Genes,
Journal Year:
2024,
Volume and Issue:
15(6), P. 690 - 690
Published: May 26, 2024
Genomic
prediction
plays
an
increasingly
important
role
in
modern
animal
breeding,
with
predictive
accuracy
being
a
crucial
aspect.
The
classical
linear
mixed
model
is
gradually
unable
to
accommodate
the
growing
number
of
target
traits
and
intricate
genetic
regulatory
patterns.
Hence,
novel
approaches
are
necessary
for
future
genomic
prediction.
In
this
study,
we
used
illumina
50K
SNP
chip
genotype
4190
egg-type
female
Rhode
Island
Red
chickens.
Machine
learning
(ML)
bioinformatics
methods
were
integrated
fit
genotypes
10
economic
We
evaluated
effectiveness
ML
using
Pearson
correlation
coefficients
RMSE
between
predicted
actual
phenotypic
values
compared
them
rrBLUP
BayesA.
Our
results
indicated
that
algorithms
exhibit
significantly
superior
performance
BayesA
predicting
body
weight
eggshell
strength
traits.
Conversely,
demonstrated
2–58%
higher
egg
numbers.
Additionally,
incorporation
suggestively
significant
SNPs
obtained
through
GWAS
into
models
resulted
increase
0.1–27%
across
nearly
all
These
findings
suggest
potential
combining
techniques
improve
future.
Healthcare,
Journal Year:
2023,
Volume and Issue:
11(20), P. 2760 - 2760
Published: Oct. 18, 2023
In
recent
years,
there
has
been
the
notable
emergency
of
artificial
intelligence
(AI)
as
a
transformative
force
in
multiple
domains,
including
orthodontics.
This
review
aims
to
provide
comprehensive
overview
present
state
AI
applications
orthodontics,
which
can
be
categorized
into
following
domains:
(1)
diagnosis,
cephalometric
analysis,
dental
facial
skeletal-maturation-stage
determination
and
upper-airway
obstruction
assessment;
(2)
treatment
planning,
decision
making
for
extractions
orthognathic
surgery,
outcome
prediction;
(3)
clinical
practice,
practice
guidance,
remote
care,
documentation.
We
have
witnessed
broadening
application
accompanied
by
advancements
its
performance.
Additionally,
this
outlines
existing
limitations
within
field
offers
future
perspectives.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 10, 2024
Deep
learning
has
emerged
as
a
revolutionary
technical
advancement
in
modern
orthodontics,
offering
novel
methods
for
diagnosis,
treatment
planning,
and
outcome
prediction.
Over
the
past
25
years,
field
of
dentistry
widely
adopted
information
technology
(IT),
resulting
several
benefits,
including
decreased
expenses,
increased
efficiency,
need
human
expertise,
reduced
errors.
The
transition
from
preset
rules
to
real-world
examples,
particularly
machine
(ML)
artificial
intelligence
(AI),
greatly
benefited
organization,
analysis,
storage
medical
data.
learning,
type
AI,
enables
robots
mimic
neural
networks,
allowing
them
learn
make
decisions
independently
without
explicit
programming.
Its
ability
automate
cephalometric
analysis
enhance
diagnosis
through
3D
imaging
revolutionized
orthodontic
operations.
models
have
potential
significantly
improve
outcomes
reduce
errors
by
accurately
identifying
anatomical
characteristics
on
radiographs,
thereby
expediting
analytical
processes.
Additionally,
use
technologies
such
cone-beam
computed
tomography
(CBCT)
can
facilitate
precise
comprehensive
examinations
craniofacial
architecture,
tooth
movements,
airway
dimensions.
In
today's
era
personalized
medicine,
deep
learning's
customize
treatments
individual
patients
propelled
orthodontics
forward
tremendously.
However,
it
is
essential
address
issues
related
data
privacy,
model
interpretability,
ethical
considerations
before
practices
an
responsible
manner.
Modern
evolving,
thanks
deliver
more
accurate,
effective,
treatments,
improving
patient
care
develops.
Animals,
Journal Year:
2025,
Volume and Issue:
15(4), P. 525 - 525
Published: Feb. 12, 2025
The
increasing
volume
of
genome
sequencing
data
presents
challenges
for
traditional
genome-wide
prediction
methods
in
handling
large
datasets.
Machine
learning
(ML)
techniques,
which
can
process
high-dimensional
data,
offer
promising
solutions.
This
study
aimed
to
find
a
method
local
pig
breeds,
using
10
datasets
with
varying
SNP
densities
derived
from
imputed
515
Rongchang
pigs
and
the
Pig
QTL
database.
Three
reproduction
traits—litter
weight,
total
number
piglets
born,
born
alive—were
predicted
six
five
ML
methods,
including
kernel
ridge
regression,
random
forest,
Gradient
Boosting
Decision
Tree
(GBDT),
Light
Machine,
Adaboost.
methods’
efficacy
was
evaluated
fivefold
cross-validation
independent
tests.
predictive
performance
both
initially
increased
density,
peaking
at
800–900
k
SNPs.
outperformed
ones,
showing
improvements
0.4–4.1%.
integration
GWAS
database
enhanced
robustness.
models
exhibited
superior
generalizability,
high
correlation
coefficients
(0.935–0.998)
between
test
results.
GBDT
forest
showed
computational
efficiency,
making
them
genomic
livestock
breeding.
Animal Research and One Health,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 1, 2024
Abstract
Spotted
sea
bass
(
Lateolabrax
maculatus
)
is
a
species
of
significant
economic
importance
in
aquaculture.
However,
genetic
degeneration,
such
as
declining
growth
performance,
has
severely
impeded
industry
development,
necessitating
urgent
improvement.
Here,
we
conducted
genome‐wide
association
study
(GWAS)
and
genomic
prediction
for
traits
using
insertion
deletion
(InDel)
markers,
systematically
compared
the
results
with
our
previous
studies
single
nucleotide
polymorphism
(SNP)
markers.
A
total
97
InDels
including
6
bp
an
exon
region
were
identified.
It
worth
noting
that
only
5
1
candidate
genes
DY
TS
populations
also
detected
GWAS
SNPs,
numerous
novel
c4b
,
fgf4
dnajb9
identified
vital
genes.
Moreover,
several
growth‐related
procedures,
development
bone
muscle,
detected.
These
findings
indicated
InDel‐based
can
provide
valuable
complement
to
SNP‐based
studies.
The
comparison
predictive
performance
length
trait
under
different
marker
selection
strategies
models
strategy
exhibits
more
stable
evenly
strategy.
Additionally,
support
vector
machine
model
demonstrated
better
accuracy
efficiency
than
traditional
best
linear
unbiased
Bayes
models.
Furthermore,
superior
InDel
markers
SNP
highlighted
potential
enhance
efficiency.
Our
carry
implications
dissecting
mechanisms
contributing
improvement
spotted
through
resources.