Acta Medica Nicomedia,
Journal Year:
2025,
Volume and Issue:
8(1), P. 45 - 51
Published: Feb. 28, 2025
Objective:
The
COVID-19
pandemic,
caused
by
SARS-CoV-2,
disrupted
global
healthcare
systems
and
significantly
influenced
cardiovascular
health.
This
study
examines
the
temporal
trends
of
acute
coronary
syndromes
(ACS),
including
ST-elevation
myocardial
infarction
(STEMI),
non-ST-elevation
(NSTEMI),
unstable
angina
pectoris
(USAP),
across
pre-pandemic,
post-pandemic
periods.
Methods:
retrospective
observational
was
conducted
at
a
single
tertiary
center
involving
patients
diagnosed
with
ACS
from
January
2018
to
June
2024.
Patients
were
stratified
into
three
cohorts:
pre-pandemic
(January
2018-February
2020),
pandemic
(March
2020-April
2022),
(May
2022-June
2024).
Results:
incidence
STEMI
NSTEMI
increased
in
period
compared
those
other
periods
(p
Cureus,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 14, 2025
Background
The
COVID-19
pandemic
has
highlighted
the
enduring
health
burden
of
long
COVID,
scientifically
termed
postacute
sequelae
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection
or
PASC.
Long
COVID
manifests
as
diverse
symptoms
affecting
multiple
organ
systems,
significantly
impacting
individuals
globally,
and
especially
underrepresented
rural
populations.
Objective
This
study
aimed
to
evaluate
prevalence
chronic
fatigue
(CFS)
among
laboratory-confirmed
patients
in
India,
focusing
on
identifying
its
predictors
implications
for
healthcare
systems
resource-limited
settings.
Methodology
Retrospective
data
analysis
was
conducted
follow-up
visits
post-COVID-19
field
practice
area
AIIMS
Mangalagiri,
Nuthakki,
Andhra
Pradesh,
India.
involved
500
survivors
diagnosed
via
reverse
transcription
polymerase
chain
reaction
(RT-PCR)
between
2023
2024.
Data
collected
a
semi-structured
questionnaire
retrieve
socio-demographic
clinical
parameters,
while
CFS
severity
assessed
using
validated
scoring
system.
Multivariable
logistic
regression
path
were
used
examine
associations
CFS.
Results
seen
107
(21.4%;
95%
CI:
18.01-25.22).
Risk
factors
included
older
age
(adjusted
odds
ratio
aOR:
15.90
≥60
years),
female
gender
(aOR:
1.90),
comorbidities
3.92).
Common
observed
180
(36%),
joint
pain
185
(37%),
muscle
182
(36.4%)
patients.
There
no
significant
association
vaccination
Conclusion
underscores
substantial
post-COVID
populations,
with
patients,
adults,
those
being
at
greater
risk.
Tailored
interventions
proactive
monitoring
are
critical
address
this
challenge.
Future
research
should
explore
underlying
mechanisms
assess
role
mitigating
sequelae.
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(4), P. e0320643 - e0320643
Published: April 11, 2025
Introduction
According
to
WHO
long
COVID
is
defined
as
a
continuation
or
development
of
new
symptoms
3
months
after
the
initial
SARS-CoV-2
infection,
with
these
lasting
for
at
least
2
no
other
explanation.
We
followed
up
patients
an
episode
acute
COVID-19
1
year
hospital
discharge
from
different
parts
India.
Methods
This
was
multi-centric
study
among
≥18
years
hospitalized
COVID-19,
which
recruited
6
weeks
(baseline).
Quantitative
data
on
demographics,
pre-existing
co-morbidities,
risk
factors,
signs
and
parameters
during
infection
were
noted
baseline.
They
collected
telephonically
thereafter
3–6,
6–9
9–12
regarding
self-reported
persistence
symptoms.
A
qualitative
component
included
face
in-depth
interviews
elicit
information
perceived
health
problems,
quality
life
financial
burden
due
COVID-19.
Results
total
315
enrolled,
majority
being
males
(59.4%).
