AMBIO,
Journal Year:
2020,
Volume and Issue:
50(4), P. 812 - 821
Published: Dec. 7, 2020
Abstract
The
COVID-19
pandemic
is
a
global
crisis
emanating
both
from
virus
(SARS-CoV-2)
and
the
drastic
actions
to
contain
it.
Here,
we
reflect
on
immediate
responses
of
most
world
powers
amid
chaos:
totalitarian
surveillance
nationalist
isolation.
Drawing
published
literature,
consider
measures
such
as
wildlife-use
bans,
lockdowns
travel
restrictions,
along
with
their
reverberations
for
people,
economies
planet.
Our
synthesis
highlights
significant
shortfalls
applying
command-and-control
tactics
in
emergencies.
For
one,
heavy-handed
bans
risk
enormous
unintended
consequences
tend
fail
if
they
lack
legitimacy
or
clash
people’s
values.
Furthermore,
reactive
myopic
strategies
typically
view
stand-alone
crisis,
rather
than
unravelling
complex
interplay
nature-society
interactions
through
which
zoonotic
diseases
originate.
A
return
adaptive
management
approaches
that
recognise
root
causes
foster
socio-ecological
resilience
will
be
essential
improve
human
planetary
health
mitigate
future
pandemics.
Nature Communications,
Journal Year:
2021,
Volume and Issue:
12(1)
Published: June 14, 2021
Abstract
Improved
understanding
of
the
effects
meteorological
conditions
on
transmission
SARS-CoV-2,
causative
agent
for
COVID-19
disease,
is
needed.
Here,
we
estimate
relationship
between
air
temperature,
specific
humidity,
and
ultraviolet
radiation
SARS-CoV-2
in
2669
U.S.
counties
with
abundant
reported
cases
from
March
15
to
December
31,
2020.
Specifically,
quantify
associations
daily
mean
estimates
reproduction
number
(
R
t
)
calculate
fraction
attributable
these
conditions.
Lower
temperature
(within
20–40
°C
range),
lower
were
significantly
associated
increased
.
The
3.73%
(95%
empirical
confidence
interval
[eCI]:
3.66–3.76%),
9.35%
eCI:
9.27–9.39%),
4.44%
4.38–4.47%),
respectively.
In
total,
17.5%
was
factors.
fractions
factors
generally
higher
northern
than
southern
counties.
Our
findings
indicate
that
cold
dry
weather
low
levels
are
moderately
transmissibility,
humidity
playing
largest
role.
Proceedings of the National Academy of Sciences,
Journal Year:
2021,
Volume and Issue:
118(25)
Published: June 8, 2021
As
COVID-19
continues
to
spread
across
the
world,
it
is
increasingly
important
understand
factors
that
influence
its
transmission.
Seasonal
variation
driven
by
responses
changing
environment
has
been
shown
affect
transmission
intensity
of
several
coronaviruses.
However,
impact
on
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
remains
largely
unknown,
and
thus
seasonal
a
source
uncertainty
in
forecasts
SARS-CoV-2
Here
we
address
this
issue
assessing
association
temperature,
humidity,
ultraviolet
radiation,
population
density
with
estimates
rate
(R).
Using
data
from
United
States,
explore
correlates
US
states
using
comparative
regression
integrative
epidemiological
modeling.
We
find
policy
intervention
("lockdown")
reductions
individuals'
mobility
are
major
predictors
rates,
but,
their
absence,
lower
temperatures
higher
densities
correlated
increased
Our
results
show
summer
weather
cannot
be
considered
substitute
for
mitigation
policies,
but
autumn
winter
may
lead
an
increase
absence
interventions
or
behavioral
changes.
outline
how
information
improve
forecasting
COVID-19,
reveal
future
dynamics,
inform
policies.
International Journal of Environmental Research and Public Health,
Journal Year:
2021,
Volume and Issue:
18(2), P. 396 - 396
Published: Jan. 6, 2021
Weather
and
climate
play
a
significant
role
in
infectious
disease
transmission,
through
changes
to
transmission
dynamics,
host
susceptibility
virus
survival
the
environment.
Exploring
association
of
weather
variables
COVID-19
is
vital
understanding
potential
for
seasonality
future
outbreaks
developing
early
warning
systems.
Previous
research
examined
effects
on
COVID-19,
but
findings
appeared
inconsistent.
This
review
aims
summarize
currently
available
literature
between
incidence
provide
possible
suggestions
weather-based
system
transmission.
