Injectable Biopolymer-Based Hydrogels: A Next-Generation Platform for Minimally Invasive Therapeutics DOI Creative Commons
Nargish Parvin, Sang Woo Joo, Tapas Kumar Mandal

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(6), P. 383 - 383

Published: May 23, 2025

Injectable biopolymer-based hydrogels have emerged as a powerful class of biomaterials designed for minimally invasive therapeutic strategies in modern medicine. These smart hydrogels, derived from natural biopolymers, such alginate, chitosan, gelatin, hyaluronic acid, and collagen, offer unique advantages, including biocompatibility, biodegradability, the ability to mimic extracellular matrix. This review provides comprehensive overview recent advancements design, crosslinking mechanisms, biofunctionality injectable tailored targeted drug delivery tissue regeneration. Special attention is given their role situ gelling systems, cancer therapy, musculoskeletal repair, neural Challenges related mechanical strength, degradation control, clinical translation are also discussed, along with future perspectives scalable manufacturing regulatory approval.

Language: Английский

Injectable Biopolymer-Based Hydrogels: A Next-Generation Platform for Minimally Invasive Therapeutics DOI Creative Commons
Nargish Parvin, Sang Woo Joo, Tapas Kumar Mandal

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(6), P. 383 - 383

Published: May 23, 2025

Injectable biopolymer-based hydrogels have emerged as a powerful class of biomaterials designed for minimally invasive therapeutic strategies in modern medicine. These smart hydrogels, derived from natural biopolymers, such alginate, chitosan, gelatin, hyaluronic acid, and collagen, offer unique advantages, including biocompatibility, biodegradability, the ability to mimic extracellular matrix. This review provides comprehensive overview recent advancements design, crosslinking mechanisms, biofunctionality injectable tailored targeted drug delivery tissue regeneration. Special attention is given their role situ gelling systems, cancer therapy, musculoskeletal repair, neural Challenges related mechanical strength, degradation control, clinical translation are also discussed, along with future perspectives scalable manufacturing regulatory approval.

Language: Английский

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