Applied Food Research,
Journal Year:
2023,
Volume and Issue:
3(1), P. 100283 - 100283
Published: March 5, 2023
Cloves,
a
commonly
used
spice,
are
significant
source
of
bioactive
compounds
such
as
flavonoids,
hydroxybenzoic
acids,
hydroxycinnamic
and
others.
The
major
phenolic
constituents
in
cloves
eugenol,
eugenyl
acetate,
caryophyllene,
which
contribute
to
their
high
antioxidant
activity.
activity
can
confer
protection
the
human
body
against
free
radicals
chronic
diseases.
In
addition,
able
increase
shelf
life
food
products
by
hindering
lipid
peroxidation,
frequently
occurs
during
processing
storage.
Cloves
were
also
found
exhibit
bactericidal
activity,
makes
them
suitable
candidate
for
application
preservation.
This
review
covers
phytochemical
activities
cloves,
antimicrobial
These
crucial
development
functional
additives
packaging
materials
model
systems,
could
potentially
satisfy
growing
needs
consumers
nutritional
safety
aspects
food.
Molecules,
Journal Year:
2021,
Volume and Issue:
26(23), P. 7407 - 7407
Published: Dec. 6, 2021
Conventional
cancer
treatments
have
shown
several
unfavourable
adverse
effects,
as
well
an
increase
in
anticancer
drug
resistance,
which
worsens
the
impending
therapy.
Thus,
emphasis
is
currently
en
route
for
natural
products.
There
great
interest
bioactive
components
from
medicinal
plants
possessing
characteristics.
For
example,
clove
(Syzygium
aromaticum
L.)
(Family
Myrtaceae)
a
highly
prized
spice
that
has
been
historically
utilized
food
preservative
and
diverse
medical
uses.
It
reckoned
amongst
valued
sources
of
phenolics.
indigenous
to
Indonesia
but
cultivated
various
places
world.
Among
active
components,
eugenol,
principal
component
S.
aromaticum,
optimistic
properties
comprising
antioxidant,
anti-inflammatory,
actions.
Eugenol
(4-allyl-2-methoxyphenol)
musky
oil
mainly
obtained
clove.
long
all
over
world
result
its
broad
like
anticancer,
antimicrobial
activities.
continues
pique
investigators’
because
multidirectional
activities,
suggests
it
could
be
used
medications
treat
different
ailments.
Anticancer
effects
eugenol
are
accomplished
by
mechanisms
inducing
cell
death,
cycle
arrest,
inhibition
migration,
metastasis,
angiogenesis
on
lines.
Besides,
might
adjunct
remedy
patients
who
treated
with
conventional
chemotherapy.
This
combination
leads
boosted
effectiveness
decreased
toxicity.
The
present
review
focuses
types
their
possible
mechanisms.
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(4), P. 488 - 488
Published: April 19, 2024
Plants
have
proven
to
be
important
sources
for
discovering
new
compounds
that
are
useful
in
the
treatment
of
various
diseases
due
their
phytoconstituents.
Clove
(
European journal of medical research,
Journal Year:
2025,
Volume and Issue:
30(1)
Published: Jan. 7, 2025
Diabetic
foot
infections
(DFIs)
are
a
significant
complication
in
diabetes
mellitus,
leading
to
increased
morbidity,
hospitalizations,
and
healthcare
burdens.
The
growing
prevalence
of
antibiotic-resistant
pathogens
has
reduced
the
efficacy
conventional
treatments,
highlighting
need
for
alternative
therapeutic
strategies.
Natural
products,
known
their
antimicrobial,
anti-inflammatory,
wound-healing
properties,
have
garnered
attention
as
potential
treatments
DFIs.
This
review
examines
key
natural
compounds,
including
eugenol,
thymol,
carvacrol,
curcumin,
Aloe
vera,
mechanisms
action
combating
diabetic
infections.
We
analyze
antimicrobial
these
ability
inhibit
biofilm
formation,
role
wound
healing.
also
explores
challenges
integrating
products
into
clinical
practice
use
alongside
or
place
traditional
antibiotic
therapies.
Our
findings
suggest
that
could
play
crucial
developing
sustainable
effective
treatment
strategies
DFIs,
especially
face
rising
resistance.
ACS Omega,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 27, 2025
Decreasing
fossil
fuel
resources
results
in
a
growing
demand
for
polymeric
materials
obtained
from
renewable
raw
materials,
such
as
eugenol.
Therefore,
this
work
aimed
to
assess
the
kinetics
of
cross-linking
and
degradation
epoxy
resin
eugenol
derivatives
cured
with
three
types
amines:
aliphatic:
triethylenetetramine
(TETA);
aromatic:
diaminodiphenylmethane
(DDM),
cycloaliphatic
isophorone
diamine
(IDA).
The
product
was
characterized
by
1H,
13C,
31P
NMR
well
ESI
MS
techniques.
curing
biobased
studied
using
differential
scanning
calorimetry
(DSC)
at
different
heating
rates.
Fourier
transform
infrared
(FTIR)
spectroscopy
used
chemical
changes
bioepoxy
monomer
after
process.
