Toxicology Reports,
Journal Year:
2023,
Volume and Issue:
10, P. 554 - 570
Published: Jan. 1, 2023
Increased
exposure
to
environmental
heavy
metals
and
metalloids
their
associated
toxicities
has
become
a
major
threat
human
health.
Hence,
the
association
of
these
with
chronic,
age-related
metabolic
disorders
gained
much
interest.
The
underlying
molecular
mechanisms
that
mediate
effects
are
often
complex
incompletely
understood.
In
this
review,
we
summarize
currently
known
disease-associated
signaling
pathways
altered
following
different
exposure,
alongside
brief
summary
impacts.
main
focus
study
is
explore
how
affected
chronic
multifactorial
diseases
including
diabetes,
cardiovascular
diseases,
cancer,
neurodegeneration,
inflammation,
allergic
responses
upon
arsenic
(As),
cadmium
(Cd),
chromium
(Cr),
iron
(Fe),
mercury
(Hg),
nickel
(Ni),
vanadium
(V).
Although
there
considerable
overlap
among
metalloids-affected
cellular
pathways,
affect
distinct
as
well.
common
may
be
explored
further
find
targets
for
treatment
pathologic
conditions.
Geochemical Transactions,
Journal Year:
2024,
Volume and Issue:
25(1)
Published: Jan. 11, 2024
Abstract
Bardawil
Lake
is
a
unique
aquatic
ecosystem
that
provides
habitat
for
various
fish
and
other
marine
organisms.
This
study
aimed
to
analyze
the
quality
of
species
prove
this
lake
free
pollution,
not
Egyptian
lakes,
due
accumulation
some
heavy
metals
(Cd,
Pb,
Cu,
Zn)
in
tissues
were
caught
from
lake.
Thirty-five
samples
during
Spring
2018
seven
different
species:
Mugil
cephalus,
Liza
auratus,
Sparus
aurata,
Dicentrarchus
labrax,
Siganus
rivulatus,
Anguilla
angilla,
Solae
solea
.
The
Association
Official
Analytical
Chemists
methods
using
spectrophotometer
determined
biochemical
composition.
In
contrast,
atomic
absorption
spectrometry
(AAS)
was
employed
determine
expressed
by
µg/g
wet
weight.
Results
exposed
essential
micronutrient
(Cu,
content
higher
than
toxic
elements
(Cd
&
Pb)
muscles
order
Zn
>
Cu
Pb
Cd.
Muscles
<
gills
liver
all
except
with
gills.
studied
lower
those
set
WHO
EU
standards.
carcinogenic
risk
allowable
limits
1
×
10
–6
–4
both
normal
high
consumption
groups;
target
total
hazard
quotients
(THQ
HI)
1.
composition
level
highest
liver,
protein,
which
muscle
species.
There
no
evidence
harmful
contaminants
muscular
tissue
sampled
Lake,
although
fishing
activity.
However,
customers
should
know
health
concerns
may
be
associated
overeating
fish.
Water,
Journal Year:
2024,
Volume and Issue:
16(20), P. 2994 - 2994
Published: Oct. 20, 2024
The
bioaccumulation
of
trace
elements
and
heavy
metals
in
aquatic
organisms
is
a
critical
environmental
concern
due
to
its
potential
impact
on
ecosystem
health
human
safety.
This
study
investigated
the
level
Labeo
rohita
Mystus
seenghala
from
River
Jhelum
district
Khushab,
Punjab,
Pakistan.
concentration
calcium,
magnesium,
iron,
nickel,
copper,
arsenic,
cadmium,
zinc,
chromium,
manganese,
cobalt,
lead
gills,
liver,
muscle
tissues
these
fish
was
measured
using
inductively
coupled
plasma-mass
spectrometry.
Then,
extent
contamination
possible
risks
were
assayed.
Our
findings
indicate
significant
variations
elemental
metal
concentrations
among
different
organs
between
species,
reflecting
their
diverse
feeding
habits
habitats.
risk
assessment
based
estimated
daily
intake,
weekly
maximum
permissible
target
hazard
quotient,
index
or
total
index,
cancer
revealed
consumers
fish.
emphasizes
need
for
continuous
monitoring,
as
new
data
insights
are
crucial
understanding
mitigating
risks.
Strict
regulatory
measures
also
necessary
safeguard
public
preserve
River.
Journal of Xenobiotics,
Journal Year:
2025,
Volume and Issue:
15(2), P. 59 - 59
Published: April 18, 2025
Heavy
metal
contamination
in
marine
ecosystems
poses
a
critical
environmental
challenge,
with
significant
implications
for
biodiversity,
trophic
dynamics,
and
human
health.
Marine
fish
are
key
bioindicators
of
heavy
pollution
because
their
role
food
webs
capacity
bioaccumulation
transfer.
This
review
synthesizes
current
knowledge
on
the
pathways
mechanisms
accumulation
fish,
focusing
factors
that
influence
uptake,
retention,
tissue
distribution.
We
explore
processes
governing
transfer
biomagnification,
highlighting
species-specific
patterns
risks
posed
to
apex
predators,
including
humans.
Additionally,
we
assess
ecological
consequences
at
population,
community,
ecosystem
levels,
emphasizing
its
effects
reproduction,
community
structure,
interactions.
By
integrating
recent
findings,
this
highlights
gaps
suggests
future
research
directions
improve
monitoring
risk
assessment.
Given
persistence
bioavailability
metals
environments,
effective
control
strategies
sustainable
fisheries
management
imperative
mitigate
long-term
public
health
risks.
FUDMA Journal of Sciences,
Journal Year:
2025,
Volume and Issue:
9(1), P. 366 - 372
Published: April 16, 2025
This
study
aimed
to
assess
the
accumulation
level
of
Cadmium
(Cd),
Zinc
(Zn),
Lead
(Pb),
Copper
(Cu),
Iron
(Fe),
and
Manganese
(Mn)
in
two
organs
(gills
muscle)
fish
species
(Ethmalosa
fimbriata
Chrysichthys
macropogon)
from
four
coastal
towns
(Ayetoro,
Bijimi,
Idiogba
Asumogha)
Ilaje
Local
Government
Area,
Ondo
State,
Nigeria.
Fish
samples
used
were
collected
monthly
for
a
period
months
stations
using
gillnet
with
mesh
sizes
0.6cm,
1.0cm,
2.0cm,
3.0cm
4.0cm
throughout
study.
The
digested
heavy
metal
concentration
was
analyze
Atomic
Absorption
Spectrophotometer
(Model
AA240FS).
Concentrations
both
occurred
order:
Fe>Mn>Zn>Cu>Pb>Cd.
Heavy
higher
gills
compared
muscles
where
metabolic
activity
is
relatively
lower.
across
varied
0.328
0.923
mg/kg.
Zn
fishes
ranged
1.644±0.53
2.095±0.26
while
cadmium
concentrations
muscle
gill
E.
0.003±0.00
0.355±0.41.
Bio-accumulation
C.
macropogon
area
shows
aquatic
pollution.
