Gels,
Journal Year:
2025,
Volume and Issue:
11(3), P. 165 - 165
Published: Feb. 26, 2025
Hypericum
perforatum
L.
(H.P.)
is
a
species
with
well-documented
history
of
use
in
wound
healing
practices
across
the
globe.
The
objective
this
study
was
twofold:
firstly,
to
evaluate
vivo
efficacy
liposomal
situ
gel
formulations
healing,
both
clinically
and
histopathologically,
secondly,
determine
physicochemical
characterization
formulations.
vitro
studies
will
be
assessed
terms
particle
size,
zeta
potential,
release
kinetics,
rheological
behaviors,
antioxidant
antimicrobial
properties.
evaluated
clinical
animal
experiments
pathology
studies.
in-situ
hydrogel
were
prepared
using
physical
cross-linking
method
Poloxamer
188,
407,
Ultrez
21,
30.
liposome
phospholipid
90H
lipoid
S100
thin
film
solvent
evaporation
method.
activity
samples
through
employing
DPPH
activity,
ABTS+
test,
FRAP
test.
determination
MIC
MBC
values
96-well
plate
In
vivo,
36
male
New
Zealand
rabbits
aged
32–36
weeks
utilized,
six
each
group.
groups
composed
distinct
groups,
including
conventional
HHPM,
three
different
commercial
preparations,
control
group
(n
=
6).
HHPM-LG8
formulation
developed
found
applicable
all
its
new
demonstrated
notable
result
that
supported
by
itself.
Canadian Metallurgical Quarterly,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 20
Published: Jan. 9, 2025
Carbon
Capture
Utilisation
and
Storage
(CCUS)
technologies
have
become
increasingly
important
to
mitigate
greenhouse
gas
emissions
combat
climate
change.
One
promising
avenue
of
CCUS
is
the
use
industrial
waste
streams
as
feedstock
for
CO2
sequestration.
Iron
steel
slag,
by-products
manufacturing,
shown
potential
effective
adsorbents.
This
current
work
thus
provides
a
comprehensive
review
production
chemical
composition
iron
slags
its
in
sequestration,
synthesis
nanocomposite
hydrogels
via
sol–gel
method,
applications
emerging
trends
The
process
viable
technique
hydrogels,
offering
high
surface
area,
tunable
porosity,
enhanced
reactivity
suitable
CO₂
highlighted
calcium
oxide
content
reactive
sites
slags,
facilitating
sequestration
through
carbonation.
Challenges
such
limited
adsorption
capacity
structural
degradation
over
time
will
be
addressed
by
incorporating
slag
into
hydrogel
matrices.
findings
further
suggest
that
can
improve
functionality,
adding
mechanical
resilience
promoting
fixation
molecules.
study
concluded
slag-based
offer
promising,
sustainable
solution
with
future
research
needed
optimise
these
materials
scalable
environmental
remediation.
Macromolecular Bioscience,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 21, 2025
Abstract
Regenerating
skin
tissue
remains
a
major
challenge
in
medical
science,
especially
due
to
the
risk
of
scarring
and
prolonged
healing,
which
becomes
even
more
complicated
people
with
diabetes.
Recent
advancements
have
led
creation
therapeutic
dressings
incorporating
drug‐delivery
systems
tackle
these
issues.
Exosomes
(Exos)
derived
from
mesenchymal
stem
cells
(MSCs)
gained
significant
attention
for
mediating
therapy
without
directly
using
cells,
thanks
their
natural
anti‐inflammatory
repair
properties
mirroring
those
MSCs.
In
this
study,
an
advanced
wound
dressing
combines
chitosan
(CS)
polyethylene
glycol
(PEG)
hydrogel
adipose
MSCs‐derived
Exos
(ADMSCs‐Exos).
This
composite,
formed
straightforward
blending
technique,
is
engineered
improve
healing
process
severe
injuries
by
steadily
releasing
as
degrades.
The
vitro
studies
demonstrate
that
hydrogel‐exosome
greatly
enhances
endothelial
cell
migration,
reduces
oxidative
stress,
promotes
angiogenesis,
crucial
effective
healing.
Additionally,
real
time‐polymerase
chain
reaction
(RT‐PCR)
analysis
revealed
upregulation
key
genes
involved
processes,
supporting
potential
hydrogel‐Exo
combination.
These
findings
emphasize
hydrogel‐Exos
combination
innovative
promising
solution
care.
Gels,
Journal Year:
2025,
Volume and Issue:
11(3), P. 165 - 165
Published: Feb. 26, 2025
Hypericum
perforatum
L.
(H.P.)
is
a
species
with
well-documented
history
of
use
in
wound
healing
practices
across
the
globe.
The
objective
this
study
was
twofold:
firstly,
to
evaluate
vivo
efficacy
liposomal
situ
gel
formulations
healing,
both
clinically
and
histopathologically,
secondly,
determine
physicochemical
characterization
formulations.
vitro
studies
will
be
assessed
terms
particle
size,
zeta
potential,
release
kinetics,
rheological
behaviors,
antioxidant
antimicrobial
properties.
evaluated
clinical
animal
experiments
pathology
studies.
in-situ
hydrogel
were
prepared
using
physical
cross-linking
method
Poloxamer
188,
407,
Ultrez
21,
30.
liposome
phospholipid
90H
lipoid
S100
thin
film
solvent
evaporation
method.
activity
samples
through
employing
DPPH
activity,
ABTS+
test,
FRAP
test.
determination
MIC
MBC
values
96-well
plate
In
vivo,
36
male
New
Zealand
rabbits
aged
32–36
weeks
utilized,
six
each
group.
groups
composed
distinct
groups,
including
conventional
HHPM,
three
different
commercial
preparations,
control
group
(n
=
6).
HHPM-LG8
formulation
developed
found
applicable
all
its
new
demonstrated
notable
result
that
supported
by
itself.
