Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: May 13, 2025
Language: Английский
Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15
Published: March 11, 2024
Background Physical activity significantly influences health-related behaviors, encompassing physical and mental well-being. has been linked to enhancing health behavior, health, psychological resilience. The current study is based on participants who were active in improve Objectives To examine the of resilience, considering moderating role quality life. Method A thorough cross-sectional online survey was conducted from April 15, 2023, October 2023. comprehensive lasted for six months. poll received more than one thousand responses under convenience sampling. selection criteria above 21 years old, collected data analyzed using appropriate statistical SPSS-25 SmartPLS 4.0 software investigate proposed research paradigm. Results SEM results model 1 (direct coefficients) show that PA a positive effect HeB, MeH, PsR, HeB PsR. Out (in 2), four effects QOL significant, two statistically insignificant. Conclusion It observed life relationships between exercise several aspects, such as behavior. imperative emphasize importance fostering consistent engagement cultivate well-balanced health-conscious way
Language: Английский
Citations
25
Experimental Gerontology, Journal Year: 2024, Volume and Issue: 195, P. 112539 - 112539
Published: Aug. 8, 2024
Neurodegenerative diseases (NDDs) are a class of neurological disorders marked by the progressive loss neurons that afflict millions people worldwide. These illnesses affect brain connection, impairing memory, cognition, behavior, sensory perception, and motor function. Alzheimer's, Parkinson's, Huntington's examples common NDDs, which frequently include buildup misfolded proteins. Cognitive-behavioral impairments early markers neurodevelopmental disorders, emphasizing importance detection intervention. Neurotrophins such as brain-derived neurotrophic factor (BDNF) critical for neuron survival synaptic plasticity, is required learning memory. NDDs have been associated with decreased BDNF levels. Physical exercise, non-pharmacological intervention, benefits health increasing levels, lowering cognitive deficits, slowing degradation. Exercise advantages increased well-being, reduced depression, improved skills, neuroprotection amyloid accumulation, oxidative stress, neuroinflammation. This study examines effects physical exercise on cognitive-behavioral deficits levels in limbic system impacted neurodegeneration. The findings highlight necessity including into NDD treatment to improve structure, function, total As research advances, becoming increasingly acknowledged an important technique treating decline neurodegenerative disorders.
Language: Английский
Citations
15
International Journal of Behavioral Nutrition and Physical Activity, Journal Year: 2025, Volume and Issue: 22(1)
Published: March 10, 2025
Abstract Background Frailty has become an important health problem in the middle-aged and older people population. Physical activity (PA) is a key intervention for frailty prevention management. However, studies of association between COVID-19 pre-pandemic PA worsening or improvement during pandemic remain unclear. Methods This longitudinal cohort study used data from English Longitudinal Study Ageing (ELSA), including participants aged 50 over. Three intensities (vigorous, moderate, mild) were categorized as less than once per week at least week, respectively, based on participant self-report. The index (FI) assessed status, defining FI ≥ 25. Logistic regression was applied to examine frailty, estimating odds ratios (OR) 95% confidence intervals (95% CI). Results Of 4379 non-frail baseline (median age 67, 54.9% female), 8.1% developed mean follow-up 3.5 years. Among 564 frail 71, 66.5% 17.9% regained health. Compared those engaging who engaged vigorous (OR: 0.47 [95% CI: 0.35–0.62]), moderate 0.37 0.29–0.48]), mild 0.38 0.26–0.56]) had lower risk worsening. Additionally, 2.04 1.29–3.21]) 2.93 1.54–5.58]) higher likelihood improvement. Sensitivity analyses comprehensive levels confirmed these findings. Participants maintained one (Vigorous, OR: 0.20 [95%CI: 0.12–0.33]; Moderate, 0.13 0.09–0.19]; Mild, 0.11–0.38]) rates (Moderate, 3.43 1.93–6.11]; 4.65 1.90-11.42]). In addition, individuals 0.35 0.20–0.60]; 0.36 0.22–0.56]) transitioned inactive active also exhibited frailty. Conclusions emphasized critical role preventing improving people, especially pandemic. Our highlighted importance maintaining habits reduce promote its Also, indicated that These findings enriched understanding provided valuable insights addressing impact future pandemics people.
Language: Английский
Citations
1
BMC Psychology, Journal Year: 2024, Volume and Issue: 12(1)
Published: Aug. 13, 2024
Social anxiety symptoms are common and harmful psychological illness in college students. Although some studies have illustrated that physical activity could reduce social symptoms, the specific mechanism is still unclear. Based on theoretical resilience sleep, this study constructed a serial mediation model to explore whether they mediate between among This surveyed 9,530 students from three colleges China mediating effect of sleep problems symptoms. Participants were investigated with International Physical Activity Questionnaire, Connor-Davidson Resilience Scale, Sleep-related problems, Interaction Anxiety Scale Phobia Scale. Correlations variables analysed using Pearson correlation analysis analyses performed SPSS PROCESS macro 3.3 software. The found was negatively associated but positively resilience. After controlling for sociodemographic variables, can not only indirectly alleviate through separate also problems. These results suggest improving levels scores by increasing quality. great reference significance prevention intervention students' mental health.
