International Journal of Nanomedicine,
Journal Year:
2023,
Volume and Issue:
Volume 18, P. 3973 - 3988
Published: July 1, 2023
Abstract:
Pancreatic
cancer
is
a
highly
malignant
and
incurable
disease,
characterized
by
its
aggressive
nature
high
fatality
rate.
The
most
common
type
pancreatic
ductal
adenocarcinoma
(PDAC),
which
has
poor
prognosis
mortality
Current
treatments
for
mainly
encompass
surgery,
chemotherapy,
radiotherapy,
targeted
therapy,
combination
regimens.
However,
despite
efforts
to
improve
prognosis,
the
5-year
survival
rate
remains
very
low.
Therefore,
it's
urgent
explore
novel
therapeutic
approaches.
With
rapid
development
of
strategies
in
recent
years,
new
ideas
have
been
provided
treating
cancer.
This
review
expositions
advancements
nano
drug
delivery
system,
molecular
drugs,
photo-thermal
treatment
combined
with
nanotechnology
It
comprehensively
analyzes
prospects
cancer,
aiming
at
deeper
understanding
existing
drugs
approaches,
promoting
attempting
enhance
effect
patients
this
disease.
Keywords:
ChemSusChem,
Journal Year:
2019,
Volume and Issue:
12(10), P. 2039 - 2054
Published: April 1, 2019
To
liberate
society
from
its
dependence
on
fossil-based
fuels
and
materials
it
is
pivotal
to
explore
components
of
renewable
plant
biomass
in
applications
that
benefit
their
intrinsic
biodegradability,
safety,
sustainability.
Lignin,
a
byproduct
the
pulp
paper
industry,
plausible
material
for
carrying
various
types
cargo
small-
large-scale
applications.
Herein,
possibilities
constraints
regarding
physical-chemical
properties
lignin
source
as
well
modifications
processing
required
render
lignins
suitable
loading
release
pesticides,
pharmaceuticals,
biological
macromolecules
reviewed.
In
addition,
technical
challenges,
regulatory
toxicological
aspects,
future
research
needed
realize
some
promises
nano-
microscaled
hold
sustainable
are
critically
discussed.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
23(11), P. 3790 - 3817
Published: Jan. 1, 2021
This
review
summarizes
the
recent
advances
in
fabrication
strategies
and
versatile
applications
of
lignin-derived
biodegradable
film
materials
from
viewpoint
sustainable
development.
Frontiers in Energy Research,
Journal Year:
2022,
Volume and Issue:
9
Published: Jan. 11, 2022
Lignin
is
identified
as
a
promising
candidate
in
renewable
energy
and
bioproduct
manufacturing
due
to
its
high
abundance,
polymeric
structure,
biochemical
properties
of
monomers.
Thus,
emerging
opportunities
exist
generating
high-value
small
molecules
from
lignin
through
depolymerization.
This
review
aims
at
providing
an
overview
the
major
technologies
The
feasibility
large-scale
implementation
these
technologies,
including
thermal,
biological,
chemical
depolymerizations,
are
discussed
relation
potential
industrial
applications.
alternative
petroleum-based
chemicals
has
been
well
documented.
attempts
emphasize
applications
lignin-derived
monomers
their
derivatives
bioactives
food,
natural
health
product,
pharmaceutical
sectors.
critical
prospects
challenges
bioproducts
reveals
that
advancement
research
development
required
explore
depolymerization
lignins
full
potential.
Nanomaterials,
Journal Year:
2021,
Volume and Issue:
11(5), P. 1336 - 1336
Published: May 19, 2021
Lignin
nanomaterials
have
emerged
as
a
promising
alternative
to
fossil-based
chemicals
and
products
for
some
potential
added-value
applications,
which
benefits
from
their
structural
diversity
biodegradability.
This
review
elucidates
perspective
in
recent
research
on
nanolignins
nanocomposites.
It
summarizes
the
different
nanolignin
preparation
methods,
emphasizing
anti-solvent
precipitation,
self-assembly
interfacial
crosslinking.
Also
described
are
of
various
nanocomposites
by
chemical
modification
compounds
with
inorganic
materials
or
polymers.
Additionally,
advances
numerous
high-value
such
use
food
packaging,
biomedical,
engineering
biorefineries,
described.
Antioxidants,
Journal Year:
2021,
Volume and Issue:
10(2), P. 274 - 274
Published: Feb. 10, 2021
Green,
biocompatible,
and
biodegradable
antioxidants
represent
a
milestone
in
cosmetic
cosmeceutical
applications.
Lignin
is
the
most
abundant
polyphenol
nature,
recovered
as
low-cost
waste
from
pulp
paper
industry
biorefinery.
This
polymer
characterized
by
beneficial
physical
chemical
properties
which
are
improved
at
nanoscale
level
due
to
emergence
of
antioxidant
UV
shielding
activities.
Here
we
review
use
lignin
nanoparticles
applications,
focusing
on
sunscreen
antiaging
formulations.
Advances
technology
for
preparation
described
highlighting
structure
activity
relationships.
Materials Today Chemistry,
Journal Year:
2022,
Volume and Issue:
26, P. 101198 - 101198
Published: Sept. 29, 2022
Spherical
particles
based
on
materials
of
natural
origin
have
recently
gained
increased
attention
because
their
unique
properties,
including
shape,
structure,
and
ability
to
combine
with
other
materials.
Lignin
has
potential
be
applied
across
multiple
sectors,
recent
focus
its
valorization
in
high
end
application
routes
which
favor
renewability,
biocompatibility,
non-toxicity.
The
most
promising
findings
are
reported,
that
spherical
lignin
a
very
effective
carrier
delivery
vehicle
for
active
pharmaceutical
ingredients
the
treatment
various
diseases,
cancers
etc.
Due
developments,
can
successfully
used
accelerated
wound
healing
growth
inhibition
against
variety
bacterial
strains
taking
advantage
inherent
antimicrobial
antioxidant
properties.
Notably,
also
finding
opportunities
agrochemical
industry,
combination
properties
such
as
stability,
composability,
possibility
encapsulation
pesticides
fungicides
without
pollution
environment.
presented
review
aims
discuss
impact
developments
related
lignin-based
novel
biomedical
biotechnological
application,
may
provide
guidance
future
possibilities
lignin.
