The Research Progress of Vascular Aging Related Diseases DOI Open Access
Shan Wang,

Jia Liu,

Zi‐Wei Cui

et al.

Journal of Innovations in Medical Research, Journal Year: 2023, Volume and Issue: 2(6), P. 36 - 44

Published: June 1, 2023

The aging-related factors of population, environment, physical inactivity and unhealthy diet have emerged as significant contributors to the onset vascular aging, which poses a crucial risk for various diseases including hypertension, coronary heart disease, failure stroke. structural, phenotypic, functional changes in vasculature resulting from aging are critical pathogenesis diseases. Numerous molecular cellular phenomena, oxidative stress, mitochondrial dysfunction, inflammation, senescence, epigenetic alterations, closely linked pathophysiology aging. Given escalating hospitalization rates attributed illness, need efficacious interventions counteract decline function is becoming increasingly pressing. This review provides an overview recent developments disorders, encompassing cardiovascular diseases, neurodegenerative chronic kidney sarcopenia. Furthermore, comprehensive examination conducted, implementation intervention strategies (including drug lifestyle interventions) can effectively mitigate progression ailments, thereby facilitating achievement healthy longevity.

Language: Английский

The Research Progress of Vascular Aging Related Diseases DOI Open Access
Shan Wang,

Jia Liu,

Zi‐Wei Cui

et al.

Journal of Innovations in Medical Research, Journal Year: 2023, Volume and Issue: 2(6), P. 36 - 44

Published: June 1, 2023

The aging-related factors of population, environment, physical inactivity and unhealthy diet have emerged as significant contributors to the onset vascular aging, which poses a crucial risk for various diseases including hypertension, coronary heart disease, failure stroke. structural, phenotypic, functional changes in vasculature resulting from aging are critical pathogenesis diseases. Numerous molecular cellular phenomena, oxidative stress, mitochondrial dysfunction, inflammation, senescence, epigenetic alterations, closely linked pathophysiology aging. Given escalating hospitalization rates attributed illness, need efficacious interventions counteract decline function is becoming increasingly pressing. This review provides an overview recent developments disorders, encompassing cardiovascular diseases, neurodegenerative chronic kidney sarcopenia. Furthermore, comprehensive examination conducted, implementation intervention strategies (including drug lifestyle interventions) can effectively mitigate progression ailments, thereby facilitating achievement healthy longevity.

Language: Английский

Citations

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