DSC
method
confirmed
occurrence
an
exothermic
reaction
tested
bioresin
all
agents.
peak
temperature
Tp
enthalpy
ΔH
values
determined
during
analysis
depended
on
type
agent.
highest
(142.6–161.4
°C)
(28.5–38.3
J/g)
were
recorded
TEEP
+
DDM
composition.
For
remaining
compositions,
lower
follows:
TETA,
=
115.0
129.9
°C
12.4–26.5
J/g
IDA,
118.0–137.1
16.3
35.5
J/g.
According
Kissinger
Ozawa
model,
activation
energy
process
determined.
calculated
energies
according
65.38
55.90
kJ/mol
60.09
63.84
DDM,
57.36
60.85
TEEP+IDA,
respectively.
thermal
eugenol-based
thermogravimetric
(TGA)
nitrogen
atmosphere.
Moreover,
it
should
be
emphasized
that
compared
commercial
resins,
has
much
maximum
rate
DTG
higher
amount
char
residue
degradation,
both
air.
Frontiers in Nutrition,
Journal Year:
2022,
Volume and Issue:
9
Published: Sept. 15, 2022
Many
studies
have
demonstrated
the
use
of
synthetic
preservatives
and
chemical
additives
in
food
is
causing
poisoning,
cancer,
other
degenerative
disorders.
New
solutions
for
preservation
with
quality
maintenance
are
currently
emerging.
As
a
result,
public
concern
has
grown,
as
they
desire
to
eat
healthier
products
that
natural
compounds
rather
than
ones.
Clove
highly
prized
spice
used
preservative
variety
therapeutic
reasons.
essential
oil
its
principal
active
component,
eugenol,
indicate
antibacterial
antifungal
action,
aromaticity,
safety
promising
valuable
antiseptics
sector.
eugenol
found
strong
inhibition
effects
on
food-source
bacteria,
mechanisms
linked
lowering
migration
adhesion,
well
blocking
creation
biofilm
various
virulence
factors.
This
review
emphasizes
importance
CEO
(clove
oil)
industry
how
it
can
be
explored
edible
coatings
deliver
functional
properties
preservation.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(4), P. 1135 - 1135
Published: April 3, 2023
The
main
factors
that
determine
the
low
effectiveness
of
chemotherapy
are
target
bioavailability
antitumor
drugs
and
efflux
process.
In
attempts
to
overcome
this
problem,
several
approaches
proposed
here.
Firstly,
development
polymeric
micellar
systems
based
on
chitosan
grafted
by
fatty
acids
(different
types
optimize
their
properties),
which,
one
hand,
increase
solubility
cytostatics
and,
other
effectively
interact
with
tumor
cells
due
polycationic
properties
chitosan,
allowing
for
more
effective
penetration
cytostatic
into
cells.
Secondly,
use
adjuvants-synergists
(such
as
eugenol)
included
in
same
formulation-that
selectively
enhance
accumulation
retention
pH-
temperature-sensitive
micelles
developed
show
high
entrapment
efficiency
both
eugenol
(EG)
>60%
release
drug
a
prolonged
manner
40
h
weakly
acidic
medium
corresponding
microenvironment
tumors.
slightly
alkaline
environment,
circulates
longer
(more
than
60
h).
thermal
sensitivity
is
realized
an
molecular
mobility
which
undergoes
phase
transition
at
32-37
°C.
effect
doxorubicin
(Dox)
cancerous
A549
model
healthy
human
embryonic
renal
epithelium
(HEK293T)
was
studied
FTIR
spectroscopy
fluorescence
microscopy.
Micellar
Dox
penetrates
cancer
2-3
times
efficiently
when
using
EG
adjuvant,
inhibits
efflux,
demonstrated
significant
ratio
intra-
extracellular
concentrations
cytostatic.
However,
here
it
worth
remembering
about
they
should
not
be
damaged:
according
changes
spectra,
HEK293T
combination
reduced
20-30%
compared
simple
Thus,
experimental
developments
combined
have
been
treatment
multiple
resistance.
Nature Communications,
Journal Year:
2023,
Volume and Issue:
14(1)
Published: July 24, 2023
Plant-derived
phenylpropanoids,
in
particular
phenylpropenes,
have
diverse
industrial
applications
ranging
from
flavors
and
fragrances
to
polymers
pharmaceuticals.
Heterologous
biosynthesis
of
these
products
has
the
potential
address
low,
seasonally
dependent
yields
hindering
ease
widespread
manufacturing.
However,
previous
efforts
been
hindered
by
inherent
pathway
promiscuity
microbial
toxicity
key
intermediates.
Here,
this
study,
we
establish
propensity
a
tripartite
co-culture
overcome
limitations
demonstrate
our
knowledge
first
reported
de
novo
phenylpropene
production
simple
sugar
starting
materials.
After
initially
designing
system
accumulate
eugenol,
platform
modularity
downstream
enzyme
was
leveraged
quickly
create
avenues
for
hydroxychavicol
chavicol
production.
The
consortia
found
be
compatible
with
Engineered
Living
Material
platforms
that
allow
reusable,
cold-chain-independent
distributed
This
work
lays
foundation
further
deployment
modular
approaches
produce
plant
secondary
metabolites.
