COVID-19 on Oral Health: A New Bilateral Connection for the Pandemic

Biomedicines, Journal Year: 2023, Volume and Issue: 12(1), P. 60 - 60

Published: Dec. 26, 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and transmission are generally known to be produced by droplets aerosols from the oral cavity (O.C.) of infected subjects, as stated World Health Organization. Saliva also retains viral particles aids in spread COVID-19. Angiotensin-converting enzyme Type (ACE2) transmembrane serine protease (TMPRSS2) two numerous factors that promote SARS-CoV-2 infection, expressed O.C. structures, various mucosa types, epithelia salivary glands. A systemic might result replication cells. On other hand, cellular damage different subtypes associated with clinical signs symptoms. Factors interfering potential represent fertile ground for possible local pharmacotherapeutic interventions, which may confine virus entry O.C., finally representing a way reduce COVID-19 incidence severity.

Language: Английский

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Oral SARS‐CoV‐2 reduction by local treatment: A plasma technology application?

Plasma Processes and Polymers, Journal Year: 2022, Volume and Issue: 20(3)

Published: Dec. 22, 2022

Abstract The SARS‐CoV‐2 pandemic reemphasized the importance of and need for efficient hygiene disinfection measures. coronavirus' spread capitalizes on its airborne transmission routes via virus aerosol release from human oral nasopharyngeal cavities. Besides upper respiratory tract, viral replication has been described in epithelium these two body To this end, idea emerged to employ plasma technology locally reduce mucosal loads as an additional measure patient infectivity. We here outline conceptual ideas such treatment concepts within what is known antiviral actions so far.

Language: Английский

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Complete Blood Count and saliva parameters as an indicator for infected patients with coronavirus covid-19

Journal of Baghdad College of Dentistry, Journal Year: 2023, Volume and Issue: 35(1), P. 76 - 85

Published: March 15, 2023

Background: Coronavirus, which causes respiratory illness, has been a public health issue in recent decades. Because the clinical symptoms of infection are not always specific, it is difficult to expose all suspects qualitative testing order confirm or rule out as test. Methods: According scientific studies and investigations, seventy-three results articles research were obtained using PubMed, Medline, Research gate Google Scholar. The keywords used COVID-19, coronavirus, blood parameters, saliva. Results: This review provides report on changes saliva tests those who infected with COVID-19.COVID-19 systemic that substantial influence hematological system hemostasis, thus deviations from normal levels laboratory tests, including test show specific for detecting COVID-19 required. Conclusions: aid monitoring patient's health. It advantages such following: non-invasive properties, low cost, good stability, addition minimum risk transport.

Language: Английский

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Significance of chlorine‐dioxide‐based oral rinses in preventing SARS‐CoV‐2 cell entry

Oral Diseases, Journal Year: 2022, Volume and Issue: 28(S2), P. 2481 - 2491

Published: July 16, 2022

This work aims to determine the efficacy of preprocedural oral rinsing with chlorine dioxide solutions minimize risk coronavirus disease 2019 (COVID-19) transmission during high-risk dental procedures.The antiviral activity chlorine-dioxide-based rinse (OR) was tested by pre-incubating severe acute respiratory syndrome 2 (SARS-CoV-2) pseudovirus in a dosage-dependent manner before transducing human embryonic kidney epithelial (HEK293T-ACE2) cells, which stably expresses ACE-2 receptor. Viral entry determined measuring luciferase using luminescence microplate reader. In cell-to-cell fusion assay, effector Chinese hamster ovary (CHO-K1) cells co-expressing spike glycoprotein SARS-CoV-2 and T7 RNA polymerase were pre-incubated ORs co-culturing target CHO-K1 ACE2 receptor gene. The signal quantified 24 h after mixing cells. Surface expression confirmed direct fluorescent imaging quantitative cell-ELISA. Finally, cytotoxic effects evaluated at two different time points.A effect observed against cell mediated fusion. demonstrates that can be useful as step reduce viral infectivity.Chlorine-dioxide-based have potential benefit for reducing spread.

Language: Английский

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Manifestaciones orales del COVID-19 en Paraguay: resultados de una encuesta en línea.

Medicina Clínica y Social, Journal Year: 2024, Volume and Issue: 8(1), P. 91 - 96

Published: Jan. 9, 2024

Introducción: Estudios previos han reportado que pacientes infectados con el virus del COVID-19, podrían manifestar sintomatologías a nivel de la cavidad oral. Objetivo: Evaluar frecuencia manifestaciones orales asociadas COVID-19 en un segmento población paraguaya y determinar cuáles son las más prevalentes. Metodología: Estudio descriptivo corte transversal. Fue realizada una encuesta electrónica enero marzo 2022. Los datos fueron presentados como frecuencias porcentajes analizados mediante prueba chi-cuadrado. El análisis estadístico se realizó software R versión 4.0.3. Resultados: La muestra estuvo compuesta por 478 personas. 79,50 % correspondió al sexo femenino 45,19 tenía entre 25 34 años. 65,48 informó haber experimentado menos 1 síntoma o signo oral durante curso COVID-19. pérdida sensación sabores amargos, seguida alteración sabor los alimentos percepción dulce, síntomas comunes. Se encontró proporción significativamente mayor rango 18-24 años (?²; p= 0,003). Entre personas desarrollaron forma moderada severa hubo número 0,044). Discusión: identificó alta casos moderados severos destacándose trastornos gusto predominantes. individuos jóvenes afectados.

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