Efficacy of Pulmonary Rehabilitation in Post-COVID-19: A Systematic Review and Meta-Analysis

Biomedicines, Journal Year: 2023, Volume and Issue: 11(8), P. 2213 - 2213

Published: Aug. 7, 2023

This systematic review and meta-analysis examines how pulmonary rehabilitation impacts in patients suffering from subacute long COVID-19 infections, gauging enhancements of dyspnea, physical function, quality life, psychological state (anxiety depression), fatigue.

Language: Английский

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The pulmonary rehabilitation effect on long covid‐19 syndrome: A systematic review and meta‐analysis

Physiotherapy Research International, Journal Year: 2024, Volume and Issue: 29(2)

Published: Feb. 22, 2024

Abstract Objectives This systematic review and meta‐analysis aims to evaluate the efficacy of pulmonary rehabilitation (PR) in improving dyspnea, fatigue, physical activity, quality life, anxiety depression patients with Long COVID‐19 (LC). The impact PR on LC a comparison face‐to‐face telerehabilitation approaches was explored. Methods followed PRISMA guidelines registered PROSPERO. A literature search included PubMed, Web Science, Cochrane Library until January 2023. No language filters were applied. Randomized controlled trials, non‐randomized observational studies included. risk bias assessed using appropriate tools. Descriptive analysis performed. Forest plots presented results. Statistical analyses conducted Metafor Package R v.3.4.2. Results/Findings 16 patients. total 1027 adults varied design, seven studies, three quasi‐experimental six randomized trials. Dyspnea, function, psychological state, fatigue as outcomes. found that had significant positive effect life (both global domain), anxiety, depression. However, not significant. Heterogeneity observed some analyses, publication certain Age study design identified potential moderators. Both interventions improved studied outcomes, only differences domain favoring group. Implications Physiotherapy Practice state patients, but fatigue. Face‐to‐face have similar effects, except for life.

Language: Английский

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Pulmonary Rehabilitation in SARS-CoV-2: A Systematic Review and Meta-Analysis of Post-Acute Patients

Diagnostics, Journal Year: 2022, Volume and Issue: 12(12), P. 3032 - 3032

Published: Dec. 2, 2022

Background: Pulmonary Rehabilitation (PR) was initially developed for the management of Chronic Obstructive Disease (COPD) and is now recognized as a core COVID-19 patients. This systematic review meta-analysis examined efficacy PR in patients with post-acute infection. Methods: A literature search conducted PubMed, Web Science (WoS), Cochrane Library from their inceptions until October 2022, randomized controlled trials observational studies were considered. The outcomes measured included dyspnea, physical function, quality life. Results: Eleven including 677 participants this analysis. From qualitative point view analyzing separately, improves life COVID-19. However, pooling data all studies, no significant changes pre-postintervention, compared to control, found among experimental analysis any outcome measures, due high heterogeneity between well improvements being studies. subgroup revealed differences outcomes. Future should include same scale assess actual PR. Conclusion: view, effective improving reducing an exploratory performed evaluate, by subgroups, PR, positive results favor

Language: Английский

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Current landscape of long COVID clinical trials

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 132, P. 111930 - 111930

Published: March 27, 2024

Language: Английский

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Multicomponent Exercise Program to Avoid Productivity Loss Due to COVID-19

Topics in Geriatric Rehabilitation, Journal Year: 2024, Volume and Issue: 40(2), P. 175 - 183

Published: April 1, 2024

Objective: To evaluate and quantify the mitigation of productivity deficits in individuals recovering from post-COVID-19 conditions by implementing a multicomponent exercise program (MEP). Methods: Thirty-nine patients meeting specific criteria participated 7-week intervention involving cycloergometer interval training, strength exercises, respiratory physiotherapy. Follow-up assessments occurred 2 weeks post-intervention 23 months later via telephone interviews. The study computed average avoided loss to estimate indirect costs. Results: Over years, 51.4% had persistent symptoms 48.7% reported complex issues. Age differences were observed between retired employed individuals. Multinomial regression revealed 91.849 times higher likelihood simple signs 1.579 being older retirees. Simple associated with 90 000 returning work. Sensitivity analysis indicated potential gains €117 955 €134 004 per patient over 4-year horizon. Conclusion: MEP is safe effective post-COVID recovery intervention, notably aiding workforce reintegration for signs. Patients such significantly more likely return work, highlighting emphasizing need further research on program's cost-effectiveness broader societal benefits.

Language: Английский

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Knowledge, attitudes and practices regarding pulmonary rehabilitation among patients with chronic respiratory diseases: a cross-sectional questionnaire-based study in a tertiary hospital in China

BMJ Open, Journal Year: 2025, Volume and Issue: 15(1), P. e085944 - e085944

Published: Jan. 1, 2025

Objectives This study aimed to evaluate the knowledge, attitudes and practices (KAP) of patients with chronic respiratory diseases towards pulmonary rehabilitation. Design Cross-sectional, web-based questionnaire study. Setting Tertiary healthcare hospital in Taiyuan, Shanxi Province, China. Participants A total 511 were recruited from hospital’s outpatient inpatient departments. After data cleaning, 501 valid responses (98.04% response rate) analysed. aged 18 or older, able complete independently assistance included individuals diverse demographic backgrounds. Primary secondary outcome measures outcomes KAP scores related The assessed association between factors (age, gender, income, education, smoking status) using structural equation modelling (SEM). Results mean 1.26±2.85 for 30.46±3.63 34.58±5.55 practices. SEM analysis showed that knowledge directly influenced (β=−0.538, p<0.001) both (β=0.668, significantly Additionally, factors, such as monthly household type disease, educational level status associated variations (all p<0.05). Conclusions Patients demonstrated poor generally positive attitudes, moderate regarding Tailored interventions focusing on bridging gap promoting behavioural changes are essential improving rehabilitation engagement among disease patients. Trial registration number ChiCTR2400080271.

