Advanced NanoBiomed Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 23, 2024
The
slow
healing
process
of
diabetic
wound
due
to
persisting
infections
in
bed,
owing
hyperglycemia,
makes
the
search
for
efficient
treatments
pending.
While
it
is
complicated
increase
closure
rate
diabetic‐related
wounds
complex
pathology,
treatment
such
with
hydrogels
seen
as
a
promising
approach
and
pursued
over
years.
However,
where
this
research
currently
standing
terms
clinical
translation
these
different
multifunctional
stimuli‐responsive
hydrogel
bandages
accelerate
foot
ulcer
help
improve
life
patients
future
management?
This
perspective
article
will
review
some
most
important
advancements
field
conclude
perspectives,
considered
relevant
context.
Journal of Biomaterials Science Polymer Edition,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 15
Published: April 25, 2025
Diabetes,
both
Type
1
and
2,
often
leads
to
chronic
wounds
due
impaired
healing
processes,
marked
by
prolonged
inflammation,
delayed
blood
vessel
formation,
abnormal
collagen
production.
These
issues
disrupt
normal
tissue
regeneration,
slowing
healing.
To
address
these
challenges,
polymer-based
wound
dressings
are
being
explored
as
a
promising
solution.
Natural
polymers
like
alginate,
chitosan,
hyaluronic
acid,
well
synthetic
ones
PCL,
PLA,
PLGA,
offer
potential
for
more
effective
materials
can
be
used
in
advanced
delivery
systems,
such
nanofibrous
scaffolds,
nanoparticles,
hydrogels,
which
help
deliver
medications,
maintain
moist
environment,
stimulate
cell
growth.
By
improving
the
systems
provide
new
hope
diabetic
patients
with
slow-to-heal
wounds,
enhancing
therapeutic
outcomes
accelerating
innovations
could
significantly
improve
management
of
diabetes.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(30)
Published: Aug. 17, 2024
Abstract
Nucleic
acid
drugs
are
one
of
the
hot
spots
in
field
biomedicine
recent
years,
and
play
a
crucial
role
treatment
many
diseases.
However,
its
low
stability
difficulty
target
drug
delivery
bottlenecks
restricting
application.
Hydrogels
proven
to
be
promising
for
improving
nucleic
drugs,
reducing
adverse
effects
rapid
degradation,
sudden
release,
unnecessary
diffusion
drugs.
In
this
review,
strategies
loading
hydrogels
summarized
various
biomedical
research,
classify
mechanism
principles
these
strategies,
including
electrostatic
binding,
hydrogen
bond
based
hydrophobic
covalent
binding
indirect
using
carriers.
addition,
review
also
describes
release
photostimulation‐based
enzyme‐responsive
pH‐responsive
temperature‐responsive
release.
Finally,
applications
future
research
directions
delivering
medicine
discussed.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 12999 - 13027
Published: Dec. 1, 2024
Diabetic
foot
ulcers
present
a
formidable
challenge
due
to
colonization
by
biofilm-forming
microorganisms,
heightened
oxidative
stress,
and
continuous
wound
maceration
caused
excessive
exudation.
Advanced NanoBiomed Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 23, 2024
The
slow
healing
process
of
diabetic
wound
due
to
persisting
infections
in
bed,
owing
hyperglycemia,
makes
the
search
for
efficient
treatments
pending.
While
it
is
complicated
increase
closure
rate
diabetic‐related
wounds
complex
pathology,
treatment
such
with
hydrogels
seen
as
a
promising
approach
and
pursued
over
years.
However,
where
this
research
currently
standing
terms
clinical
translation
these
different
multifunctional
stimuli‐responsive
hydrogel
bandages
accelerate
foot
ulcer
help
improve
life
patients
future
management?
This
perspective
article
will
review
some
most
important
advancements
field
conclude
perspectives,
considered
relevant
context.