The
median
age
52
(IQR
40,
63).
prevalence
16.5%.
At
12
months,
35.2%
25.9%
patients,
reported
more
than
one
symptom
that
affected
their
life.
Shortness
breath
common
each
time
point,
persistent
muscle
pain
weakness
waxed
waned.
Variables
post
(baseline)
such
shortness
(OR
2.22
CI
1.06–4.65,
p
=
<0.05),
cough
6.93,
2.36–20.30,
fatigue
2.34,
1.05–5.23,
weight
loss
2.90,
1.30–6.49,
<0.05)
significantly
associated
COVID.
Conclusion
found
in
16.5%
who
self
non
–
recovery
year.
Physical
symptoms,
mental
issues
mobility
significant
number
following
infection.
In
urgently
need
therapeutic
interventions
can
improve
patients.
World Journal of Gastroenterology,
Journal Year:
2024,
Volume and Issue:
30(37), P. 4104 - 4114
Published: Sept. 26, 2024
Since
the
beginning
of
coronavirus
disease
(COVID)
2019
pandemic,
thousands
articles
on
topic
have
been
published,
and
although
there
is
a
growing
trend
research
another
associated
condition,
long
disease,
important
points
still
remain
to
be
clarified
in
this
respect.
Robust
evidence
has
suggested
relevant
link
between
new
clinical
discoveries
molecular
mechanisms
that
could
with
manifestations
different
signs
symptoms
involving
cases
COVID.
However,
one
existing
gaps
requires
further
investigation
concerns
possible
relationship
gut
candidiasis
While
recent
studies
also
suggest
an
interplay
occurrence
these
two
conditions,
it
not
yet
fully
clear
how
may
happen,
as
well
specifics
regarding
pathophysiological
involved.
In
connection
advent
potential
strengthening
body
supporting
hypothesis
COVID,
better
understanding
presentation,
pathophysiology
management
such
should
essential
useful
for
both,
additional
advances
towards
more
targeted
appropriate
case
management.
Knowing
about
signs,
symptoms,
complications
COVID
order
effectively
mitigate
related
burden
provide
higher
quality
care
life
affected
population.
light
need
outcomes,
here
we
review
discuss
content
aspects
including
its
condition
candidiasis,
propositions
future
research.
COVID,
Journal Year:
2024,
Volume and Issue:
4(9), P. 1440 - 1462
Published: Sept. 12, 2024
Long
COVID
comprises
persistent
symptoms
that
extend
beyond
four
weeks
post-SARS-CoV-2
infection.
The
potential
association
between
long
and
the
endorsement
of
COVID-19
conspiracy
theories
has
not
been
explored,
particularly
in
Arab
countries,
where
high
these
reported.
This
study
aimed
to
explore
endorsing
prevalence
self-reported
among
adults
Jordan
Kuwait
addition
other
countries.
employed
a
cross-sectional
design
using
Computer-Assisted
Web
Interviewing
(CAWI),
conducted
Arabic.
Recruitment
utilized
convenience-based
snowball
sampling
via
social
media
survey
was
distributed
July
2024.
manifestations
were
assessed
across
ten
recognized
symptoms,
belief
measured
five-point
Likert
scale
five
items.
final
sample
comprised
755
respondents,
majority
whom
history
confirmed
diagnosis
at
least
once
(n
=
493,
65.2%).
results
indicated
neutral
average
attitude
towards
(mean
score
15.18
±
4.64
out
30.00).
Participants
with
scores
more
likely
report
(aOR
6.85,
p
<
0.001)
or
middle
2.82,
0.008)
compared
those
lower
scores.
Additional
predictors
higher
reporting
included
female
sex,
household
income,
frequent
infections,
hospitalizations.
revealed
significant
correlation
frequency
magnitude
symptom
reporting.
findings
also
highlighted
influence
sociodemographic
factors
infection
on
reporting,
which
suggests
public
health
strategies
should
address
mitigate
challenges
effectively.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(23), P. 7124 - 7124
Published: Nov. 25, 2024
Long
COVID-19
(LC)
is
a
poorly
understood,
multifactorial
condition
that
persists
for
at
least
three
months
following
SARS-CoV-2
infection.
