Hypothalamic–pituitary–adrenal axis in anorexia nervosa; an underestimated endocrine dysfunction among adolescents DOI Creative Commons
Valeria Calcaterra,

Vittoria Carlotta Magenes,

Nadia Fratangeli

et al.

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 12, 2024

In patients affected by anorexia nervosa (AN) different endocrine abnormalities have been described, but, among them, hypothalamic–pituitary–adrenal (HPA) dysfunction, although associated to important side effects, is underestimated and has no therapeutical options. We present a narrative literature review investigate the HPA axis in with AN, order highlight dysfunction its effects. also described crucial role of monitoring, consider eventual therapeutic preventive strategies AN patients. The now available demonstrates that women girls suffering from higher measures cortisol lower levels androgens as compared controls. These endocrinological disturbances deleterious effects on subjects, both physical psychological point view. It's fundamental for physicians these aspects when assessing mechanisms behind adrenocortical dysfunctions eating disorders remain an open question there are treatments, thus research this issue would be extremely useful highly necessary, especially pediatric field.

Language: Английский

GLP-1 receptor agonists: A novel pharmacotherapy for binge eating (Binge eating disorder and bulimia nervosa)? A systematic review DOI Creative Commons
Laurence Aoun,

Shaza Almardini,

Fares Saliba

et al.

Journal of Clinical & Translational Endocrinology, Journal Year: 2024, Volume and Issue: 35, P. 100333 - 100333

Published: Feb. 29, 2024

Systematically review evidence on using GLP-1RAs for reducing BEB in BED and BN. Comprehensive literature search (PubMed Google Scholar) conducted studies evaluating GLP-1Ras BEB. Extracted data study characteristics, efficacy, safety. Studies show that (liraglutide dulaglutide) reduce BE frequency comorbidities addition to favorable psychiatric side effect profile compared current options. However, large-scale, blinded placebo-controlled trials are lacking. Early findings suggest promising effects of rigorous clinical needed firmly establish dosing, safety, comparative effectiveness before considering a viable novel approach.

Language: Английский

Citations

15
The brainstem reticular formation pivots abnormal neural transmission in the course of Anorexia Nervosa DOI
Gloria Lazzeri, Carla L. Busceti,

A Polzella

et al.

Journal of Neural Transmission, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 24, 2025

Language: Английский

Citations

1
Glucagon-Like Peptide 1 Receptor Agonists in Psychiatry DOI
Hubertus Himmerich, Susan L. McElroy

Journal of Clinical Psychopharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: April 18, 2024

From the 1Centre for Research in Eating and Weight Disorders (CREW), Department of Psychological Medicine, Institute Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom 2South London Maudsley NHS Foundation Trust, 3Lindner Center HOPE, Mason, OH 4Department Psychiatry Behavioral University Cincinnati Cincinnati, OH. Received February 13, 2024; accepted after revision 24, 2024. Address correspondence to: Hubertus Himmerich, MD, Centre SE5 8AF (e-mail: [email protected]).

Language: Английский

Citations

6
The Impact of Chronic Stress Related to COVID-19 on Eating Behaviors and the Risk of Obesity in Children and Adolescents DOI Open Access
Iwona Piątkowska‐Chmiel, Paulina Krawiec, Karolina Ziętara

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 16(1), P. 54 - 54

Published: Dec. 23, 2023

During the COVID-19 pandemic, an increase in incidence of overweight and obesity children was observed. It appears that unhealthy food choices, unbalanced diet, a sedentary lifestyle, as well experiencing stress related to may be contributing this disturbing trend. Chronic is significant factor eating disorders youngsters, involving medical, molecular, psychological elements. Individuals under chronic often focus on appearance weight, leading negative body image disrupted relationships with food, resulting behaviors. also impacts hormonal balance, reducing satiety hormone leptin elevating appetite-stimulating ghrelin, fostering increased hunger uncontrolled snacking. Two systems, hypothalamic–pituitary–adrenal axis sympathetic system adrenal medulla, are activated response stress, causing impaired secretion noradrenaline cortisol. Stress-related mechanisms encompass oxidative neuroinflammation, insulin resistance, neurohormonal neurotransmission disorders. Stress induces risk by disrupting blood sugar regulation fat storage. affects gut microbiome, potentially influencing inflammation metabolic processes linked obesity. In conclusion, multifaceted for children, necessitating comprehensive understanding effective preventive intervention strategies amid escalating prevalence childhood

Language: Английский

Citations

11
The cost of the perfect body: influence mechanism of internalization of media appearance ideals on eating disorder tendencies in adolescents DOI Creative Commons

Xiaoyan Bi,

Qian Liang,

Guangyan Jiang

et al.

BMC Psychology, Journal Year: 2024, Volume and Issue: 12(1)

Published: March 12, 2024

Abstract Background Some studies have examined the relationship between internalization of media appearance ideals and eating disorders. However, few discussed disorder tendencies. To fill this research gap, study was to explore influencing mechanisms on adolescents’ tendencies in Chinese cultural context. Method The Sociocultural Attitudes Towards Appearance Questionnaire, Eating Attitude Test-26, Physical Self-Description Body Image Depression Questionnaire Multidimensional Scale Perceived Social Support were employed investigate 1523 adolescents. collected data analyzed using SPSS 26.0 AMOS 24.0. Result results showed that: (1) had a significant positive predictive effect tendencies; (2) significantly influenced through mediating role body esteem image disturbance respectively, also chain both; (3) social support played moderating tendency. Conclusion Our findings suggest distinct pathways which may influence It is suggested that reducing enhancing can help

Language: Английский

Citations

4
Disordered eating behaviors among a sample of final-year medical students at Cairo University and its relationship with alexithymia and social cognition DOI Creative Commons

Esraa S. Elsherif,

Mona Y. Al-Rakhawy,

Heba Fathy

et al.

