Myco-Synthesized Molluscicidal and Larvicidal Selenium Nanoparticles: A New Strategy to Control Biomphalaria alexandrina Snails and Larvae of Schistosoma mansoni with an In Silico Study on Induced Oxidative Stress DOI Creative Commons
Mostafa Y. Morad, Heba El-Sayed, Ahmed A. Elhenawy

et al.

Journal of Fungi, Journal Year: 2022, Volume and Issue: 8(3), P. 262 - 262

Published: March 4, 2022

Schistosomiasis is a tropical disease with socioeconomic problems. The goal of this study was to determine the influence myco-synthesized nano-selenium (SeNPs) as molluscicide on Biomphlaria alexandrina snails, reducing spread via non-toxic routes. In study, Penicillium chrysogenum culture filtrate metabolites were used reductant for selenium ions form nano-selenium. SeNPs characterized UV-Vis spectrophotometer, Fourier transform infrared (FT-IR) spectroscopy, transmission electron microscopy (TEM), dynamic light scattering (DLS), and X-ray diffraction (XRD). Myco-synthesized had significant molluscicidal effect B. snails after 96 h exposure at concentration 5.96 mg/L. also miracidicidal cercaricidal properties against S. mansoni. Some alterations observed in hemocytes exposed SeNPs, including formation pseudopodia an increasing number granules. Furthermore, lipid peroxide, nitric oxide (NO), malondialdehyde (MDA), glutathione s-transferase (GST) increased significantly dose-dependent manner, while superoxide dismutase (SOD) decreased. comet assay revealed that could cause breaks DNA levels. silico promising antioxidant properties. conclusion, have potential be molluscicides larvicides.

Language: Английский

Antioxidants: Classification, Natural Sources, Activity/Capacity Measurements, and Usefulness for the Synthesis of Nanoparticles DOI Open Access
Jolanta Flieger, Wojciech Flieger, Jacek Baj

et al.

Materials, Journal Year: 2021, Volume and Issue: 14(15), P. 4135 - 4135

Published: July 25, 2021

Natural extracts are the source of many antioxidant substances. They have proven useful not only as supplements preventing diseases caused by oxidative stress and food additives oxidation but also system components for production metallic nanoparticles so-called green synthesis. This is important given drastically increased demand nanomaterials in biomedical fields. The ecological technology producing can be plants or microorganisms (yeast, algae, cyanobacteria, fungi, bacteria). review presents recently published research on synthesis nanoparticles. conditions biosynthesis possible mechanisms nanoparticle formation with participation bacteria presented. potential natural biogenic depends content reducing assessment activity multicomponent mixtures still a challenge analytical chemistry. There no universal test measuring total capacity (TAC). vitro chemical tests that quantify scavenging free radicals their ability to chelate metals reduce radical damage. paper classification antioxidants non-enzymatic methods testing vitro, particular emphasis based Examples recent studies obtained from different species such plants, bacteria, lichens, actinomycetes were collected, giving evaluation methods, reference antioxidants, details preparation extracts.

Language: Английский

Citations

288

The Catalytic Activity of Biosynthesized Magnesium Oxide Nanoparticles (MgO-NPs) for Inhibiting the Growth of Pathogenic Microbes, Tanning Effluent Treatment, and Chromium Ion Removal DOI Open Access
Ebrahim Saied, Ahmed M. Eid, Saad El-Din Hassan

et al.

Catalysts, Journal Year: 2021, Volume and Issue: 11(7), P. 821 - 821

Published: July 6, 2021

Magnesium oxide nanoparticles (MgO-NPs) were synthesized using the fungal strain Aspergillus terreus S1 to overcome disadvantages of chemical and physical methods. The factors affecting biosynthesis process optimized as follows: concentration Mg(NO3)2·6H2O precursor (3 mM), contact time (36 min), pH (8), incubation temperature (35 °C). characterization biosynthesized MgO-NPs was accomplished UV-vis spectroscopy, Fourier transform infrared (FT-IR) transmission electron microscopy (TEM), scanning microscopy—energy dispersive X-ray (SEM-EDX), diffraction (XRD), dynamic light scattering (DLS). Data confirmed successful formation crystallographic, spherical, well-dispersed with a size range 8.0–38.0 nm at maximum surface plasmon resonance 280 nm. biological activities including antimicrobial activity, biotreatment tanning effluent, chromium ion removal investigated. highest growth inhibition pathogenic Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Candida albicans achieved 200 μg mL–1 MgO-NPs. exhibited high efficacy decolorize effluent (96.8 ± 1.7% after 150 min 1.0 µg mL–1) greatly decrease parameters total suspended solids (TSS), dissolved (TDS), oxygen demand (BOD), (COD), conductivity percentages 98.04, 98.3, 89.1, 97.2, 97.7%, respectively. Further, showed strong potential remove ions from 835.3 mg L–1 21.0 L–1, percentage 97.5%.

