An Oxygenated Layer Coating to Enhance the Healing Process of Non-Healing Wounds—A Case Report DOI Creative Commons
Tomasz Miłek, Anna Grzeczkowicz, Agata Lipko

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11200 - 11200

Published: Dec. 1, 2024

The ever-increasing problem of chronic, non-healing wound treatment is a challenge in contemporary medicine. This study aims to verify the effect designed dressing containing coating involving oxygenating factors on promotion healing all phases single clinical case. An alginate-based coating, which incorporates factor, was produced. obtained surface physicochemical features were examined using FTIR and AFM. bandage support modified with developed applied patients who suffered from chronic wounds (treated non-modified commercially available bandages) had required at least 3 months before starting study. During application, chosen characteristics wound-healing process examined. A histological evaluation granulation tissue confirmed presence fibroblasts, hemorrhage, lymphocytes during second week treatment. Moreover, epithelization third exhibited keratinocytes. 100% reduction observed between 4 weeks dressing. It can be recommended that provides supportive through elements, inducing remodeling phase up treatment, for use hard-to-heal

Language: Английский

Antibacterial hydrogel: The sniper of chronic wounds DOI Creative Commons
Shengtai Bian, Huijun Ye, Pan Wang

et al.

BMEMat, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Abstract Chronic wounds are that difficult to heal or do not follow the normal healing process. These include pressure ulcers, diabetic venous and arterial incomplete ulcers. Unlike acute wounds, chronic often even heal. Its pathogenesis involves many factors; bacterial infection is main cause of wound. With increase in population aging, incidence has become a critical issue current medical health field. Management faced with problems long treatment time, difficulty, high cost, repeated attacks disability rate, which seriously threaten patients' ability take care themselves life heavy burden individuals, families society. Over past few years, development antibacterial hydrogels for infections received lot attention. Since only have mechanical properties hydrogels, biocompatibility adjustable functional structure, but also excellent properties, they may be an ideal dressing solve problem wound healing. This article introduces types their characteristics, challenges treating wounds. It classifies antimicrobial based on modes further discusses advancements smart along benefits obstacles using explores directions management.

Language: Английский

Citations

1
Bioresorbable Materials for Wound Management DOI Creative Commons
Hye‐Min Lee, Hanjun Ryu

Biomimetics, Journal Year: 2025, Volume and Issue: 10(2), P. 108 - 108

Published: Feb. 12, 2025

Chronic wounds pose a significant healthcare challenge due to their risk of severe complications, necessitating effective management strategies. Bioresorbable materials have emerged as an innovative solution, offering advantages such eliminating the need for secondary surgical removal, reducing infection risks, and enabling time-delayed drug delivery. This review examines recent advancements in bioresorbable wound healing materials, focusing on systematic systems incorporating electrical stimulation, delivery technologies accelerate tissue repair. The discussion encompasses fundamental principles including resorption mechanisms key properties, alongside preclinical applications that demonstrate practical potential. Critical challenges impeding widespread adoption are addressed, prospects integrating these cutting-edge into clinical practice outlined. Together, insights underscore promise revolutionizing chronic care.

Language: Английский

Citations

0
A Multifunctional Hydrogel for Infected Chronic Wounds Management: Integrated pH Sensing, Photothermal Therapy, and Ion Release DOI
Ziqi Zhou, Liyan Zhang, Muyan Qin

et al.

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

ABSTRACT Chronic wound healing is often compromised by bacterial infection, and pH changes strongly correlate with infection. Therefore, the development of dressings capable real‐time monitoring, antimicrobial activity, tissue repair crucial for effective management infected chronic wounds. This study reports a novel multifunctional composite hydrogel (GM‐C‐mBG@P) synthesized incorporating microwave‐synthesized carbon quantum dots (CQDs) polydopamine‐modified mesoporous bioactive glass nanoparticles (mBG@P) into modified gelatin methacryloyl (GelMA). The incorporated polydopamine (PDA) confers excellent photothermal properties to hydrogel, enabling activity. Under 360 nm UV excitation, fluorescence intensity CQDs in GM‐C‐mBG@P exhibits strong linear correlation pH, monitoring. Furthermore, mBG@P can gradually dissolve calcium, silicon, boron, other functional ions enhance bioactivity functionality accelerate healing. These findings suggest that has potential serve as promising dressing treatment

Language: Английский

Citations

0
Bio-inspired bacterial cellulose-based hydrogel films for controlled ciprofloxacin release DOI Creative Commons
Florina Lucica Zorilă, Gabriela Toader,

Mioara Alexandru

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100796 - 100796

Published: April 1, 2025

Language: Английский

Citations

0
Evaluating the Antibacterial Properties of a Zeolite-Chitosan Biocomposite for Medical Applications DOI Creative Commons

Saeideh Hematian,

Kiana Peyvandi, Mehdi Dadashpour

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 1(4)

Published: Nov. 26, 2024

: Antibacterial substances have garnered significant interest in recent years due to their applications medical equipment, prostheses, and drug delivery systems. Consequently, it is essential identify develop biomaterials with antibacterial properties tailored specific target sites. This study utilizes two natural biomaterials: Chitosan zeolite. Zeolite, a bioceramic an aluminosilicate structure, exhibits high mechanical resistance, making ideal for use areas of the body that endure pressure, such as bones teeth. Chitosan, on other hand, possesses excellent application various bodily tissues. However, polymers like chitosan are often combined materials composites enhance resistance. research investigates biocomposite made from zeolite against types bacteria: Staphylococcus aureus (gram-positive) Escherichia coli (gram-negative). The results revealed composite exhibited strong resistance E. but comparatively lower S. aureus. Furthermore, findings suggest plays more role conferring these properties.

Language: Английский

Citations

0
An Oxygenated Layer Coating to Enhance the Healing Process of Non-Healing Wounds—A Case Report DOI Creative Commons
Tomasz Miłek, Anna Grzeczkowicz, Agata Lipko

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11200 - 11200

Published: Dec. 1, 2024

The ever-increasing problem of chronic, non-healing wound treatment is a challenge in contemporary medicine. This study aims to verify the effect designed dressing containing coating involving oxygenating factors on promotion healing all phases single clinical case. An alginate-based coating, which incorporates factor, was produced. obtained surface physicochemical features were examined using FTIR and AFM. bandage support modified with developed applied patients who suffered from chronic wounds (treated non-modified commercially available bandages) had required at least 3 months before starting study. During application, chosen characteristics wound-healing process examined. A histological evaluation granulation tissue confirmed presence fibroblasts, hemorrhage, lymphocytes during second week treatment. Moreover, epithelization third exhibited keratinocytes. 100% reduction observed between 4 weeks dressing. It can be recommended that provides supportive through elements, inducing remodeling phase up treatment, for use hard-to-heal

Language: Английский

Citations

0