Hydrogen sulfide antagonizes cytokinin to change root system architecture through persulfidation of CKX2 in Arabidopsis DOI
Xiuyu Wang, Cuixia Liu, Tian Li

et al.

New Phytologist, Journal Year: 2024, Volume and Issue: 244(4), P. 1377 - 1390

Published: Sept. 15, 2024

Summary Hydrogen sulfide (H 2 S) is an endogenous gaseous signaling molecule, which has been shown to play important role in plant growth and development by coupling with various phytohormones. However, the relationship between H S cytokinin (CTK) mechanisms CTK affect root remain poorly understood. Endogenous was analyzed UHPLC‐ESI‐MS/MS. Persulfidation of oxidase/dehydrogenases (CKXs) mass spectrometry (MS). ckx2/CKX2 wild‐type (WT) , OE CKX2 Cys(C)62alanine(A) transgenic lines were isolated ckx2 background. linked content CKX2, regulates system architecture (RSA). at cysteine (Cys)62 residue enhances activity, resulting reduced content. We utilized 35S‐LCD/oasa1 investigate effect on RSA, indicating that reduces gravitropic set‐point angle (GSA), shortens hairs, increases number lateral roots (LRs). The persulfidation Cys62 changes elongation cells upper lower flanks LR zone, confirming specificity target regulate RSA vivo . In conclusion, this study demonstrated negatively affects Arabidopsis thaliana

Language: Английский

Hydrogen sulfide signaling in plant response to temperature stress DOI Creative Commons
Zhong‐Guang Li,

Jue-Rui Fang,

Su-Jie Bai

et al.

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: March 13, 2024

For the past 300 years, hydrogen sulfide (H 2 S) has been considered a toxic gas. Nowadays, it found to be novel signaling molecule in plants involved regulation of cellular metabolism, seed germination, plant growth, development, and response environmental stresses, including high temperature (HT) low (LT). As molecule, H S can actively synthesized degraded cytosol, chloroplasts, mitochondria cells by enzymatic non-enzymatic pathways maintain homeostasis. To date, receptors for have not found. It usually exerts physiological functions through persulfidation target proteins. In 10 gained much attention. Therefore, this review, based on that same attention, homeostasis, protein persulfidation, role HT LT stress were summarized. Also, common mechanisms S-induced tolerance updated. These involve restoration biomembrane integrity, synthesis proteins, enhancement antioxidant system methylglyoxal (MG) detoxification system, improvement water homeostasis reestablishment Ca 2+ acid-base balance. updates lay foundation further understanding acquiring temperature-stress-resistant crops develop sustainable food agriculture.

Language: Английский

Citations

24
Hydrogen sulfide mechanism of action in plants; from interaction with regulatory molecules to persulfidation of proteins DOI

Shirin Mohammadbagherlou,

Elaheh Samari,

Mostafa Sagharyan

et al.

Nitric Oxide, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

2
Hydrogen Sulfide: An Emerging Regulator of Oxidative Stress and Cellular Homeostasis—A Comprehensive One-Year Review DOI Creative Commons
Constantin Munteanu, Marius Turnea, Mariana Rotariu

et al.

Antioxidants, Journal Year: 2023, Volume and Issue: 12(9), P. 1737 - 1737

Published: Sept. 7, 2023

Hydrogen sulfide (H2S), traditionally recognized as a toxic gas, has emerged critical regulator in many biological processes, including oxidative stress and cellular homeostasis. This review presents an exhaustive overview of the current understanding H2S its multifaceted role mammalian functioning management. We delve into sources function H2S, mechanisms underlying homeostasis, intricate relationships between these processes. explore evidence from recent experimental clinical studies, unraveling biochemical molecular dictating H2S’s roles modulating responses maintaining The implications therapeutic potential conditions characterized by dysregulation disrupted homeostasis are discussed, highlighting emerging significance health disease. Finally, this underscores challenges, controversies, future directions field, emphasizing need for further research to harness agent diseases associated with homeostatic imbalance. Through review, we aim emphasize pivotal function, encouraging exploration burgeoning area research.

Language: Английский

Citations

35
Hydrogen Sulfide Signaling in Plants DOI
Jingjing Huang,

Yanjie Xie

Antioxidants and Redox Signaling, Journal Year: 2023, Volume and Issue: 39(1-3), P. 40 - 58

Published: March 16, 2023

Significance: Hydrogen sulfide (H2S) is a multitasking potent regulator that facilitates plant growth, development, and responses to environmental stimuli. Recent Advances: The important beneficial effects of H2S in various aspects physiology aroused the interest this chemical for agriculture. Protein cysteine persulfidation has been recognized as main reduction-oxidation (redox) regulatory mechanism signaling. An increasing number studies, including large-scale proteomic analyses functional characterizations, have revealed H2S-mediated persulfidations directly regulate protein functions, altering downstream signaling plants. To date, importance several abscisic acid signaling-controlling key proteins assessed well their role stomatal movements, largely contributing understanding H2S-regulatory mechanism. Critical Issues: molecular mechanisms sensing transduction plants remain elusive. correlations with other oxidative post-translational modifications cysteines are still be explored. Future Directions: Implementation advanced detection approaches spatiotemporal monitoring levels cells current profiling strategies identification quantification site-specific will provide insight into Antioxid. Redox Signal. 39, 40-58.

