The Potential of Hydrogel Preparations Containing Plant Materials in Supporting the Treatment of Vaginal and Vulvar Infections—Current State of Knowledge

Polymers, Journal Year: 2025, Volume and Issue: 17(4), P. 470 - 470

Published: Feb. 11, 2025

Vaginal hydrogels are a modern alternative to solid (tablets, globules) and other semi-solid forms of medication (ointments, creams) in the control pathogenic microorganisms diseases female reproductive tract. This review aims summarize current state knowledge regarding efficacy containing plant materials treatment vaginal vulvar infections. New therapies essential address growing antimicrobial resistance crisis. Google Scholar, Web Science, Cochrane, Medline (PubMed) databases were searched. Twenty-five studies included review, including basic, pre-clinical, clinical studies. The results obtained confirmed therapeutic potential raw embedded polymer matrix hydrogels. However, due small number trials conducted, further research this area is needed.

Language: Английский

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Editorial: Bioactive containing plant based waste for (nano)-biocomposites: applications in biomedicine, health, and bioremediation

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 28, 2025

In this order of ideas, Bariş & Kötekoğlu (2024) have developed an organogelator, which is a molecule that, when dissolving in organic solvent, forms gel. It can be used small quantities and applications cosmetics, optics, other fields (Zeng et al., 2021). The compound research was 1(N1,N2-bis(2S,3S)-1-((4-(tert-butyl)benzyl)amino)-3-methyl-1-oxopentan-2yl)oxalamide), are biocompatible with high penetration capacity, useful as transporters topical bioactive molecules great stability. Also, to determine the capacity capture gels obtained, non-steroidal anti-inflammatories (NSAIDS) ibuprofen naproxen were used, safer for muscle pains application, due gastric intolerance that both drugs produce (Manoukian 2017). Ultimately, demonstrates novel organogel carrier system medicines medical use. Thus, organogels oleogels promising formulations delivery compounds from waste agriculture food industry (Souza Pereira 2023).In addition, Ullah anticarcinogenic (Mottaghi Abbaszadeh This functionalized 62 nanostructure synthetized using fruit Celtis tournefortii (endemic tree southwestern 63 slopes Etna Nebrodi mountains) obtain composite activated carbon named CtAC. 64Later CtAC employed synthesis IONPs@CtAC magnetic nanocomposite loaded 65 morin; it evaluated cytotoxicity against HT-29 (colorectal), T98-G (glioblastoma) cancer 66 cell lines, human umbilical vein endothelial (HUVEC) healthy line.

Language: Английский

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Eco-Friendly Conductive Hydrogels: Towards Green Wearable Electronics

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 220 - 220

Published: March 21, 2025

The rapid advancement of wearable electronics has catalyzed the development flexible, lightweight, and highly conductive materials. Among these, hydrogels have emerged as promising candidates due to their tissue-like properties, which can minimize mechanical mismatch between flexible devices biological tissues excellent electrical conductivity, stretchability biocompatibility. However, environmental impact synthetic components production processes in conventional poses significant challenges sustainable application. This review explores recent advances eco-friendly used healthcare, focusing on design, fabrication, applications green electronics. Emphasis is placed use natural polymers, bio-based crosslinkers, synthesis methods improve sustainability while maintaining high performance. We discuss incorporation polymers carbon-based nanomaterials into environmentally benign matrices. Additionally, article highlights strategies for improving biodegradability, recyclability, energy efficiency these By addressing current limitations future opportunities, this aims provide a comprehensive understanding friendly basis next generation technologies.

Language: Английский

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Applications of Hydrogels in Emergency Therapy

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 234 - 234

Published: March 23, 2025

Interest in developing new, effective materials for emergency hemostasis and wound healing is steadily increasing, particularly use emergency, surgical, military situations. Hydrogels, with their unique retention, swelling, biocompatibility properties, have emerged as essential therapy. This review provides a comprehensive examination of recent hydrogel applications acute medical scenarios, including hemostasis, management, drug delivery, soft tissue replacement, engineering. We discuss the physicochemical properties that make hydrogels suitable rapid response situations, such tunable mechanical strength, adhesiveness, responsiveness to environmental stimuli, ability encapsulate release therapeutic agents. Additionally, article explores advancements smart self-healing antimicrobial providing insights into potential revolutionize care increase survival rates both civilian applications. Through critical evaluation current clinical trials practical deployments, this highlights successes challenges faced integrating protocols, roadmap future research development dynamic field.