Language: Английский

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Cytokine profiles and neurological manifestations in post-COVID syndrome

Exploration of Immunology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Aim: The objectives of our study were to evaluate a range circulating biomarkers in COVID-19-related long-term neurological dysfunction. Methods: involved 30 patients with post-COVID syndrome (PCS) and 28 after COVID-19 without PCS. third cohort consisted 29 acute varying severity. severity was classified as mild moderate severe. Montreal Cognitive Assessment (MOCA) the SAGE test used cognitive functions. Hospital Anxiety Depression Scale (HADS), Sheehan Scale, Beck Inventory affective levels serum cytokines IgM, IgG, IgA SARS-CoV-2 coronavirus determined using Vector-Best systems (Novosibirsk, Russia). We also studied IgG subclasses spike protein SARS-CoV-2. Results: А infection primarily increases risk disorders asthenia and, lesser extent, development impairment. IFN-α, IL-6, well antibodies among PCS significantly higher compared convalescents IgM detected blood during 2–7 months disease. After severe COVID-19, IgG2 IgG4 predominant symptoms. IL-1, IL-4, IL-8 who had COVID-19. Conclusions: obtained data on an elevated level IFN-α can suggest hypothesis about participation chronic inflammation disorders. main limitation is relatively small sample size, which limits statistical analyses.

Language: Английский

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Addressing post-COVID-19 musculoskeletal symptoms through pulmonary rehabilitation with an evidence-based eHealth education tool: Preliminary results from a pilot randomized controlled clinical trial

Medicine, Journal Year: 2025, Volume and Issue: 104(10), P. e41583 - e41583

Published: March 7, 2025

The coronavirus disease (COVID-19) pandemic has led to a global health crisis with significant long-term consequences, including musculoskeletal symptoms such as fatigue, myalgia, and chronic pain. These issues, often linked altered nociceptive processing, impair quality of life are exacerbated in severe cases by intensive care unit-acquired weakness from immobilization mechanical ventilation. Early rehabilitation, particularly pulmonary rehabilitation (PR), is crucial for mitigating these effects. Telerehabilitation, leveraging telemedicine, offers an innovative, accessible alternative, providing personalized programs that improve adherence recovery. Recent studies highlight telerehabilitation's benefits alongside traditional methods, underscoring its potential managing post-COVID-19 sequelae. This study aimed evaluate the effects PR eHealth education tool (ET) on pain, functionality, life, psychological factors patients compare telerehabilitation versus face-to-face approaches regarding treatment adherence. pilot randomized controlled trial included 12 COVID-19. participants were randomly assigned program or without evidence-based ET. Primary outcomes pain reduction improvements functional capacity, measured over 45-week period. secondary outcome was rehabilitation. A kinesiophobia found ET group (P = .048), although no differences observed Barthel index, 6-minute walk test results between groups. Clinically relevant telemedicine group. An effective reducing kinesiophobia, highlighting address aspects However, further needed assess physical

Language: Английский

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Effectiveness of pulmonary rehabilitation programmes and/or respiratory muscle training in patients with post-COVID conditions: a systematic review

Respiratory Research, Journal Year: 2024, Volume and Issue: 25(1)

Published: June 19, 2024

Abstract Background The term “post-COVID-19 condition” refers to the symptomatology that appears between four twelve weeks after Covid-19 infection. These symptoms can persist for or even months, significantly diminishing quality of life affected individuals. primary objective this study was assess effectiveness pulmonary rehabilitation programs and/or respiratory muscle training on sequelae in patients with post-COVID condition. Methods literature search conducted following databases: PubMed, PEDro, Embase, Cochrane, Scopus, and Web Science. Randomized clinical trials were included which participants aged 18 years older. Articles excluded if at least one therapies did not involve training, COVID positive, studies lacked results, finally, interventions without supervision home. This review only encompasses supervised non-virtual interventions. adheres PRISMA statement has been registered PROSPERO database (CRD42023433843). Results outcomes obtained are assessed across variables: Exercise capacity using 6-minute walk test, Dyspnea, fatigue, Pulmonary function, Maximum inspiratory pressure, Quality life. Conclusion Despite absence a specific treatment present, it evident from well-structured program incorporates both aerobic muscular strength exercises along techniques most effective form treatment.

Language: Английский

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Effect of a Virtual Reality Exercise on Patients Undergoing Haemodialysis: A Randomised Controlled Clinical Trial Research Protocol

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(5), P. 4116 - 4116

Published: Feb. 25, 2023

High levels of inflammatory markers have been associated with a greater deterioration renal function and cardiovascular morbidity mortality. For its part, physical exercise has shown to be beneficial in improving the functional, psychological, states patients chronic kidney failure (CKF) undergoing haemodialysis (HD) treatment, their health-related quality life. In recent years, virtual reality (VR) studied described as an effective safe tool that improves patients’ adherence programs. these reasons, we propose analyse effect VR on HD, well exercise, compare them static pedalling exercises. We will randomise 80 CKF into two blind groups: experimental group, which carry out intradialytic program non-immersive (n = 40), control pedal 40). Functional capacity, phycological status, analysed. Higher are expected effects functional capacity psychological status.

Language: Английский

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