Effectiveness and safety of COVID-19 vaccines on maternal and perinatal outcomes: a systematic review and meta-analysis

BMJ Global Health, Journal Year: 2024, Volume and Issue: 9(4), P. e014247 - e014247

Published: April 1, 2024

Objective To assess the effects of COVID-19 vaccines in women before or during pregnancy on SARS-CoV-2 infection-related, pregnancy, offspring and reactogenicity outcomes. Design Systematic review meta-analysis. Data sources Major databases between December 2019 January 2023. Study selection Nine pairs reviewers contributed to study selection. We included test-negative designs, comparative cohorts randomised trials infection-related Non-comparative cohort studies reporting outcomes were also included. Quality assessment, data extraction analysis Two independently assessed quality extracted data. undertook random-effects meta-analysis reported findings as HRs, risk ratios (RRs), ORs rates with 95% CIs. Results Sixty-seven (1 813 947 women) Overall, design studies, pregnant fully vaccinated any vaccine had 61% reduced odds infection (OR 0.39, CI 0.21 0.75; 4 23 927 women; I 2 =87.2%) 94% hospital admission 0.06, 0.01 0.71; 868 =92%). In adjusted hypertensive disorders was by 12% (RR 0.88, 0.82 0.92; studies; 115 085 women), while caesarean section 9% 0.91, 0.85 0.98; 6 30 192 women). observed an 8% reduction neonatal intensive care unit 0.92, 0.87 0.97; 54 569 babies born versus not women. general, vaccination associated increased adverse perinatal Pain at injection site most common side effect (77%, 52% 94%; 11 27 195 Conclusion are effective preventing related complications PROSPERO registration number CRD42020178076.

Language: Английский

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A scoping review of global COVID-19 vaccine hesitancy among pregnant persons

npj Vaccines, Journal Year: 2024, Volume and Issue: 9(1)

Published: July 20, 2024

Abstract Uptake of the COVID-19 vaccine among pregnant persons is lower than general population. This scoping review explored people’s attitudes towards vaccine, reasons for hesitancy, and whether about vaccines differ by country origin. A was conducted across PubMed, Embase, CINHAL, Scopus. Inclusion criteria were articles published in English from 2019–2022 focused on vaccination persons. Data analysis done via 5Cs framework hesitancy: Constraints, Complacency, Calculation, Confidence, Collective Responsibility. 44 extracted. lack confidence safety most prevalent theme hesitancy largely driven a access to information as well mistrust medical professionals. Meanwhile, acceptance mostly desire protect themselves their loved ones. Overall, continues be high. Vaccine primarily fear unknown side effects fetuses along with mistrust. Some differences can seen between high income low- middle-income countries regarding showing that single solution cannot applied all who are hesitant. General strategies, however, utilized reduce including advocating inclusion clinical trials incorporating consistent counseling during prenatal appointments.

Language: Английский

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Maternal Vaccination and Neonatal Feeding Strategies Among Polish Women

Vaccines, Journal Year: 2025, Volume and Issue: 13(4), P. 376 - 376

Published: March 31, 2025

Background/Objectives: Maternal vaccination and breastfeeding are important aspects of public health that should be recommended by medical staff caring for pregnant postpartum women. We aimed to analyze factors affecting women’s likelihood dual during pregnancy their infant feeding strategies. Methods: A cross-sectional study was conducted with 953 Polish mothers. An online questionnaire used included questions on sociodemographic obstetric variables, attitudes towards COVID-19 influenza vaccination, practices. Results: reported 66.0%, 18.2%, 15.6% Increasing willingness receive vaccines significantly associated older maternal age, lower BMI, living in urban areas >100,000 residents, high levels knowledge regarding vaccination. No significant association between neonatal strategy detected. The group exclusively mothers, comparison formula- mixed-feeding women, characterized having pre-pregnancy BMI previous experience. Conclusions: Rates against seasonal (influenza COVID-19) remain low among promotion antenatal reliable information about short- long-term advantages related crucial perinatal care the mother–infant dyad. Young, primiparous women who overweight or obese targets preventive programs focused

Language: Английский

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Maternal Vaccination in Pregnancy: An Assessment of Influenza, Pertussis, and COVID-19 Vaccination Rates in Cracow, Poland

Medical Science Monitor, Journal Year: 2024, Volume and Issue: 30

Published: Jan. 22, 2024

BACKGROUND:Maternal vaccination during pregnancy reduces the risk of severe course and complications from infections both for mother her child. As information regarding immunization status pregnant women with recommended vaccines in Poland is scarce, this questionnaire-based study aimed to identify influenza, pertussis (whooping cough), COVID-19 205 Cracow, Poland, between February April 2023. Another objective was assess whether any maternal factors might influence women's decision inoculate pregnancy. MATERIAL AND METHODS:An anonymous self-reported questionnaire developed specifically disseminated among postpartum women, who gave birth were hospitalized at Department Obstetrics Perinatology University Hospital Study participants asked about their basic sociodemographic obstetric data, as well pertussis, most recent RESULTS:Only 12.2% 23.4% received influenza vaccinations, respectively, pregnancy, while 61.5% reported least 2 doses mRNA vaccine. Features including type occupation, place residence, gravidity, parity statistically significant (P<0.05) influencing likelihood vaccination. CONCLUSIONS:Influenza coverage suboptimal lower than observed other countries, rates are on par global trends.

