Melatonin-mediated temperature stress tolerance in plants

GM crops & food, Journal Year: 2022, Volume and Issue: 13(1), P. 196 - 217

Published: Aug. 19, 2022

Global climate changes cause extreme temperatures and a significant reduction in crop production, leading to food insecurity worldwide. Temperature extremes (including both heat cold stresses) is one of the most limiting factors plant growth development severely affect physiology, biochemical, molecular processes. Biostimulants like melatonin (MET) have multifunctional role that acts as “defense molecule” safeguard plants against noxious effects temperature stress. MET treatment improves tolerance by improving several defense mechanisms. Current research also suggests interacts with other molecules, phytohormones gaseous which greatly supports adaptation Genetic engineering via overexpression or CRISPR/Cas system biosynthetic genes uplifts levels transgenic enhances stress tolerance. This review highlights critical production We documented how molecules alleviate MET-mediated breeding would be great potential helping adverse creating plants.

Language: Английский

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Functions and prospects of melatonin in plant growth, yield, and quality

Journal of Experimental Botany, Journal Year: 2022, Volume and Issue: 73(17), P. 5928 - 5946

Published: May 30, 2022

Abstract Melatonin (N-acetyl-5-methoxytryptamine) is an indole molecule widely found in animals and plants. It well known that melatonin improves plant resistance to various biotic abiotic stresses due its potent free radical scavenging ability while being able modulate signaling response pathways through mostly unknown mechanisms. In recent years, increasing number of studies have shown plays a crucial role improving crop quality yield by participating the regulation aspects growth development. Here, we review effects on vegetative reproductive development, systematically summarize molecular regulatory network. Moreover, effective concentrations exogenously applied different crops or at stages same are analysed. addition, compare endogenous phytomelatonin organs, evaluate potential function circadian rhythms. The prospects approaches regulating exogenous application appropriate melatonin, modification metabolism-related genes, use nanomaterials other technologies improve utilization efficiency also discussed.

Language: Английский

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Protective Role of Melatonin and Its Metabolites in Skin Aging

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(3), P. 1238 - 1238

Published: Jan. 22, 2022

The skin, being the largest organ in human body, is exposed to environment and suffers from both intrinsic extrinsic aging factors. skin process characterized by several clinical features such as wrinkling, loss of elasticity, rough-textured appearance. This complex accompanied with phenotypic functional changes cutaneous immune cells, well structural disturbances extracellular matrix components collagens elastin. Because health considered one principal factors representing overall “well-being” perception “health” humans, anti-aging strategies have recently been developed. Thus, while fundamental mechanisms regarding are known, new substances should be for introduction into dermatological treatments. Herein, we describe melatonin its metabolites potential “aging neutralizers”. Melatonin, an evolutionarily ancient derivative serotonin hormonal properties, main neuroendocrine secretory product pineal gland. It regulates circadian rhythmicity also exerts anti-oxidative, anti-inflammatory, immunomodulatory, anti-tumor capacities. intention this review summarize within aging, research advances on molecular leading these changes, impact melatoninergic anti-oxidative system controlled metabolites, targeting prevention or reversal aging.

Language: Английский

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Melatonin and Abiotic Stress Tolerance in Crop Plants

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(8), P. 7447 - 7447

Published: April 18, 2023

Increasing food demand by the growing human population and declining crop productivity due to climate change affect global security. To meet challenges, developing improved crops that can tolerate abiotic stresses is a priority. Melatonin in plants, also known as phytomelatonin, an active component of various cellular mechanisms alleviates oxidative damage hence supporting plant survive stress conditions. Exogenous melatonin strengthens this defence mechanism enhancing detoxification reactive by-products, promoting physiological activities, upregulating stress-responsive genes alleviate during stress. In addition its well-known antioxidant activity, protects against regulating hormones, activating ER genes, increasing protein homoeostasis, heat shock transcription factors proteins. Under stress, enhances unfolded response, endoplasmic reticulum-associated degradation, autophagy, which ultimately protect cells from programmed cell death promotes repair resulting increased survival.

Language: Английский

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From challenges to solutions: The impact of melatonin on abiotic stress synergies in horticultural plants via redox regulation and epigenetic signaling

Scientia Horticulturae, Journal Year: 2023, Volume and Issue: 321, P. 112369 - 112369

Published: July 31, 2023

Language: Английский

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Transcriptomic and metabolomic analysis reveals the molecular mechanism of exogenous melatonin improves salt tolerance in eggplants

Frontiers in Plant Science, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 10, 2025