Language: Английский
Citations
7
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11602 - 11602
Published: Oct. 29, 2024
This narrative review examines the relationship between dopamine-related genetic polymorphisms, personality traits, and athletic success. Advances in sports genetics have identified specific single nucleotide polymorphisms (SNPs) genes linked to traits crucial for performance, such as motivation, cognitive function, emotional resilience. clarifies how variations can influence predisposition through dopaminergic pathways environmental interactions. Key findings reveal associations SNPs enhanced performance various sports. For example, COMT Val158Met rs4680 BDNF Val66Met rs6265 are associated with that could benefit increased focus, stress resilience conscientiousness, especially martial arts. DRD3 rs167771 is higher agreeableness, benefiting teamwork like football. synthesis underscores multidimensional role of shaping ability advocates integrating profiling into personalized training optimize well-being. However, research gaps remain, including need standardized protocols exploring gene–environment interactions diverse populations. Future studies should focus on epigenetic factors inform tailored interventions enhance both physical psychological aspects performance. By bridging genetics, psychology, exercise science, this paves way innovative optimization strategies.
Language: Английский
Citations
7
Healthcare, Journal Year: 2023, Volume and Issue: 11(5), P. 695 - 695
Published: Feb. 26, 2023
Objective: To explore the relationship between psychological stress and emotional state of Chinese college students moderating effect physical exercise. Methods: Students in a university Jiangsu Province were randomly selected for survey, questionnaires administered using Physical Activity Rating Scale, Profile Mood States, College Student Psychological Stress Scale. A total 715 distributed, 494 valid returned. Among students, there 208 (42.1%) males 286 (57.9%) females, with mean age 19.27 years (SD = 1.06). Results: We found significant negative correlation exercise (r −0.637, p < 0.001); −0.032, positive 0.51, 0.001). negatively moderates (B −0.012, 0.01, ΔR2 0.007). Conclusion: is correlated both stress. can reduce influence on promote health.
Language: Английский
Citations
13
Neuroscience Applied, Journal Year: 2024, Volume and Issue: 3, P. 104064 - 104064
Published: Jan. 1, 2024
Stress, encompassing psychological, physical, and physiological challenges, is an important factor affecting individual's well-being potentially leading to psychiatric, neurodegenerative, immune, metabolic disorders. However, not everyone exposed stress develops these conditions, highlighting the concept of resilience. Resilience a dynamic process categorized into four dimensions: pre-existing resilience capacity, ongoing processes, post-stress outcomes, recovery from psychopathologies. These dimensions involve genomic, cellular, systemic interactions influenced by genetic factors, early life experiences, adult experiences in addition community/environmental health behaviors. The biological response encompasses endocrine, autonomic, immunological, behavioral components, modulated stressor characteristics individual traits. Due limitations studying humans, translational models using rodents cell cultures are essential. Rodent include acute, chronic, traumatic paradigms, aiding study stress-related molecular outcomes. Additionally, models, such as prenatal maternal separation, provide insights developmental impacts. In this review, first, rodent for lifelong exposure will be summarized considering their validity, advantages, limitations. Subsequently, overview designed enhance capacity rodents, later employed outcomes given. Lastly, focus shifted culture iPSCs models. Finally, future considerations focused on improving used discussed. It aimed designs access more effective biomarkers associated with Stress complex phenomena various spanning levels. Integrating data across remains crucial unraveling complexities disorders
Language: Английский
Citations
4
Current Neuropharmacology, Journal Year: 2023, Volume and Issue: 22(4), P. 543 - 556
Published: July 26, 2023
Brain-Derived Neurotrophic Factor (BDNF) plays an important role in brain development, neural plasticity, and learning memory. The Val66Met single-nucleotide polymorphism is a common genetic variant that results deficient activity-dependent release of BDNF. This its impact on fear conditioning extinction, as well symptoms post-traumatic stress disorder (PTSD), have been increasing research interest over the last two decades. More recently, it has demonstrated regular physical activity may ameliorate impairments extinction alleviate individuals with PTSD via action BDNF levels there are differential responses to exercise between genotypes. narrative literature review first describes theoretical underpinnings development persistence intrusive hypervigilance commonly seen their treatment. It then discusses recent involvement diagnosis severity. Finally, investigates secretion, differences genotypes, effect memory PTSD.
Language: Английский
Citations
10
Psychopharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 7, 2025
Language: Английский
Citations
0
Biomedical Reports, Journal Year: 2025, Volume and Issue: 22(3)
Published: Jan. 14, 2025
Depression and coronary heart disease (CHD) are two interconnected diseases that profoundly impact global health. is both a complex psychiatric disorder an established risk factor for CHD. Sirtuin 1 (SIRT1) enzyme requires the cofactor nicotinamide adenine dinucleotide (NAD+) to perform its deacetylation function, involvement crucial in reducing cardiovascular risks associated with depression. SIRT1 exerts cardioprotective effects via modulating oxidative stress, inflammation metabolic processes, all of which central pathogenesis CHD individuals Through influencing these pathways, helps reduce endothelial dysfunction, prevent formation atherosclerotic plaques stabilize existing plaques, thereby decreasing overall The present review underscores important role serving as therapeutic intervention molecule tackling complications stemming from Furthermore, it highlights need further studies clarify how influences depression at molecular level. ultimate goal this research will be translate findings into practical clinical strategies.
Language: Английский
Citations
0