Language: Английский

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Vaccination during pregnancy: A golden opportunity to embrace

International Journal of Gynecology & Obstetrics, Journal Year: 2023, Volume and Issue: 163(2), P. 476 - 483

Published: July 7, 2023

Language: Английский

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COVID-19 Vaccine Acceptance Among Pregnant, Lactating, and Nonpregnant Women of Reproductive Age in Turkey: A Cross-Sectional Analytical Study

Disaster Medicine and Public Health Preparedness, Journal Year: 2023, Volume and Issue: 17

Published: Jan. 1, 2023

This study aims to identify the rates of coronavirus disease 2019 (COVID-19) vaccine acceptance, reasons for receiving and not vaccine, associated factors among pregnant, lactating, nonpregnant women reproductive age.This cross-sectional analytical was conducted online in Turkey, at end fourth wave COVID-19 pandemic, between February May 2022. A total 658 (230; 35% pregnant) (187; 28.4% lactating) (241; 36.6% nonpregnant) age participated study.Vaccine acceptance were found be 91.7% age, 77% lactating women, 59% pregnant (P < 0.05). The highest rate hesitancy observed (31.3%), rejection (10.2%). Pregnancy (odds ratio [OR] = 3.98; confidence interval [CI] 1.13-14.10), breastfeeding period (OR 3.84; CI 1.15-12.78), increased approximately four times.Lack knowledge about is still one barriers today. Health-care providers (HCPs) should provide effective counseling reproductive-aged based on current information guidelines.

Language: Английский

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A Scoping Review on Gender/Sex Differences in COVID-19 Vaccine Intentions and Uptake in the United States

American Journal of Health Promotion, Journal Year: 2023, Volume and Issue: 38(2), P. 242 - 274

Published: Oct. 17, 2023

Objective To explore the empirical literature on gender/sex differences in vaccine acceptance among U.S.-based adults and adolescents approximately first 2 years of pandemic. Data source Embase, Medline, PsycINFO, EBSCO, CINAHL, Web Science Study inclusion exclusion criteria Peer-reviewed studies conducted U.S. with those aged 12 older, published English before January 12, 2022, examining relationship between COVID-19 intentions and/or uptake. extraction Three authors screened extracted data. Synthesis Univariate multivariate results are summarized. Results A total 53 met (48 intentions, 7 uptake), using mostly cross-sectional designs (92.5%) non-random sampling (83.0%). The majority supported men’s greater to vaccinate compared women, uptake univariate analyses, but most analyses no gender Few examined beyond binary categories (women/men), highlighting a gap inclusive transgender or gender-diverse populations analyses. Conclusion Women may have been more hesitant get than men early pandemic, these not translate actual behavior. Future research should include non-binary/transgender populations, gender-specific reasons for hesitancy by sub-populations, utilize rigorous designs, test gender-sensitive public health campaigns mitigate concerns.

Language: Английский

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COVID-19 Vaccine Acceptance during Pregnancy: Lessons Learned and How to Design the Best Strategy to Increase Vaccination Acceptance in the Future

Archives of Obstetrics and Gynaecology, Journal Year: 2023, Volume and Issue: 4(1), P. 18 - 27

Published: March 6, 2023

Objective: The present study aimed to the vaccination acceptance of COVID-19 vaccine in Hellenic pregnant population and make a high relative analysis factors that contribute decision-making concerning during pregnancy. Findings could be leveraged for improving communication strategy women increase rate. Study design: is prospective cross-sectional conducted from October 1, 2021 until March 2022 800 receiving prenatal care at tertiary University Hospital. Data was gathered through face-to-face questionnaire documented via official certificate. Results: coverage rate 53.9%. Employment, older age, higher monthly income were significantly positively associated with (p<0.001). Information provided by health professionals (p=0.004) scientific sites (p=0.028); sufficient knowledge vaccines also related (p<0.001); pediatric their children family (p=0.003); against influenza pregnancy (past: p<0.001 pregnancy: p<0.001); pertussis (present p<0.001) vaccination. Intention vaccinate future all recommended vaccines; belief safety protects serious diseases acceptance. Reduced hesitancy due pandemic; fear severity infection (p<0.001 each case) Conclusion: In conclusion we need improve women, focusing more on effectiveness data, sharing information about surveillance programs, using clinical experience other maternal vaccination, presenting benefits mother offspring.

Language: Английский

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COVID‐19 vaccination in pregnancy: A quantitative and qualitative analysis of the effect of strong public health messaging in an Australian cohort

Australian and New Zealand Journal of Obstetrics and Gynaecology, Journal Year: 2024, Volume and Issue: 64(6), P. 580 - 587

Published: May 22, 2024

SARS-CoV-2 infection in pregnancy predisposes women and their offspring to adverse health outcomes, while internationally reported rates of vaccination uptake remain low. Our study objective was quantify the COVID-19 pregnant women, assess attitudes toward with both quantitative qualitative analyses.

Language: Английский

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An investigation of the relationship between the general vaccination attitudes of pregnant women and their attitudes toward the COVID-19 vaccine

Women & Health, Journal Year: 2023, Volume and Issue: 63(10), P. 787 - 796

Published: Oct. 23, 2023

This study aimed to investigate the relationship between attitudes of pregnant women toward general vaccines based on Health Belief Model and their COVID-19 vaccine. The study, which was designed as a descriptive, cross-sectional, correlational conducted with 348 in three public hospitals Northern Cyprus June 24 November 28, 2022. Data were collected using "Participant Information Form," "Public Attitude Toward Vaccination Scale-Health Model" (PAVS-HBM), "Attitudes Vaccine" (ATV-COVID-19). vaccination rate among quite high. Pregnant have high perception sensitivity, importance, benefit, health responsibility for routine programs HBM, low barriers vaccination. These results showed that determined positive attitude acceptance general. On other hand, vaccine moderately negative. Despite reservations about vaccine, has increased

Language: Английский

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