Studies
eligible
inclusion
used
ecological
methods
evaluate
associations
(i.e.,
temperature,
humidity,
wind
speed
rainfall)
The
showed
that
temperature
was
reported
as
greatest
number
studies,
with
increasing
decreased
highest
range
0–17
°C.
Humidity
also
significantly
associated
incidence,
though
results
were
mixed,
studies
reporting
positive
negative
correlation.
A
interaction
humidity
reported.
Wind
rainfall
not
consistent
across
studies.
including
can
contribute
increased
particularly
winter
conditions
viability
virus.
While
there
less
indication
an
rainfall,
these
may
behavioral
decrease
exposure
risk
infection.
Understanding
implications
seasonal
variations
monitoring
control
essential
Nature Communications,
Journal Year:
2021,
Volume and Issue:
12(1)
Published: Oct. 13, 2021
Abstract
There
is
conflicting
evidence
on
the
influence
of
weather
COVID-19
transmission.
Our
aim
to
estimate
weather-dependent
signatures
in
early
phase
pandemic,
while
controlling
for
socio-economic
factors
and
non-pharmaceutical
interventions.
We
identify
a
modest
non-linear
association
between
mean
temperature
effective
reproduction
number
(R
e
)
409
cities
26
countries,
with
decrease
0.087
(95%
CI:
0.025;
0.148)
10
°C
increase.
Early
interventions
have
greater
effect
R
0.285
CI
0.223;
0.347)
5th
-
95th
percentile
increase
government
response
index.
The
variation
explained
by
6
times
than
temperature.
find
little
meteorological
conditions
having
influenced
stages
local
epidemics
conclude
that
population
behaviour
are
more
important
drivers
Molecules,
Journal Year:
2020,
Volume and Issue:
25(19), P. 4410 - 4410
Published: Sept. 25, 2020
Fighting
infectious
diseases,
particularly
viral
infections,
is
a
demanding
task
for
human
health.
Targeting
the
pathogens
or
targeting
host
are
different
strategies,
but
with
an
identical
purpose,
i.e.,
to
curb
pathogen’s
spreading
and
cure
illness.
It
appears
that
increase
tolerance
against
can
be
of
substantial
advantage
strategy
used
in
evolution.
Practically,
it
has
broader
protective
spectrum
than
only
specific
pathogens,
which
differ
terms
susceptibility.
Methods
applied
one
pandemic
even
effective
upcoming
pandemics
pathogens.
This
more
urgent
if
we
consider
possible
concomitance
two
respiratory
diseases
potential
multi-organ
afflictions
such
as
Coronavirus
disease
2019
(COVID-19)
seasonal
flu.
Melatonin
molecule
enhance
host’s
pathogen
invasions.
Due
its
antioxidant,
anti-inflammatory,
immunoregulatory
activities,
melatonin
capacity
reduce
severity
mortality
deadly
virus
infections
including
COVID-19.
synthesized
functions
mitochondria,
play
critical
role
infections.
Not
surprisingly,
synthesis
become
target
strategies
manipulate
mitochondrial
status.
For
example,
infection
switch
energy
metabolism
from
respiration
widely
anaerobic
glycolysis
plenty
oxygen
available
(the
Warburg
effect)
when
cell
cannot
generate
acetyl-coenzyme
A,
metabolite
required
biosynthesis.
Under
some
conditions,
aging,
gender,
predisposed
health
already
compromised
exposed
further
challenges,
lose
their
producing
sufficient
amounts
melatonin.
leads
reduced
support
makes
these
individuals
vulnerable
diseases.
Thus,
maintenance
function
by
supplementation
expected
beneficial
effects
on
outcome
Nature Communications,
Journal Year:
2021,
Volume and Issue:
12(1)
Published: Feb. 8, 2021
High
susceptibility
has
limited
the
role
of
climate
in
SARS-CoV-2
pandemic
to
date.
However,
understanding
a
possible
future
effect
climate,
as
declines
and
northern-hemisphere
winter
approaches,
is
an
important
open
question.
Here
we
use
epidemiological
model,
constrained
by
observations,
assess
sensitivity
disease
trajectories
local
conditions.
We
find
this
depends
on
both
population
efficacy
non-pharmaceutical
interventions
(NPIs)
reducing
transmission.
Assuming
high
susceptibility,
more
stringent
NPIs
may
be
required
minimize
outbreak
risk
months.
Our
results
suggest
that
strength
remain
greatest
determinant
pre-vaccination
size.
While
small
for
meteorological
forecasts
projecting
severity,
uncertainty
parameters
will
likely
have
substantial
impact
generating
accurate
predictions.