Microbiota and Autism: A Review on Oral and Gut Microbiome Analysis Through 16S rRNA Sequencing DOI Creative Commons

Federico Anaclerio,

M. Minelli,

Ivana Antonucci

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2686 - 2686

Published: Nov. 25, 2024

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with multifactorial etiologies, including genetic, environmental, and microbiological factors. In recent years, increasing attention has been given to the role of gut microbiota in ASD. Emerging evidence suggests that dysbiosis may influence central nervous system through gut-brain axis, potentially impacting behavior neurodevelopment. The use 16S rRNA gene sequencing become pivotal tool profiling microbial communities associated ASD, offering valuable insights into bacterial diversity, composition, potential functional roles. This review aims provide comprehensive analysis current findings on relationship between oral particular focus studies utilizing sequencing. We will explore how microbiome alterations contribute ASD pathophysiology, discuss limitations existing research, propose future directions for integration diagnostics treatment strategies. These underscore modulating symptoms. data suggest specific taxa are consistently altered which have implications understanding axis its

Language: Английский

Microbiota and Autism: A Review on Oral and Gut Microbiome Analysis Through 16S rRNA Sequencing DOI Creative Commons

Federico Anaclerio,

M. Minelli,

Ivana Antonucci

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2686 - 2686

Published: Nov. 25, 2024

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with multifactorial etiologies, including genetic, environmental, and microbiological factors. In recent years, increasing attention has been given to the role of gut microbiota in ASD. Emerging evidence suggests that dysbiosis may influence central nervous system through gut-brain axis, potentially impacting behavior neurodevelopment. The use 16S rRNA gene sequencing become pivotal tool profiling microbial communities associated ASD, offering valuable insights into bacterial diversity, composition, potential functional roles. This review aims provide comprehensive analysis current findings on relationship between oral particular focus studies utilizing sequencing. We will explore how microbiome alterations contribute ASD pathophysiology, discuss limitations existing research, propose future directions for integration diagnostics treatment strategies. These underscore modulating symptoms. data suggest specific taxa are consistently altered which have implications understanding axis its

Language: Английский

Citations

1