Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations

European journal of medical research, Journal Year: 2025, Volume and Issue: 30(1)

Published: Feb. 4, 2025

Abstract Brain tumor treatment remains a significant challenge due to their high mortality and resistance current therapies. This paper discusses the promising potential of hydrogel-based nanoparticles as innovative drug delivery systems for brain therapy. Extensive characterization techniques reveal ability these Nano-systems demonstrate prolonged blood circulation targeted delivery, leading improved survival rates. Designed with optimized physicochemical characteristics, effectively cross blood–brain barrier, circumventing major impediment brain. By delivering drugs directly bed, enhance therapeutic outcomes minimize adverse effects. In addition, this review investigates characterizing, visualizing, modifying nanoparticles, well standing challenges research avenues clinical application. Further investigations are encouraged by investigate advancements in nanoparticle approaches tumors. includes investigating tailored hydrogels, hybrid systems, computational modeling, integration gene therapy immunotherapy techniques. The study also addresses need enhanced synthesis techniques, stability, scalability, cost-cutting measures overcome obstacles advance use treating Graphical abstract

Language: Английский

A review on exploring the potential of PVA and chitosan in biomedical applications: A focus on tissue engineering, drug delivery and biomedical sensors

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137318 - 137318

Published: Nov. 14, 2024

Language: Английский