World Journal of Biology Pharmacy and Health Sciences,
Journal Year:
2024,
Volume and Issue:
17(2), P. 253 - 296
Published: Feb. 20, 2024
This
litrature
review
paper
highlights
the
role
of
phytocannabinoids
in
controlling
cervical
cancer.
Cervical
cancer
is
one
leading
causes
death
among
females
worldwide.
(CC)
a
malignant
form
tumor
which
originates
cervix.
cancer,
develops
woman’s
cervix,
second-most
common
women
India
The
causative
agent
persistent
infection
with
high-risk
subtypes
Human
Papillomavirus
(HPV)
and
E5,
E6
E7
viral
onco-proteins
cooperate
host
factors
to
induce
maintain
phenotype.
papillomavirus
responsible
for
subclinical/clinical
lesions
HPV
types
16
18
are
most
identified
invasive
Currently,
recommended
therapeutic
regimens
include
chemotherapy,
radiation
therapy
either
alone
or
combination
surgical
interventions.
However,
they
present
several
limitations
including
side
effects
ineffectiveness.
Medicinal
plants
Cannabis
sativa
have
been
used
decades
health
benefits
treat
different
diseases
has
thousands
years
recreational,
medicinal,
religious
purposes.
Phytocannabinoids
cannabinoids
that
occur
naturally
cannabis
plant.
two
well
known
their
properties
are,
Δ9-tetrahydrocannabinol
(THC)
Cannabidiol
(CBD).
hold
big
promise
therapy.
there
need
understand
more
about
Endocannabinoid
system
(ECS)
normal
human
physiology
transformations.
Molecular
mechanisms
regulation
anticancer
also
be
clarified.
treatment
durations
existing
trials
concern.
Future
epidemiological
clinical
studies
required
further
assess
herbal
medicines
prevention
In
addition,
preclinical
trial
evaluations
not
specifically
conducted,
so
investigations
related
this
warranted.
Therefore,
immunization
programme
best
ideal
solution
eradication
Frontiers in Chemistry,
Journal Year:
2023,
Volume and Issue:
11
Published: Oct. 19, 2023
Introduction:
Three
different
shapes
of
gold
nanoparticles
were
synthesized
in
this
experiment.
At
the
same
time,
studies
compared
their
effects
with
human
serum
albumin
(HSA).
Methods:
Gold
(AuNPs)
three
morphologies,
such
as,
nanospheres
(AuNSs),
nanorods
(AuNRs),
and
nanoflowers
(AuNFs)
via
a
seeding
method
characteristic
absorption
peaks
detected
using
ultraviolet-visible
(UV-vis)
spectroscopy,
Telectron
microscopy
(TEM),
Dynamic
Light
Scattering
(DLS)
Zeta
potential
measurements,
circular
dichroism
(CD),
Fourier
transform
infrared
spectroscopy
(FTIR)
to
study
interactions
between
them
HSA.
By
comparing
thermodynamic
parameters
quenching
mechanism
materials,
similarities
differences
determined
Results:
The
results
showed
that
an
increase
concentration
AuNPs
UV-vis
peak
intensity
mixed
solution
increased,
but
its
fluorescence
was
quenched.
This
indicates
types
interact
HSA,
represent
static
process,
which
is
consistent
conclusions
derived
from
three-dimensional
experiments.
Through
variable-temperature
experiments,
binding
constants,
number
sites,
HSA
determined.
Gibbs
free
energy
changes
<0,
indicating
reactions
are
spontaneous,
resulting
associated
matter.
Binding
constant
measurements
indicated
strongest
took
place
AuNFs
In
addition,
fluorescence,
CD
FTIR
can
induce
conformational
reduce
α-helix
content.
Among
them,
have
smallest
ability
changes.
Discussion:
According
studies,
more
favorably
be
used
as
reference
for
administration
drugs
containing
AuNPs.
World Journal of Biology Pharmacy and Health Sciences,
Journal Year:
2024,
Volume and Issue:
17(2), P. 253 - 296
Published: Feb. 20, 2024
This
litrature
review
paper
highlights
the
role
of
phytocannabinoids
in
controlling
cervical
cancer.
Cervical
cancer
is
one
leading
causes
death
among
females
worldwide.
(CC)
a
malignant
form
tumor
which
originates
cervix.
cancer,
develops
woman’s
cervix,
second-most
common
women
India
The
causative
agent
persistent
infection
with
high-risk
subtypes
Human
Papillomavirus
(HPV)
and
E5,
E6
E7
viral
onco-proteins
cooperate
host
factors
to
induce
maintain
phenotype.
papillomavirus
responsible
for
subclinical/clinical
lesions
HPV
types
16
18
are
most
identified
invasive
Currently,
recommended
therapeutic
regimens
include
chemotherapy,
radiation
therapy
either
alone
or
combination
surgical
interventions.
However,
they
present
several
limitations
including
side
effects
ineffectiveness.
Medicinal
plants
Cannabis
sativa
have
been
used
decades
health
benefits
treat
different
diseases
has
thousands
years
recreational,
medicinal,
religious
purposes.
Phytocannabinoids
cannabinoids
that
occur
naturally
cannabis
plant.
two
well
known
their
properties
are,
Δ9-tetrahydrocannabinol
(THC)
Cannabidiol
(CBD).
hold
big
promise
therapy.
there
need
understand
more
about
Endocannabinoid
system
(ECS)
normal
human
physiology
transformations.
Molecular
mechanisms
regulation
anticancer
also
be
clarified.
treatment
durations
existing
trials
concern.
Future
epidemiological
clinical
studies
required
further
assess
herbal
medicines
prevention
In
addition,
preclinical
trial
evaluations
not
specifically
conducted,
so
investigations
related
this
warranted.
Therefore,
immunization
programme
best
ideal
solution
eradication
