging endocytosis dorsal full-thickness excisional skin model using mice defects (Nbeal2 -/- mice) (platelet-specific Arf6 VAMP2/3 Δ mice). We found proper kinetic morphological wounds requires both de novo as well endocytosed cargo. Histological morphometric analyses cross-sectional sections illustrated had delayed (epi)dermal regeneration earlier advanced healing. was reflected by reductions collagen muscle/keratin content, scab formation and/or resolution, re-epithelialization, migration proliferation. Molecular profiling analysis extracts showed impact function extends inflammation, proliferation, tissue remodeling phases via altered expression several bioactive molecules, including IL-1β, VEGF, MMP-9, TIMP-1. These findings provide basis for advances clinical care through better key mechanistic processes cellular interactions (patho)physiological Key points De support physiological Platelet

Language: Английский

Citations

Novel Soft Dosage Forms for Paediatric Applications: Can We 3D-Print Them or Not? DOI

Antoni Białek, Julia Krysztofiak,

Aleksandra Hozakowska

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 187 - 187

Published: March 8, 2025

Over the past years, numerous novel dosage forms, including gels, have been investigated for paediatric treatment due to need provide flexible dose adjustment possibilities, as well a patient-friendly approach drug delivery. Simultaneously, 3D printing technology is continuously advancing and gaining interest tool personalised formulation development. Multiple additive manufacturing methods, semi-solid extrusion, especially used in gel printing, flexibility regarding of active ingredients design soft forms. techniques can be considered possible answer demand medicines tailored small patients’ needs. This review intends present an overview current comparing gel-like non-gel-formulated forms crucial aspects developing those cutting-edge by printing. paper discusses formulations such chewing gums, which still require extensive evaluation, explores question three-dimensional process. Furthermore, it highlights gel-based gummies hydrogels, fabrication has intensively studied previous years. However, research needs advance.

Language: Английский

Citations

Light-Mediated 3D-Printed Wound Dressings Based on Natural Polymers with Improved Adhesion and Antioxidant Properties DOI

Rute Silva,

Matilde Medeiros,

Carlos T.B. Paula

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(8), P. 1114 - 1114

Published: April 20, 2025

The lack of personalized wound dressings tailored to individual needs can significantly hinder healing. Hydrogels offer a promising solution, as they be engineered mimic the extracellular matrix (ECM), providing an optimal environment for repair. integration digital light processing (DLP), high-resolution 3D printing process, allows precise customization hydrogel-based dressings. In this study, gelatin methacrylate (GelMA)-based formulations were prepared in combination with three different polymeric precursors: methacrylated hyaluronic acid (HAMA), poly (ethylene glycol) diacrylate (PEGDA) and allyl cellulose (MCCA). These precursors used print micropatterned patches. printed constructs revealed high gel content good resistance hydrolytic degradation. To improve adhesive antioxidant properties patches, gallic (GA) was incorporated through surface functionalization. This enabled scavenging approximately 80% free radicals within just 4 h. also improved, further enhancement observed upon addition Fe3+ ions. vitro cytocompatibility tests using fibroblast (NHDF) cell line confirmed suitability materials biomedical applications. Thus, study demonstrates potential DLP-printed hydrogels advanced dressing materials.

Language: Английский

Citations

Rapid, organic-solvent-free freeze-thaw fabrication of pure chitosan sponges for scalable potential wound dressing applications DOI

F. Huang, Di Yang, Guohui Bai

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100809 - 100809

Published: April 1, 2025

Language: Английский

Citations