Circadian Rhythm and Personalized Exercise DOI
Jiao Wang,

Li Shen,

Yuxin Zhang

et al.

Published: Jan. 1, 2022

Almost all physiological and biochemical processes in the human body follow a circadian rhythm. Studies have found that biological rhythms of body, especially rhythms, affect capacity for performance exercise. Exercise also affects rhythms. The rhythm influences core temperature, muscle strength, aerobic anaerobic exercise capacity, flexibility. causes phase shift remodels Research has shown can improve fitness if it is timed to coincide with peak performance. In addition considering diurnal variations, preferences regarding time (day or night) are important studying effects on Furthermore, there differences among different types. Therefore, arranging intensity according characteristics great significance improving training efficiency, reducing occurrence injuries, overcoming clock disorders.

Language: Английский

The Relationship between Circadian Rhythm and Cancer Disease DOI Open Access
Camelia Munteanu,

Sabina Turti,

Larisa Achim

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 5846 - 5846

Published: May 28, 2024

The circadian clock regulates biological cycles across species and is crucial for physiological activities biochemical reactions, including cancer onset development. interplay between the rhythm involves regulating cell division, DNA repair, immune function, hormonal balance, potential chronotherapy. This highlights importance of maintaining a healthy prevention treatment. article investigates complex relationship cancer, exploring how disruptions to internal may contribute tumorigenesis influence progression. Numerous databases are utilized conduct searches articles, such as NCBI, MEDLINE, Scopus. keywords used throughout academic archives “circadian rhythm”, ”cancer”, ”circadian clock”. Maintaining cycle prioritizing sleep habits minimizing disruptions, consistent schedules, reduced artificial light exposure, meal timing adjustments. Dysregulation gene can cause tumor growth, leading need regulate better treatment outcomes. components significantly impact cellular responses damage, influencing Understanding rhythm’s role in diseases their therapeutic targets essential treating preventing cancer. Disruptions promote abnormal development metastasis, potentially due system imbalances fluctuations.

Language: Английский

Citations

13
Shift work with and without night shifts and breast cancer risk in a cohort study from Finland DOI Creative Commons
Mikko Härmä,

Anneli Ojajärvi,

Aki Koskinen

et al.

Occupational and Environmental Medicine, Journal Year: 2022, Volume and Issue: 80(1), P. 1 - 6

Published: Aug. 10, 2022

Objectives To examine the association of shift work with and without night breast cancer among women in public sector. Methods Using Finnish Public Sector cohort study (N=33 359, mean age 40.6 years at baseline), we investigated associations potential confounders incident cancer. Exposure to permanent day or was defined from first two consecutive surveys 2000, 2004, 2008 2012 past information on exposure a subcohort (n=20 786). Incident cases (n=1129) were retrieved National Cancer Register members followed end 2016. HR 95% CI Cox proportional hazard regression models calculated. Results Shift shifts not overall associated When stratified according age, both nights (HR 2.01, 1.12 3.60) (OR 2.05, 1.04 4.01) an increased risk after period 10 more follow-up aged 50 older, when adjusted for socioeconomic status, children, smoking, alcohol body mass index. In subgroup work, by longer significant. Conclusions This provides support elderly workers. However, insufficient intensity may attenuate estimates.

Language: Английский

Citations

17
Social and professional recognition are key determinants of quality of life at work among night-shift healthcare workers in Paris public hospitals (AP-HP ALADDIN COVID-19 survey) DOI Creative Commons
Martin Duracinský, Fabienne Marcellin, Lorraine Cousin

et al.

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(4), P. e0265724 - e0265724

Published: April 7, 2022

Objective Documenting the perceptions and experiences of frontline healthcare workers during a sanitary crisis is key to reinforce systems. We identify determinants quality working life (QWL) among night-shift (NSHW) in Paris public hospitals shortly after first-wave COVID-19 pandemic. Methods The ALADDIN cross-sectional online survey (15 June 15 September 2020) collected QWL, socio-economic, behavioral, work-related information 1,387 NSHW 39 Assistance Publique—Hôpitaux de (AP-HP). Data were weighted (margin calibration) be representative entire population 12,000 AP-HP hospitals’ regarding sex, age, professional category. Linear regression was used correlates QWL (WRQoL scale). Results New night position COVID pandemic, difficulties getting screened for COVID, considering protective measures inadequate associated with poorer adjustment socio-economic characteristics, category, perceived health, physical activity, history harassment at work. Under-estimation work by day-shift colleagues, reporting as source tension friends, or feeling more irritable since also impaired QWL. By contrast, satisfaction received from employer, valued general pandemic improved Conclusions Insufficient access screening, information, first wave hospitals. Social recognition this population.

Language: Английский

Citations

13
Night shift work and breast cancer risk – 2023 update of epidemiologic evidence DOI Creative Commons
Johnni Hansen, Julie Elbæk Pedersen

Journal of the National Cancer Center, Journal Year: 2024, Volume and Issue: 5(1), P. 94 - 103

Published: Sept. 25, 2024

Language: Английский

Citations

2
The relationship between night shift work and breast cancer incidence: A systematic review and meta-analysis of observational studies DOI Creative Commons
Jiaze Hong, Yujing He,

Rongrong Fu

et al.