Language: Английский

Citations

126

Enhanced Antimicrobial, Cytotoxicity, Larvicidal, and Repellence Activities of Brown Algae, Cystoseira crinita-Mediated Green Synthesis of Magnesium Oxide Nanoparticles DOI Creative Commons
Amr Fouda, Ahmed M. Eid, Mohamed Ali Abdel‐Rahman

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2022, Volume and Issue: 10

Published: Feb. 28, 2022

Herein, the metabolites secreted by brown algae,

Language: Английский

Citations

101

Metal Oxide Nanoparticles: Review of Synthesis, Characterization and Biological Effects DOI Creative Commons
Andreea Mariana Negrescu, Manuela S. Killian, Swathi Naidu Vakamulla Raghu

et al.

Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(4), P. 274 - 274

Published: Dec. 5, 2022

In the last few years, progress made in field of nanotechnology has allowed researchers to develop and synthesize nanosized materials with unique physicochemical characteristics, suitable for various biomedical applications. Amongst these nanomaterials, metal oxide nanoparticles (MONPs) have gained increasing interest due their excellent properties, which a great extent differ from bulk counterpart. However, despite such positive advantages, substantial body literature reports on cytotoxic effects, are directly correlated nanoparticles’ therefore, better control over synthetic parameters will not only lead favorable surface characteristics but may also increase biocompatibility consequently lower cytotoxicity. Taking into consideration enormous potential MONPs, present review discuss most recent developments this referring mainly synthesis methods, physical chemical characterization biological including pro-regenerative antitumor potentials as well antibacterial activity. Moreover, section tackle pressing issue toxic effects MONPs tissues/organs cell lines.

Language: Английский

Citations

94

Green Synthesis of Magnesium Oxide Nanoparticles and Nanocomposites for Photocatalytic Antimicrobial, Antibiofilm and Antifungal Applications DOI Open Access
Marzieh Ramezani Farani, Majid Farsadrooh, Iman Zare

et al.

Catalysts, Journal Year: 2023, Volume and Issue: 13(4), P. 642 - 642

Published: March 23, 2023

Magnesium oxide nanoparticles (MgO NPs) have emerged as potential materials for various biomedical applications due to their unique physicochemical properties, including biodegradability, biocompatibility, cationic capacity, high stability and redox properties. MgO NPs become an attractive platform combat microbes may be a promising alternative overcome challenges associated with eliminating microbial biofilms antibiotic resistance. Hence, the increasing use of in biomedicine, new synthetic strategies are necessary. synthesised using green methods non-toxic, eco-friendly wide range biological, medical catalytic applications. This review presents recent advances biosynthesis by diverse bio-templates, such plant, bacterial, fungal algal extracts. Its photocatalytic properties show suitable inhibitory function against pathogenic agents, proliferation, biofilm formation growth. Furthermore, relevant nanocomposites comprehensively discussed regarding mechanisms effect on microbes, strains, well future perspectives.

Language: Английский

Citations

90

A critical review on the bio-mediated green synthesis and multiple applications of magnesium oxide nanoparticles DOI

Ngoan Thi Thao Nguyen,

Luan Minh Nguyen, Thuy Thi Thanh Nguyen

et al.

Chemosphere, Journal Year: 2022, Volume and Issue: 312, P. 137301 - 137301

Published: Nov. 18, 2022

Language: Английский

Citations

75

Light enhanced the antimicrobial, anticancer, and catalytic activities of selenium nanoparticles fabricated by endophytic fungal strain, Penicillium crustosum EP-1 DOI Creative Commons
Amr Fouda, Saad S. M. Hassan, Ahmed M. Eid

et al.

Scientific Reports, Journal Year: 2022, Volume and Issue: 12(1)

Published: July 12, 2022

Abstract Selenium nanoparticles (Se-NPs) has recently received great attention over owing to their superior optical properties and wide biological biomedical applications. Herein, crystallographic dispersed spherical Se-NPs were green synthesized using endophytic fungal strain, Penicillium crustosum EP-1 . The antimicrobial, anticancer, catalytic activities of biosynthesized investigated under dark light (using Halogen tungsten lamp, 100 Watt, λ > 420 nm, intensity 2.87 W m −2 ) conditions. effect was dose dependent higher against Gram-positive Gram-negative bacteria as well different Candida spp attained in the presence than obtained Moreover, viabilities two cancer cells (T47D HepG2) highly decreased from 95.8 ± 2.9% 93.4 3.2% those 84.8 46.4 3.3% light-irradiation conditions, respectively. Significant decreases IC 50 values T47D HepG2 at 109.1 3.8 70.4 2.5 µg mL −1 , respectively conditions 19.7 7.2 4.8 4.2 after exposure light-irradiation. photoluminescence activity revealed methylene blue degradation efficiency 89.1 2.1% 210 min UV-irradiation compared 59.7 0.2% 68.1 1.03% stability efficient MB successfully achieved for least five cycles.

Language: Английский

Citations

71

Plant-Based Copper Oxide Nanoparticles; Biosynthesis, Characterization, Antibacterial Activity, Tanning Wastewater Treatment, and Heavy Metals Sorption DOI Open Access
Ahmed M. Eid, Amr Fouda, Saad S. M. Hassan

et al.