Middle East Current Psychiatry, Journal Year: 2025, Volume and Issue: 32(1)

Published: Jan. 14, 2025

Abstract Background This study aims to estimate the risk of eating disorders and their related factors among final-year medical students. Additionally, present is assessing disordered behaviors relationship with alexithymia social cognition. Methods An approved descriptive cross-sectional was carried out at Cairo University’s Faculty Medicine from August 2021 December 2022. The participants were categorized into two distinct groups: Group A (students for disorders) B not disorders). All evaluated using Eating Attitude Test-26 (EAT-26), Disorder Examination Questionnaire (EDE-Q), Toronto Alexithymia Scale (TAS-20), Emotion Identification Test Ekman Program, Reading Mind in Eyes Test-revised version (RMET). Results total 370 students, both male female, participated study. included 136 students (37%), while consisted 234 (63%). Female exhibited a greater developing an disorder ( p = < 0.001). Students classified as displayed significantly elevated scores diminished cognition when compared counterparts without Conclusion Medical are more susceptible eating-related problems. Deficits potentiate disorders.

Language: Английский

Citations

0
Percepción corporal y trastorno del comportamiento alimentario en universitarios españoles DOI Creative Commons
Alberto Domingo Cabo, Andrea Álvarez Rodríguez,

Gabriela Carmona

et al.

Nutrición clínica y dietética hospitalaria/Nutrición clínica, dietética hospitalaria, Journal Year: 2025, Volume and Issue: 45(1)

Published: Feb. 21, 2025

Introducción: El vínculo entre la alimentación y percepción corporal está influenciado por factores biológicos, psicológicos socioculturales, pudiendo desembocar en hábitos peligrosos para salud. Esto se potencia presión social, especialmente dirigida a las mujeres, mantener un cuerpo delgado. Además, etapa de universidad es una crítica que puede propiciar mayor riesgo el desarrollo los trastornos del comportamiento alimentario (TCA) Objetivos: Evaluar asociación condición nutricional, imagen satisfacción con misma, desarrollar TCA muestra jóvenes universitarios ambos sexos. Material métodos: Se ha realizado encuesta 468 estudiantes través Google Forms compuesta test siluetas cuestionario diagnosticar (EAT-26). Resultados: Un 61,5 % hombres 66,8 mujeres encuentra categoría nutricional normopeso. 11,4 5,6 presentan alto TCA. Discusión: estudio diferencias sexos, así como probabilidad TCA, estando estos resultados alienados parte investigaciones revisiones precedentes. Conclusiones: más frecuente sobrepeso obesidad varones insuficiencia ponderal. La figura no asocia manera significativa mientras resulta determinante, ya proporción individuos bajo superior desearían ser delgados, respecto quisieran corpulentos.

Citations

0
Therapie von Essstörungen DOI

Marie-Christin Kevekordes,

Dorothea Portius

Ernährung & Medizin, Journal Year: 2025, Volume and Issue: 40(01), P. 14 - 18

Published: March 1, 2025

Citations

0
Still waiting: Referral patterns, delays, and key factors in accessing specialized eating disorder treatment in an italian cohort DOI Creative Commons
Silvia Tempia Valenta,

F. Marcolini,

Miriam Scalise

et al.

Eating Behaviors, Journal Year: 2025, Volume and Issue: unknown, P. 101968 - 101968

Published: March 1, 2025

Language: Английский

Citations

0
A Cross-sectional Approach in Unveiling the Prevalence, Anthropometric Measurements, and Risk Factors of Eating Disorders among Bengalee Adolescent Females DOI Creative Commons
Shaonee Saha, Reetapa Biswas

Anthropological Review, Journal Year: 2025, Volume and Issue: 88(1), P. 13 - 31

Published: April 2, 2025

Background: The crucial adolescent period demands greater nutritional needs along with physical maturity where overweight can lead to sensitivity towards body image. Excessive appearance concern results in faulty eating habits and complementary behavioral approaches known as disorders (ED). Aim: Due inconsistencies prior information regarding ED on Bengalee females, the cross-sectional study was conducted school females of rural urban areas North 24 Parganas district insights prevalence, anthropometric parameters risk factors ED. Method: design consisted self-reported surveys using standardized questionnaires (Eating disorder examination questionnaire-28; Body shape questionnaire-34) determine ED, dissatisfaction (BD), meal skipping (MS) objective assessments 396 students aged 13–19 years. Statistical analysis interpret findings. Result: 14.39% 44.95% BD cases were found this community significantly high BMI-for-age (BAZ), hip circumference subscale values questionnaire among participants. After chi-square binary logistic regression regular MS be strongest predictor accounting for 14% likelihood followed by fear-of-weight-gain (4.48%) excessive exercise (3.88%). Conclusion: findings highlight a complex interplay psychological social contributing Regular emerged reflecting an unhealthy coping strategy driven stressors such fear weight gain, BD. Influence cultural norms image cannot avoided. Our will help healthcare practitioners designing identification treatment procedures diet plans holistic way during further investigation

Language: Английский

Citations

0