Language: Английский

Citations

24
The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium DOI Creative Commons
Coral Pardo-Esté,

Francisca Urbina,

Nicolas Aviles

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 11, 2025

The ArcAB two-component system includes a histidine kinase sensor (ArcB) and regulator (ArcA) that respond to changes in cell oxygen availability. ArcA transcription factor activates genes related metabolism, membrane permeability, virulence, its presence is required for pathogenicity Salmonella Typhimurium, which can be phosphorylated independently of cognate sensor, ArcB. In this study, we aimed characterize the transcriptional response hypochlorous acid (HOCl) mediated by ArcB sensor. HOCl powerful microbicide widely used sanitization industrial settings. We wild-type S. Typhimurium mutant lacking arcB gene exposed NaOCl describe global response. also infected murine neutrophils evaluate expression levels relevant resistance infection process while facing ROS-related stress. Our results indicate absence significantly affects ability grow under Overall, 6.6% varied their strains, 8.6% changed NaOCl. associated with metabolism suggesting critical role fitness, especially show influences fatty degradation, protein secretion, cysteine H 2 S biosynthesis, translation, both vitro conditions found within neutrophils. carbonylation higher strain than wild type, function repair processes. This study contributes understanding adaptation mechanisms employs establish successful host.

Language: Английский

Citations

1
“Light-Up” Near-Infrared Fluorescent Probe for Visualization of Hydrogen Sulfide Content and Abiotic Stress Response in Plants DOI

Chenglin Su,

Renguo Zhang,

Yining Sun

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: 73(9), P. 5614 - 5624

Published: Feb. 20, 2025

Hydrogen sulfide (H2S) plays a vital role in plant physiology and stress adaptation, but the detection of endogenous H2S remains challenge. In this work, near-infrared fluorescent probe (NIR-BOD-HS) was synthesized using boron-dipyrromethene (BODIPY) as raw material, which showed good linear relationship concentration range 0.1-70 μM limit 56 nM. The long-wavelength emission (712 nm) reduced interference autofluorescence improved imaging quality. combined with fluorescence technology nondestructively realized spatiotemporal distribution signal deep tissues plants. addition, dynamic changes content during seed germination seedling growth under abiotic were also demonstrated through signals. This study helps to understand physiological response mechanism plants provides scientific basis for further research on agricultural production.

Language: Английский

Citations

1
Synergistic effects of hydrogen sulfide and nitric oxide in enhancing salt stress tolerance in cucumber seedlings DOI
Ritu Kumari, M. Nasir Khan, Zubair Ahmad Parrey

et al.

Physiologia Plantarum, Journal Year: 2025, Volume and Issue: 177(1)

Published: Jan. 1, 2025

Abstract Salinity stress poses a significant threat to plant growth and agricultural productivity, affecting millions of hectares land worldwide. The adverse effects salt toxicity, primarily caused by high levels sodium chloride in soil water, disrupt essential physiological processes plants, leading reduced yields degraded quality. present study thoroughly investigated the potential involvement hydrogen sulphide (H 2 S) nitric oxide (NO) facilitating tolerance cucumbers. In this investigation, NaHS (sodium sulfide), which is donor H S, SNP nitroprusside), NO, were used as treatments for cucumber seedlings exposed stress. Additionally, L‐NAME (N‐nitro‐L‐arginine: 100 μM) cPTIO (2‐phenyl‐4,4,5,5‐tetramethylimidazoline‐1‐oxyl 3‐oxide), are inhibitors scavengers NO respectively, verify presence salinity. supplementation significantly boosted fresh weight, dry height, chlorophyll content, promoting under These raised endogenous S levels, upregulating antioxidative enzymes like SOD, CAT, APX, GR, GPX, GSTs. This response oxidative damages lowering reactive oxygen species (ROS) lipid peroxidation. combined application offers promising cost‐effective strategy improve resilience salinity, reduce stress, ultimately enhance crop productivity. findings provide important insights into use donors sustaining production saline environments, addressing critical global challenge food security.

Language: Английский

Citations

1
Melatonin-regulated heat shock proteins and mitochondrial ATP synthase induce drought tolerance through sustaining ROS homeostasis in H2S-dependent manner DOI Open Access
M. Nasir Khan, Manzer H. Siddiqui, Mazen A. AlSolami

et al.

Plant Physiology and Biochemistry, Journal Year: 2023, Volume and Issue: 206, P. 108231 - 108231

Published: Nov. 27, 2023

Language: Английский

Citations

19
Recent trends in hydrogen-associated treatments for maintaining the postharvest quality of fresh and fresh-cut fruits and vegetables: A review DOI
Maratab Ali,

Sara Batool,

Nauman Khalid

et al.

Food Control, Journal Year: 2023, Volume and Issue: 156, P. 110114 - 110114

Published: Sept. 21, 2023

Language: Английский

Citations

17
Hydrogen Sulfide in the Oxidative Stress Response of Plants: Crosstalk with Reactive Oxygen Species DOI Open Access
Zhiya Liu, Yayu Liu,

Weibiao Liao

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(3), P. 1935 - 1935

Published: Feb. 5, 2024

Growing evidence suggests that exposure of plants to unfavorable environments leads the accumulation hydrogen sulfide (H2S) and reactive oxygen species (ROS). H2S interacts with ROS-mediated oxidative stress response network at multiple levels. Therefore, it is essential elucidate mechanisms by which ROS interact. The molecular mechanism action relies on post-translational modification cysteine sulfur group (-SH), known as persulfidation. cannot react directly -SH, but can oxidized residues, this oxidation process induced H2O2. Evidently, involved in signaling pathway plays a significant role. In review, we summarize role H2S-mediated responses. Moreover, interaction between regulation redox reactions focused upon, positive cooperative elucidated. Subsequently, based existing clues, propose some potential problems new clues be explored, are crucial for development crosstalk plants.

Language: Английский

Citations

8