Catalysts, Journal Year: 2023, Volume and Issue: 13(2), P. 348 - 348

Published: Feb. 3, 2023

Herein, the aqueous extract of Portulaca oleracea has been used as a safe, cheap, eco-friendly, and applicable scale-up method to bio-fabricate copper oxide nanoparticles (CuO-NPs). The character CuO-NPs were determined using UV-vis spectroscopy, Fourier transform infrared (FT-IR), X-ray diffraction (XRD), Transmission electron microscopy (TEM), Energy dispersive X-ray(EDX), Dynamic light scattering (DLS), zeta potential. Spherical crystalline with size range 5–30 nm at maximum surface plasmon resonance 275 successfully fabricated. main components green-synthesized particles Cu O weight percentages 49.92 28.45%, respectively. A Zeta-potential value −24.6 mV was recorded for CuO-NPs, indicating their high stability. plant-based showed promising antimicrobial catalytic activity in dose-dependent manner. Results that synthesized had efficacy inhibit growth pathogens Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans low MIC values ranges 6.25–25 µg/mL. highest decolorization tanning wastewater attained under sunlight irradiation conditions concentration 2.0 mg/mL after 200 min 88.6 ± 1.5% compared those which dark (70.3 1.2%). physicochemical parameters including total suspended solids (TSS), dissolved (TDS), chemical oxygen demand (COD), biological (BOD), conductivity optimum significantly decreased 95.2, 86.7, 91.4, 87.2, 97.2%, Interestingly, heavy metals cobalt (Co), lead (Pb), nickel (Ni), cadmium (Cd), chromium (Cr (VI)) 73.2, 80.8, 72.4, 64.4, 91.4%, respectively, treatment conditions. Overall, plant-synthesized have activities are considered nano-catalyst environmentally beneficial treatment.

Language: Английский

Citations

69

Green Synthesis of Zinc Oxide Nanoparticles Using an Aqueous Extract of Punica granatum for Antimicrobial and Catalytic Activity DOI Creative Commons
Amr Fouda, Ebrahim Saied, Ahmed M. Eid

et al.

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(4), P. 205 - 205

Published: April 7, 2023

The peel aqueous extract of Punica granatum was utilized to fabricate zinc oxide nanoparticles (ZnO-NPs) as a green approach. synthesized NPs were characterized by UV-Vis spectroscopy, Fourier transform infrared (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning microscopy, which attached an energy dispersive (SEM-EDX). Spherical, well arranged, crystallographic structures ZnO-NPs formed with sizes 10-45 nm. biological activities ZnO-NPs, including antimicrobial catalytic activity for methylene blue dye, assessed. Data analysis showed that the against pathogenic Gram-positive Gram-negative bacteria, unicellular fungi, observed occur in dose-dependent manner, displaying varied inhibition zones low minimum inhibitory concentration (MIC) values ranges 6.25-12.5 µg mL-1. degradation efficacy (MB) using is dependent on nano-catalyst concentration, contact time, incubation condition (UV-light emission). maximum MB percentages 93.4 ± 0.2% attained at 20 mL-1 after 210 min presence UV-light. there no significant difference between 210, 1440, 1800 min. Moreover, high stability degrade five cycles decreasing 4%. Overall, P. granatum-based are promising tools inhibit growth microbes UV-light emission.

Language: Английский

Citations

53

Exploring the antimicrobial, antioxidant, anticancer, biocompatibility, and larvicidal activities of selenium nanoparticles fabricated by endophytic fungal strain Penicillium verhagenii DOI Creative Commons

Abdel-Rahman A. Nassar,

Ahmed M. Eid,

Hossam M. Atta

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: June 3, 2023

Herein, four endophytic fungal strains living in healthy roots of garlic were used to produce selenium nanoparticles (Se-NPs) via green synthesis. Penicillium verhagenii was found be the most efficient Se-NPs producer with a ruby red color that showed maximum surface plasmon resonance at 270 nm. The as-formed crystalline, spherical, and well-arranged without aggregation, ranged from 25 75 nm size zeta potential value -32 mV, indicating high stability. Concentration-dependent biomedical activities P. verhagenii-based observed, including promising antimicrobial activity against different pathogens (Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Candida albicans, C. glabrata, tropicalis, parapsilosis) minimum inhibitory concentration (MIC) 12.5-100 µg mL-1. biosynthesized antioxidant DPPH-scavenging percentages 86.8 ± 0.6% 1000 mL-1 decreased 19.3 4.5% 1.95 Interestingly, also anticancer PC3 MCF7 cell lines IC50 225.7 3.6 283.8 7.5 mL-1, respectively while it is remaining biocompatible normal WI38 Vero lines. Additionally, synthesized effective instar larvae medical insect, Aedes albopictus mortality 85.1 3.1, 67.2 1.2, 62.10 1.4, 51.0 1.0% 50 for I, II, III, IV-instar larva, respectively. These data highlight efficacy cost-effective eco-friendly synthesis applications.

Language: Английский

Citations

53