Language: Английский

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Synthesis and Characterization of a Superabsorbent Polymer Gel Using a Simultaneous Irradiation Technique on Corn Straw

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 244 - 244

Published: March 26, 2025

Utilizing gamma rays as an initiating agent, a simultaneous irradiation method was applied to graft acrylic acid and acrylamide onto corn straw that had been decrystallized using NaOH/urea solution at reduced temperature, aiming fabricate superabsorbent polymer gel (SAPG) capable of absorbing significantly more water. The structural attributes the straw, SAPG were analyzed via Fourier transform infrared spectroscopy (FTIR), X-ray crystal powder diffraction (XRD), thermogravimetric analysis (TG), scanning electron microscopy (SEM). To enhance SAPG’s performance, optimization various parameters carried out, such dose, dose rate, ratio monomer proportion (AA) (Am), degree neutralization. resulting exhibited distilled water absorption 1033 g/g 90 in 0.9 wt.% NaCl solution, with radiation 5 kGy, rate 1.5 kGy/h, AA-to-AM mass 1.2, monomer-to-CS 7, 90% AA

Language: Английский

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Geranium essential oil downregulates virulence genes and mitigates MRSA wound infections through a multifunctional hydrogel

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 310, P. 143197 - 143197

Published: April 17, 2025

Language: Английский

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Multifunctional hydrogel of zein-tartaric acid encapsulated with oregano essential oils to combat Pseudomonas aeruginosa through biofilm inhibition

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106934 - 106934

Published: April 1, 2025

Language: Английский

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Role of advanced cleaning and sanitation techniques in biofilm prevention on dairy equipment

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2025, Volume and Issue: 24(3)

Published: April 22, 2025

Abstract Biofilm formation on dairy equipment is a persistent challenge in the industry, contributing to product contamination, inefficiency, and economic losses. Traditional methods such as manual cleaning basic chemical sanitation are discussed foundational approaches, followed by an in‐depth investigation of cutting‐edge technologies, including clean‐in‐place systems, high‐pressure cleaning, foam ultrasonic electrochemical dry ice blasting, robotics, nanotechnology‐based agents, enzymatic cleaners, oxidizing agents. Enhanced techniques, steam, pulsed light, acidic alkaline electrolyzed water, hydrogen peroxide vapor, microbubble technology, biodegradable biocides, highlighted for their potential achieve superior while promoting sustainability. The effectiveness, feasibility, limitations these evaluated, emphasizing role maintaining hygiene reducing biofilm‐associated risks. Additionally, challenges, compatibility, cost, regulatory compliance, addressed, along with insights into future directions innovations, automation, smart green solutions. This review provides comprehensive resource researchers, industry professionals, policymakers aiming tackle biofilm production systems enhance food safety, operational efficiency,

Language: Английский

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Hydrogel for Sustained Delivery of Therapeutic Agents

Gels, Journal Year: 2024, Volume and Issue: 10(11), P. 717 - 717

Published: Nov. 7, 2024

In recent years, hydrogels have emerged as a highly promising platform for the sustained delivery of therapeutic agents, addressing critical challenges in drug systems, from controlled release to biocompatibility [...].

Language: Английский

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Enhancement of Water Uptake in Composite Superabsorbents Based on Carboxymethyl Cellulose Through Porogen Incorporation and Lyophilization

Gels, Journal Year: 2024, Volume and Issue: 10(12), P. 797 - 797

Published: Dec. 5, 2024

Carboxymethyl cellulose sodium salt (CMC)-based superabsorbents are promising materials for the development of agricultural matrices aimed at water management and slow-release fertilizer production. However, an increase in CMC content tends to reduce their water-absorbing capacity. This study aims develop a cost-effective method producing eco-friendly with enhanced capacity by incorporating porogen employing lyophilization. Superabsorbents containing 10 wt% (CMC-SAPs) were synthesized via free radical polymerization addition 0, 5, or ammonium carbonate as porogen, followed The CMC-SAPs characterized using Fourier-transform infrared spectroscopy, scanning electron microscopy, thermogravimetric analysis, differential calorimetry, X-ray diffraction. results revealed that prepared incorporation and/or subjected lyophilization exhibited well-developed surfaces featuring macropores cavities. Incorporating 5 lyophilization, increased equilibrium swelling ratio 61%. improvement was attributed surface morphology modified CMC-SAPs, which facilitated molecule diffusion into SAP matrix, confirmed open porosity measurements. hypothesis further supported coefficient values, higher porogen-containing lyophilized SAPs compared unmodified samples. Moreover, demonstrated good reusability. Thus, combination subsequent represents approach enhancing uptake CMC-based composite sustainable applications.

Language: Английский

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