Mitochondrial Diversity and Phylogenetic Relationship of Eight Native Bulgarian Sheep Breeds DOI Creative Commons
Georgi Kalaydzhiev,

Nadezhda Palova,

Heliana Dundarova

et al.

Animals, Journal Year: 2023, Volume and Issue: 13(23), P. 3655 - 3655

Published: Nov. 25, 2023

The geographical, geomorphological, and climatic characteristics of Bulgaria are particularly favorable for animal breeding and, above all, pastoral farming sheep breeding. These conditions created prerequisites the creation about 30 unique local breeds sheep. In this study we investigated genetic diversity eight most popular Bulgarian native breeds, based on sequence analysis a part mitochondrial D-loop region. An almost entire DNA (mtDNA) region (1180 bp) was amplified sequenced. obtained results showed presence large number haplotypes-225, belonging to two main haplogroups. majority samples high prevalence European haplogroup B (95.2%) while remaining individuals were assigned A (4.8%). None other reported haplogroups observed. polymorphic sites, nucleotide haplotype (240, 0.01237, 0.9968, respectively), which is evidence multiple maternal origins in all populations. Tajima D-test value populations -1.905 (p < 0.05), indicating that abundance rare alleles likely due population expansion after recent bottleneck. Median joining network haplotypes formed star-like network, revealed weak differentiation gene flow between breeds.

Language: Английский

Integrative genetic and epigenetic control of skeletal muscle fiber traits in agricultural animals DOI Creative Commons
Xiaolong Chang, Junwu Ma

Frontiers in Genetics, Journal Year: 2025, Volume and Issue: 16

Published: May 2, 2025

Skeletal muscle fiber traits are fundamental to meat production and the quality of agricultural animals. The rich genetic resources diverse phenotypic expression in animal species provide invaluable materials for investigating molecular regulatory mechanisms underlying myofiber development characteristics, optimizing breeding strategies, developing models human muscle-related diseases. This review presents an integrative perspective on epigenetic regulation skeletal development, incorporating evolutionary, genomic, epigenomic, multi-omics insights. We focus architecture causative or candidate genes traits, as revealed by genome-wide association studies (GWAS) selective sweep signatures, underscoring their adaptive significance potential breeding. role mechanisms, such DNA methylation, histone modifications, non-coding RNAs, linking variation is also discussed. By synthesizing multi-omic data, we a comprehensive understanding networks driving growth differentiation. aims consolidate current knowledge offer actionable insights advance research, applications biomedical fields.

Language: Английский

Citations

0
Population structure and selective signature of Kirghiz sheep by Illumina Ovine SNP50 BeadChip DOI Creative Commons
Ruizhi Yang,

Zhipeng Han,

Wen Zhou

et al.

PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e17980 - e17980

Published: Sept. 19, 2024

By assessing the genetic diversity and associated selective traits of Kirghiz sheep (KIR), we aim to uncover mechanisms that contribute sheep's adaptability Pamir Plateau environment.

Language: Английский

Citations

1
Mitochondrial Diversity and Phylogenetic Relationship of Eight Native Bulgarian Sheep Breeds DOI Creative Commons
Georgi Kalaydzhiev,

Nadezhda Palova,

Heliana Dundarova

et al.

Animals, Journal Year: 2023, Volume and Issue: 13(23), P. 3655 - 3655

Published: Nov. 25, 2023

The geographical, geomorphological, and climatic characteristics of Bulgaria are particularly favorable for animal breeding and, above all, pastoral farming sheep breeding. These conditions created prerequisites the creation about 30 unique local breeds sheep. In this study we investigated genetic diversity eight most popular Bulgarian native breeds, based on sequence analysis a part mitochondrial D-loop region. An almost entire DNA (mtDNA) region (1180 bp) was amplified sequenced. obtained results showed presence large number haplotypes-225, belonging to two main haplogroups. majority samples high prevalence European haplogroup B (95.2%) while remaining individuals were assigned A (4.8%). None other reported haplogroups observed. polymorphic sites, nucleotide haplotype (240, 0.01237, 0.9968, respectively), which is evidence multiple maternal origins in all populations. Tajima D-test value populations -1.905 (p < 0.05), indicating that abundance rare alleles likely due population expansion after recent bottleneck. Median joining network haplotypes formed star-like network, revealed weak differentiation gene flow between breeds.

Language: Английский

Citations

1