The
underlying
pathophysiological
mechanisms
responsible
the
wide
range
of
associated
symptoms-including
fatigue,
brain
fog,
and
respiratory
issues-remain
unclear.
However,
emerging
evidence
suggests
reactivation
latent
viral
infections,
such
as
Epstein-Barr
virus,
cytomegalovirus,
varicella-zoster
may
significantly
contribute
to
complexity
LC.
These
viruses
can
be
reactivated
by
SARS-CoV-2,
contributing
chronic
inflammatory
state
prolongs
symptomatology.
This
review
confirms
potential
involvement
infections
in
LC
examines
whether
these
play
an
independent
role
or
act
synergistically
with
other
factors.
In
addition,
recent
studies
have
highlighted
persistence
immune
dysregulation
key
elements
Our
findings
suggest
preventative
strategies,
including
vaccination
antiviral
treatments
during
acute
phase
COVID-19,
show
reducing
risk
preventing
reactivation.
tailored
diagnostic
therapeutic
strategies
targeting
are
urgently
needed.
Identifying
biomarkers
reactivation,
particularly
high-risk
populations,
could
considered
another
effective
strategy
mitigate
severity.
Further
research
crucial
better
understand
interactions
between
improve
prevention
treatment
Abstract
Introduction:
Long
COVID
(LC)
affects
multiple
systems
and
has
a
significant
health
impact
on
patients
society.
Therefore,
long
services
should
address
patients’
needs
through
holistic
assessment
monitoring
of
symptoms.
Aim:
The
aim
was
to
understand
which
the
symptoms
were
most
least
likely
improve,
after
our
rehabilitation
intervention
so
that
measures
in
clinic
could
be
modified
meet
needs.
At
same
time,
we
wanted
assess
feasibility
using
C19-YRS
ELAROS
application
LC
during
attendance.
Methodology:
In
this
study,
total
50
who
have
attended
Salford,
UK;
assessed
by
digitalised
application.
A
100
eligible
initial
final
post
assessments
analysed.
Conclusion:
Pain
anxiety
two
improve
at
clinic,
whereas
swallowing
difficulty
is
improve.
Issues
with
caring
for
family/
social
life
(symptoms
affecting
role)
are
worsen
even
treatment.
It
feasible
monitor
track
utilising
version
via
App.
This
also
allows
tracking
overtime.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 31, 2024
Abstract
Background
Long
COVID
is
a
multisystem
condition
first
identified
in
the
COVID-19
pandemic
characterised
by
wide
range
of
symptoms
including
fatigue,
breathlessness
and
cognitive
impairment.
Considerable
disagreement
exists
who
most
at
risk
developing
COVID,
driven
part
incomplete
coding
diagnosis
medical
records.
Methods
This
was
retrospective
observational
cohort
study
using
an
integrated
primary
secondary
care
dataset
from
North
West
London,
covering
over
2.7
million
patients.
Patients
with
were
through
clinical
terms
their
record.
Multivariate
logistic
regression
used
to
identify
factors
associated
having
diagnosis,
while
multivariate
quantile
predicting
time
recorded.
Findings
A
total
6078
patients
term
record,
0.33%
registered
adult
population.
Women,
those
aged
41
70
years
or
Asian
ethnicity
more
likely
have
recorded
alongside
pre-existing
anxiety,
asthma,
depressive
disorder
eczema
living
outside
socioeconomically
deprived
areas.
Men,
years,
black
diagnosed
earlier
pandemic,
later.
Interpretation
poorly
coded
records,
significant
differences
exist
between
patient
groups
likelihood
receiving
diagnosis.
long-term
conditions
also
frequent
incidence
new
conditions.
The
experience
provides
crucial
insight
into
inequities
access
timely
for
complex
conditions,
importance
effective
health
informatics
practices
provide
robust,
analytical
support
front-line
services.
Funding
National
Institute
Health
Care
Research
(NIHR)
Ref:
COV-LT2-0016