Open Medicine, Journal Year: 2022, Volume and Issue: 17(1), P. 712 - 731

Published: Jan. 1, 2022

The purpose of this study was to investigate the relationship between night shift work and breast cancer (BC) incidence. A search performed in PubMed, EBSCO, Web Science, Cochrane Library databases before June 2021. exposure factor is work, primary outcome risk BC. total 33 observational studies composed 4,331,782 participants were included. Night increases BC female population (hazard ratio [HR] = 1.20, 95% confidence interval [Cl] 1.10-1.31, p < 0.001), especially receptor-positive BC, including estrogen receptor (ER)+ (HR 1.35, progesterone (PR)+ 1.30, 0.003), human epidermal growth 2 (HER2)+ 1.42, but has no effect on HER2- 1.10, 0.515) ER-/PR- 0.98, 0.827). positively correlated with working duration, frequency, cumulative times. For women who start menopause, will increase incidence 1.17, 0.020), for after does not affect 1.04, 0.293). can population. long hours, number shifts influenced by menopausal status.

Language: Английский

Citations

11
Night work and breast cancer risk in a cohort of female healthcare employees in Stockholm, Sweden DOI Creative Commons
Per Gustavsson, Carolina Bigert, Tomas Andersson

et al.

Occupational and Environmental Medicine, Journal Year: 2023, Volume and Issue: 80(7), P. 372 - 376

Published: May 3, 2023

Objectives Night work has been classified as probably carcinogenic to humans by the International Agency for Research on Cancer, but epidemiological evidence was considered limited due variability in findings and potential bias. This study aimed investigate risk of breast cancer a cohort with detailed registry-based data night work. Methods The comprised 25 585 women (nurses nursing assistants) employed 1 year or more between 2008 2016 healthcare sector Stockholm. Information schedules obtained from employment records. Breast cases were identified national register. HRs estimated discrete time proportional hazards model, adjusting age, country birth, profession childbirth. Results There 299 cancer, 147 premenopausal 152 postmenopausal women. adjusted HR association ever versus never working nights 1.31 (95% CI 0.91 1.85). Eight years associated an increased HR=4.33 1.45 10.57), based five only, though. Conclusions is short period follow-up lack information before 2008. Most exposure metrics showed no risk, there elevated after 8

Language: Английский

Citations

6
Considering the impact of shift working on health DOI

Faye Bostock,

Gerri Mortimore

British Journal of Nursing, Journal Year: 2024, Volume and Issue: 33(3), P. 120 - 124

Published: Feb. 8, 2024

Shift work is necessary for the provision of health services, especially in hospitals as it only way to provide continuous care patients. Working at night inconsistent with body's biological clock and shift working hugely disrupts circadian sleep wake cycles. In 2020, World Health Organization classified being a ‘probable’ class 2A carcinogen number independent cohort studies both workers have observed increased incidence certain cancers. Altered timing, food timing light exposure typical leads an acute disruption misalignment regulatory hormones. This straying from synchronisation has been shown result individuals more vulnerable chronic conditions. Night normal sleep–wake cycle, often leading shortened duration excessive fatigue results this are far reaching. article will explore full impact working, questioning if current practices employed within NHS should continue.

Language: Английский

Citations

1
Night shift work and female breast cancer: a two-stage dose-response meta-analysis for the correct risk definition DOI Creative Commons
Jinyoung Moon, Atsuko Araki, Yongseok Mun

et al.

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: July 31, 2024

Abstract Introduction The hypothesis of this study is night shift work exposure can increase the risk female breast cancer. To validate hypothesis, authors conducted a two-stage dose-response meta-analysis with improved quality on topic. Methods medical librarian searched PubMed, EMBASE, and Cochrane Library December 30th, 2022. eight inclusion criteria were determined strictly applied to selection process. A reliable methodology was applied. Results Reliable 10 cohort (total cases: 15,953, total person-years: 6,812,138) 11 case-control reports 9196, controls:12,210) included in final analysis. pooled ratio (RR) cancer (from studies) for 1, 10, 20, 30 years 1.0042 (95% CI 1.0014–1.0070), 1.0425 1.0138–1.0719), 1.0867 1.0278–1.1490), 1.1328 1.0419–1.2317), respectively. odds (OR) 1.0213 1.0108–1.0319), 1.2346 1.1129–1.3695), 1.5242 1.2386–1.8756), 1.8817 1.3784–2.5687), Discussion This has several strengths from perspective meta-analysis: Strictly criteria, separately synthesized RRs studies ORs studies, clearly defined dose, each estimate, methodology, careful considering selection, exposure, outcome biases confounder adjustment study. consideration potential confounding led exclusion unreliable two five studies.

Language: Английский

Citations

1
Sickness absence among employees of healthcare organizations in the public sector in Mongolia: A cross-sectional study DOI Creative Commons
Erdenetuya Sukhee,

Tugsdelger Sovd,

Ulzii-orshikh Khaltar

et al.

Journal of Occupational Health, Journal Year: 2023, Volume and Issue: 65(1)

Published: Jan. 1, 2023

Abstract Objectives This study aimed to understand the rate of sickness absence (SA) among employees public healthcare organizations in Mongolia, identify factors associated with long-term SA, and estimate costs due SA. Methods cross-sectional included who had certified SA from 2016 2018. Sociodemographic occupational characteristics absentees data on absences were collected. A logistic regression analysis was performed (≥15 days) Absence parameters average calculated total cost at all estimated. Results From 2018, there 13 653 21 043 0.9%. The length per absentee 9.63 days 14.85 days, respectively. Factors age ≥40 years, 10–19 years employment, working second tertiary levels, night shift. 295.5 USD, estimated for health 1 796 993 USD year. Conclusions 0.9% older age, longer work experience, higher organizational level, shift taking a To reduce absenteeism promote organizations, policymakers should review policies related develop national guidelines employers, managers, employees.

Language: Английский

Citations

3
Sex and gender differences in sleep disorders: An overview DOI
Fidaa Shaib, Hrayr Attarian

Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 661 - 679

Published: Jan. 1, 2023

Citations

3