Rationale and design of the Self-TI Study protocol: a cross-sectional human papillomavirus self-testing pilot study among transgender adults in England DOI Creative Commons
Sarah S. Jackson, Stewart O’Callaghan,

Elanore Ward

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(7), P. e086099 - e086099

Published: July 1, 2024

Introduction Persistent infection with high-risk human papillomavirus (HPV) is the causal agent of several cancers including cervical, anal and oropharyngeal cancer. Transgender men transmasculine non-binary (TMNB) people a cervix are much less likely to undergo cervical cancer screening than cisgender women. women transfeminine (TWNB) assigned male at birth may be increased risk HPV. Both TMNB TWNB face many barriers HPV testing medical mistrust due stigma discrimination. Methods analysis The Self-TI Study (Self-TI) pilot study designed measure acceptability feasibility self-testing among transgender in England. aged 25–65 years, least 1 year testosterone, people, 18 years over, eligible participate. Participants self-collect up four samples: an oral rinse, first void urine sample, vaginal swab (if applicable) swab. participants asked have additional clinician-collected taken following their routine Cervical Screening Programme sample. take self-collection kit perform home mail samples back clinic. Acceptability assessed by self-administered online survey measured as proportion returned clinic from home. Ethics dissemination received ethical approval Research Committee Wales 4 review panel within Division Cancer Epidemiology Genetics US National Institute. was coproduced members community, who served authors, collaborators patient public involvement (PPI) group. Results this will shared community prior being published peer-reviewed journals PPI group help design results strategy. evidence generated could used inform larger, international community. Trial registration number NCT05883111 .

Language: Английский

Acceptability of self-sampling and self-testing for infections: a rapid systematic review on public users’ views DOI Creative Commons
Aleksandra Borek, Caity Roleston, Runa Lazzarino

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 20, 2025

Abstract Background Self-sampling and self-testing have been increasingly used for sexually transmitted infections (STIs) quickly became widespread during the COVID-19 pandemic. User acceptability, preferences, experiences are important factors affecting self-sampling/self-testing uptake. Understanding these is key to managing planning responses health emergencies. This review aimed identify user views related usability, motivations preferences infections. Methods We conducted a rapid systematic review. searched Medline, EMBASE, PsycINFO, CINAHL, Web of Science, limiting records those published in English between 2014 2023. also manually additional peer-reviewed grey literature. included reports public users’ on any symptomatic asymptomatic (except human papillomavirus) with qualitative, mixed-methods or survey data relevant aim. Data were extracted into tables qualitative findings coded NVivo. synthesised narratively. Results identified 194 eligible reports, including 64 from Europe (which we prioritised detailed synthesis) 130 outside Europe. In Europe, studied respiratory ( n = 42, 37 COVID-19), STIs/HIV/genital 20), hepatitis C 2). Findings indicate that users found acceptable across infection/sampling types, populations, settings, countries. Users wanted help determine infection status protect others. The main benefits privacy convenience, helping reduce potential stigma infections, (for COVID-19) informing behaviour (e.g., socialising, self-isolating) contributing research. Easier perform less invasive sampling approaches more acceptable. However, some participants reported challenges self-sampling/self-testing, such as not understanding instructions, pain/discomfort collecting samples, lack confidence interpreting results. Conclusions evidence acceptability SS/ST it different approaches, populations. Evidence shows most people experience willing accept discomfort favour several perceived benefits. amenability could be leveraged diagnosing preventing transmission. It can support viability new models clinical care pandemic preparedness. Trial registration was pre-registered PROSPERO (ref. CRD42024507656 ).

Language: Английский

Citations

0
Quality, acceptability and usability of self-sampling kits used by non-healthcare professionals for STI diagnosis in Spain: a single-blind study DOI
Javier Gómez‐Castellá,

Marta Cobos Briz,

Néstor Nuño Martínez

et al.

Sexually Transmitted Infections, Journal Year: 2024, Volume and Issue: 100(7), P. 405 - 410

Published: July 4, 2024

Sexually transmitted infections (STIs) have markedly increased over the last decade in Spain, calling for prevention and control innovative approaches. While there is evidence indicating effectiveness of self-sampling STI diagnosis, no kits this purpose been authorised Spain.

Language: Английский

Citations

1
Implementation and user satisfaction of a comprehensive telemedicine approach for severe acute respiratory syndrome coronavirus 2 self-sampling: a monocentric, prospective, interventional, open-label, controlled, two-arm feasibility study (Preprint) DOI Creative Commons
Florian Voit, Johanna Erber, Silvia Egert-Schwender

et al.

JMIR Formative Research, Journal Year: 2024, Volume and Issue: 8, P. e57608 - e57608

Published: Sept. 5, 2024

The universal availability of smartphones has created new opportunities for innovative telemedicine applications in health care. COVID-19 pandemic heightened the demand contactless care services, making SARS-CoV-2 polymerase chain reaction (PCR) testing a crucial component containment.

Language: Английский

Citations

1
Rationale and design of the Self-TI Study protocol: a cross-sectional human papillomavirus self-testing pilot study among transgender adults in England DOI Creative Commons
Sarah S. Jackson, Stewart O’Callaghan,

Elanore Ward

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(7), P. e086099 - e086099

Published: July 1, 2024

Introduction Persistent infection with high-risk human papillomavirus (HPV) is the causal agent of several cancers including cervical, anal and oropharyngeal cancer. Transgender men transmasculine non-binary (TMNB) people a cervix are much less likely to undergo cervical cancer screening than cisgender women. women transfeminine (TWNB) assigned male at birth may be increased risk HPV. Both TMNB TWNB face many barriers HPV testing medical mistrust due stigma discrimination. Methods analysis The Self-TI Study (Self-TI) pilot study designed measure acceptability feasibility self-testing among transgender in England. aged 25–65 years, least 1 year testosterone, people, 18 years over, eligible participate. Participants self-collect up four samples: an oral rinse, first void urine sample, vaginal swab (if applicable) swab. participants asked have additional clinician-collected taken following their routine Cervical Screening Programme sample. take self-collection kit perform home mail samples back clinic. Acceptability assessed by self-administered online survey measured as proportion returned clinic from home. Ethics dissemination received ethical approval Research Committee Wales 4 review panel within Division Cancer Epidemiology Genetics US National Institute. was coproduced members community, who served authors, collaborators patient public involvement (PPI) group. Results this will shared community prior being published peer-reviewed journals PPI group help design results strategy. evidence generated could used inform larger, international community. Trial registration number NCT05883111 .

Language: Английский

Citations

0