Exposomics: a review of methodologies, applications, and future directions in molecular medicine DOI Creative Commons
Melissa Wan, Elisabeth M. Simonin,

Mary Johnson

et al.

EMBO Molecular Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

Abstract The exposome is the measure of all exposures an individual in a lifetime and how those relate to health. Exposomics emerging field research study totality exposome. can assist with molecular medicine by furthering our understanding influences cellular processes such as gene expression, epigenetic modifications, metabolic pathways, immune responses. These alterations aid biomarkers for diagnosis, disease prediction, early detection, treatment offering new avenues personalized medicine. Advances high throughput omics other technologies well increased computational analytics enabling comprehensive measurement sophisticated analysis elucidate their cumulative combined impacts on health, which enable individuals, communities, policymakers create programs, policies, protections that promote healthier environments people. This review provides overview potential role exposomics medicine, covering its history, methodologies, current applications, future directions.

Language: Английский

Exposomics: a review of methodologies, applications, and future directions in molecular medicine DOI Creative Commons
Melissa Wan, Elisabeth M. Simonin,

Mary Johnson

et al.

EMBO Molecular Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

Abstract The exposome is the measure of all exposures an individual in a lifetime and how those relate to health. Exposomics emerging field research study totality exposome. can assist with molecular medicine by furthering our understanding influences cellular processes such as gene expression, epigenetic modifications, metabolic pathways, immune responses. These alterations aid biomarkers for diagnosis, disease prediction, early detection, treatment offering new avenues personalized medicine. Advances high throughput omics other technologies well increased computational analytics enabling comprehensive measurement sophisticated analysis elucidate their cumulative combined impacts on health, which enable individuals, communities, policymakers create programs, policies, protections that promote healthier environments people. This review provides overview potential role exposomics medicine, covering its history, methodologies, current applications, future directions.

Language: Английский

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