Melatonin significantly enhances the tolerance of plants to biotic and abiotic stress, plays an important role in plant resistance salt stress. However, its molecular mechanisms eggplant stress have been rarely reported. In previous studies, we experimentally demonstrated that melatonin can enhance eggplants. this study, treated salt-stressed with a control treatment water, then conducted physiological biochemical tests, transcriptomic metabolomic sequencing, RT-qPCR validation at different stages after treatment. The results showed exogenous alleviate adverse effects on by increasing activity antioxidant enzymes, reducing content reactive oxygen species plants, organic osmoprotectants. Transcriptomic data, as well combined analysis, indicate activate metabolic pathways Compared genes α-linolenic acid metabolism pathway promote accumulation metabolites pathway, significant observed 48 hours treatment, activates expression such SmePLA2, SmeLOXs SmeOPR et al. α-Linolenic acid, (9R,13R)-12-oxophytodienoic 9(S)-HpOTrE (+)-7-iso-Jasmonic acid. validated activating effect candidate a-linolenic pathway. This study analyzed mechanism alleviating providing theoretical foundation for application enhancing production.

Language: Английский

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Melatonin as a regulator of plant ionic homeostasis: implications for abiotic stress tolerance

Journal of Experimental Botany, Journal Year: 2022, Volume and Issue: 73(17), P. 5886 - 5902

Published: May 30, 2022

Abstract Melatonin is a highly conserved and ubiquitous molecule that operates upstream of broad array receptors in animal systems. Since melatonin was discovered plants 1995, hundreds papers have been published revealing its role plant growth, development, adaptive responses to the environment. This paper summarizes current state knowledge melatonin’s involvement regulating ion homeostasis abiotic stress tolerance. The major topics covered here are: (i) control H+-ATPase activity implication for various stresses; (ii) regulation reactive oxygen species (ROS)–Ca2+ hub by signaling; (iii) ionic via hormonal cross-talk. We also show properties allow direct scavenging ROS, thus preventing negative effects ROS-induced activation channels. above ‘desensitization’ may play critical stress-induced K+ loss from cytosol as well maintaining basic levels cytosolic Ca2+ required optimal cell operation. Future studies should focus on molecular identity transporters could be directly regulated providing bioinformatic analysis evolutionary aspects sensing signaling.

Language: Английский

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Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective

Journal of Pineal Research, Journal Year: 2022, Volume and Issue: 72(3)

Published: Feb. 8, 2022

The evolutionarily ancient methoxyindoleamine, melatonin, has long perplexed investigators by its versatility of functions and mechanisms action, which include the regulation vertebrate pigmentation. Although first discovered through potent skin-lightening effects in amphibians, melatonin's role human skin hair follicle pigmentation impact on melanocyte physiology remain unclear. Synthesizing our limited current understanding this role, we specifically examine melanogenesis, oxidative biology, mitochondrial function, senescence, pigmentation-related clock gene activity, with emphasis skin, yet without ignoring instructive pointers from nonhuman species. Given strict dependence epithelial microenvironment, underscore that responses to melatonin are best interrogated a physiological tissue context. Current evidence suggests some metabolites inhibit both, melanogenesis (via reducing tyrosinase activity) proliferation stimulating membrane receptors (MT1, MT2). We discuss whether putative melanogenesis-inhibitory may occur via activation Nrf2-mediated PI3K/AKT signaling, estrogen receptor-mediated and/or melanocortin-1 receptor- cAMP-dependent melatonin-regulated changes peripheral genes regulate namely Bmal1 Per1. Melatonin also accumulate melanocytes where they exert net cyto- senescence-protective as well antioxidative operating free radical scavengers, synthesis activity ROS scavenging enzymes other antioxidants, promoting DNA repair, enhancing function. argue it is clinically biologically important definitively clarify cell culture-based observations translate into melatonin-induced pigmentary context, is, epidermis follicles ex vivo, confirmed clinical trial results. After defining major open questions field, close suggesting how begin answering them relevant, currently available preclinical situ research models.

Language: Английский

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The role of melatonin in tomato stress response, growth and development

Plant Cell Reports, Journal Year: 2022, Volume and Issue: 41(8), P. 1631 - 1650

Published: May 16, 2022

Language: Английский

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Biosynthetic Pathways of Hormones in Plants

Metabolites, Journal Year: 2023, Volume and Issue: 13(8), P. 884 - 884

Published: July 25, 2023

Phytohormones exhibit a wide range of chemical structures, though they primarily originate from three key metabolic precursors: amino acids, isoprenoids, and lipids. Specific such as tryptophan, methionine, phenylalanine, arginine, contribute to the production various phytohormones, including auxins, melatonin, ethylene, salicylic acid, polyamines. Isoprenoids are foundation five phytohormone categories: cytokinins, brassinosteroids, gibberellins, abscisic strigolactones. Furthermore, lipids, i.e., α-linolenic function precursor for jasmonic acid. The biosynthesis routes these different plant hormones intricately complex. Understanding processes can greatly enhance our knowledge how regulate growth, development, physiology. This review focuses on detailing biosynthetic pathways phytohormones.

Language: Английский

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